Department of Physiology & Pathophysiology
Physiology is the study of how living things, including humans, function. Through physiology, we aim to understand the fundamental mechanisms that operate in a living organism and how they interact. Physiology can be investigated at the level of the whole body, organ systems, tissues and cells at the molecular level.
Pathophysiology is the natural counterpart to physiology. It is the study of how things go wrong in living things and affect the body’s systems, causing functional changes that can lead to health consequences such as a disease or a disorder.
What we offer
Our department offers PhD and MSc graduate degrees in physiology and pathophysiology and a one-year stand-alone post-baccalaureate diploma in medical physiology and pathophysiology.
Watch a brief video to learn more about our department and what we offer.
Researchers in the Department of Physiology & Pathophysiology are carrying out leading-edge research across a broad range of disciplines.
Current faculty research
Cardiovascular Science and Disease
Cell Physiology & Pathophysiology
Endocrinology and Metabolic Diseases
Neuroscience and Spinal Cord Injury
Respiratory Physiology and Disease
Faculty and staff
Find an advisor for your graduate studies and training
You must have an advisor willing to accept you as a student to pursue graduate studies in physiology and pathophysiology. If accepted, the advisor will commit to a minimum stipend. Currently, this is $19,000 per year for two years for a MSc degree and $20,000 per year for four years for a PhD degree, but please contact us to confirm approved level and duration of support. Trainees are all encouraged, however, to apply for personnel awards that, in addition to recognition, may provide alternative or additional support during the period of training.
If you are interested in pursuing a graduate degree under the mentorship of a faculty researcher listed on this site under links to “Our researchers”, “Faculty” or “Other faculty”, you are welcome to contact that faculty member directly to inquire about potential graduate positions.
Below, however, are links to faculty members associated with our Department that are interested in receiving trainee applications at this time. Please note, while every effort is made to update this information regularly, circumstances may have changed since the last update.
When you decide to contact a faculty member regarding a graduate position, please send them the following:
- Curriculum vitae or resume
- All academic transcripts from previous post-secondary institutions as well as the University of Manitoba (as applicable)
- Descriptions of any previous research or teaching-related experience
Please also expect an invitation for interview, if your inquiry is pursued by a prospective advisor.
Advisors accepting graduate students
|Faculty advisor||Research area|
|Jeremy Chopek||Spinal cord physiology, movement, neural circuit formation (MSc and/or PhD applications accepted)|
|Shyamala Dakshinamurti||Smooth muscle cell biology, cell signaling and pharmacology, pulmonary circulation hemodynamics (MSc and/or PhD applications accepted)|
|Sanjiv Dhingra||Cardiac stem cell therapy and tissue engineering, Immunomodulatory biomaterials synthesis, characterization and application, allograft vasculopathy, iPSCs and disease modeling, Inborn metabolic disorders (MSc and/or PhD applications accepted)|
|Ian Dixon||Cardiac fibrosis, myofibroblast inactivation by endogenous repressor of Smads, generation of living valve leaflets using matricryptic signals (MSc and/or PhD applications accepted)|
|Christine Doucette||Studies on (1) the role of the circadian clock in the regulation of the pancreatic beta cell and insulin secretion, and (2) the mechanisms that contribute to beta cell dysfunction in offspring exposed to diabetes during gestation (MSc and/or PhD applications accepted)|
|Andrew Halayko||Pathobiology and pathogenesis of asthma, including the effects of inhaled pollutants, and pre-clinical testing of new therapies (MSc and/or PhD applications accepted)|
|Davinder Jassal||Complementary use of multimodality cardiovascular imaging (echocardiography, cardiac computed tomography and cardiac MRI, in the non-invasive assessment of heart failure syndromes, in the fields of cardio-oncology, women’s heart health, and sudden cardiac death (MSc applications accepted)|
|Soheila Karimi||Translational neuroscience, neural regeneration, neural stem cell biology and therapeutics, multiple sclerosis and spinal cord injury, treatment development, neuroinflammation and immune modulation, myelin repair, organoid, transgenic and genetic models (MSc and/or PhD applications accepted)|
|Richard Keijzer||Interested clinically in minimal invasive pediatric general surgery, Research is focused on congenital anomalies including congenital diaphragmatic hernia (CDH) and abnormal lung development, including delineating the role of microRNAs and circular RNAs (MSc and/or PhD applications accepted)|
|Lorrie Kirshenbaum||Cell death, autophagy, mitochondrial metabolism, hypoxia, (MSc and/or PhD applications accepted)|
|Sabine Mai||Cancer, genomic instability, nuclear architecture, imaging (MSc applications accepted)|
|Asher Mendelson||Basic science (animals, in vitro) and translational (humans) studies, microvascular physiology, critical care, sepsis, skeletal muscle dysfunction (MSc and/or PhD applications accepted)|
|Inna Rabinovich-Nikitin||Circadian factors and pathways by which circadian misalignment leads to cardiometabolic dysfunction; how controlling feeding/fasting cycles affect cardiac function in cardiometabolic syndrome and contribute or prevent the development of cardiometabolic heart failure (MSc and/or PhD applications accepted)|
|Amir Ravandi||Cardiovascular lipidomics (MSc and/or PhD applications accepted)|
|Ashish H. Shah||Hemodynamics and biomarker identification in cardiovascular diseases (MSc and/or PhD applications accepted)|
|Tabrez Siddiqui||Synapse development, synaptic plasticity, neurodevelopment, autism, schizophrenia (MSc applications accepted)|
|Peter Thompson||Type 1 Diabetes, autoimmunity, pancreatic islet biology, cellular senescence, DNA damage response, ER stress (MSc and/or PhD applications accepted)|
|Jiuyong Xie||Pre-mRNA RNA splicing, adaptation, genetic diseases, cancer, Rett syndrome, (PhD applications accepted)|
Advisors accepting postdoctoral fellows
|Faculty advisor||Research area|
Studies to examine the influence of gene/environment interactions on pancreatic islet function and metabolic health: Implications for childhood-onset type 2 diabetes in Indigenous youth
Pathobiology and pathogenesis of asthma, including the effects of inhaled pollutants, and pre-clinical testing of new therapies.
Interested clinically in minimal invasive pediatric general surgery. Research is focused on congenital anomalies including congenital diaphragmatic hernia (CDH) and abnormal lung development, including delineating the role of microRNAs and circular RNAs
Mitochondrial dynamics, cell death, autophagy, myocardial infarction
Cancer, genomic instability, nuclear architecture, imaging
Synapse development, synaptic plasticity, neurodevelopment, autism, schizophrenia (candidates with experience in electrophysiology and/or calcium imaging preferred)
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