Department of Physiology & Pathophysiology

Jeremy Chopek

Spinal cord physiology; movement; neural circuit formation (MSc and/or PhD applications accepted)

Shyamala Dakshinamurti

Smooth muscle cell biology, cell signaling and pharmacology; pulmonary circulation hemodynamics (MSc and/or PhD applications accepted)

Perry Dhaliwal

Clinical research focused on the measurement of intraspinal pressure and spinal cord perfusion following acute traumatic spinal cord injury in humans. These measures will also be studied in the context of biomarkers for spinal cord injury.

Sanjiv Dhingra

Cardiac stem cell therapy and tissue engineering, Immunomodulatory biomaterials synthesis, characterization and application, allograft vasculopathy, iPSCs and disease modeling, Inborn metabolic disorders (MSc and/or PhD applications accepted)

Ian Dixon

Cardiac fibrosis. Myofibroblast inactivation by endogenous repressor of Smads. Generation of living valve leaflets using matricryptic signals (MSc and/or PhD applications accepted)

Christine Doucette

Studies on (1) the role of the circadian clock in the regulation of the pancreatic beta cell and insulin secretion; and (2) the mechanisms that contribute to beta cell dysfunction in offspring exposed to diabetes during gestation (MSc and/or PhD applications accepted)

Andrew Halayko

Pathobiology and pathogenesis of asthma, including the effects of inhaled pollutants, and pre-clinical testing of new therapies (MSc and/or PhD applications accepted)

Davinder Jassal

Complementary use of multimodality cardiovascular imaging (echocardiography, cardiac computed tomography and cardiac MRI, in the non-invasive assessment of heart failure syndromes, in the fields of Cardio-Oncology, Women’s Heart Health, and Sudden Cardiac Death (MSc applications accepted)

Soheila Karimi

Translational neuroscience; neural regeneration; neural stem cell biology and therapeutics; multiple sclerosis and spinal cord injury; treatment development; neuroinflammation and immune modulation; myelin repair; organoid; transgenic and genetic models (MSc and/or PhD applications accepted)

Richard Keijzer

Interested clinically in minimal invasive pediatric general surgery. Research is focused on congenital anomalies including congenital diaphragmatic hernia (CDH) and abnormal lung development, including delineating the role of microRNAs and circular RNAs (MSc and/or PhD applications accepted)

Lorrie Kirshenbaum

Cell death; autophagy; mitochondrial metabolism; hypoxia. (MSc and/or PhD applications accepted)

Sabine Mai

Cancer; genomic instability; nuclear architecture; imaging (MSc applications accepted)

Asher Mendelson

Basic science (animals, in vitro) and translational (humans) studies; microvascular physiology; critical care; sepsis; skeletal muscle dysfunction (MSc and/or PhD applications accepted)

Inna Rabinovich-Nikitin

Circadian factors and pathways by which circadian misalignment leads to cardiometabolic dysfunction;

how controlling feeding/fasting cycles affect cardiac function in cardiometabolic syndrome and contribute or prevent the development of cardiometabolic heart failure (MSc and/or PhD applications accepted)

Amir Ravandi

Cardiovascular lipidomics (MSc and/or PhD applications accepted)

Ashish H. Shah

Hemodynamics and biomarker identification in cardiovascular diseases (MSc and/or PhD applications accepted)

Tabrez Siddiqui

Synapse development; synaptic plasticity; neurodevelopment; autism; schizophrenia (MSc applications accepted)

Peter Thompson

Type 1 Diabetes; autoimmunity; pancreatic islet biology; cellular senescence; DNA damage response; ER stress (MSc and/or PhD applications accepted)

Jiuyong Xie

Pre-mRNA RNA splicing, adaptation, genetic diseases, cancer, Rett syndrome, (PhD applications accepted)

Christine Doucette

Studies to examine the influence of gene/environment interactions on pancreatic islet function and metabolic health: Implications for childhood-onset type 2 diabetes in Indigenous youth

Andrew Halayko

Pathobiology and pathogenesis of asthma, including the effects of inhaled pollutants, and pre-clinical testing of new therapies.

Richard Keijzer

Interested clinically in minimal invasive pediatric general surgery. Research is focused on congenital anomalies including congenital diaphragmatic hernia (CDH) and abnormal lung development, including delineating the role of microRNAs and circular RNAs

Lorrie Kirshenbaum

Mitochondrial dynamics; cell death; autophagy; myocardial infarction

Sabine Mai

Cancer; genomic instability; nuclear architecture; imaging

Tabrez Siddiqui

Synapse development; synaptic plasticity; neurodevelopment; autism; schizophrenia (Candidates with experience in electrophysiology and/or calcium imaging preferred)

Peter Zahradka

To study non-alcoholic fatty liver disease (NAFLD) in an obese rodent model. In addition to examining the physiological processes leading to disease onset, a major objective is to identify key cellular mechanisms that may serve as targets for interventions capable of slowing or reversing disease progression.