• Suresh Mishra headshot
  • Professor

    Max Rady College of Medicine
    Internal Medicine
    Room 839 – John Buhler Research Centre
    715 McDermot Avenue
    University of Manitoba
    Winnipeg, Manitoba R3E 3P4

    Phone: 204-977-5629


Physiology and Pathophysiology, Max Rady College of Medicine

Research achievements

Research summary

Dr. Mishra’s laboratory studies the basic mechanisms involved in the interplay between adipose and immune functions in normal physiology, during aging, and in many diseases. His current research works are directed towards understanding the extent and specificity with which sex hormones, X-linked and autosomal genes/micro-RNAs expression define sex differences in adipose and immune functions, and towards elucidating potential connections between them. Identifying molecular signature of sex differences in adipose and functions expected to improve basic understanding of sex-biased metabolic and immune diseases. Ultimately, it is hoped that such studies will provide insights into why men and women are differently vulnerable to metabolic and immune diseases, and will enable the development of effective sex-tailored therapeutic modalities.

Research interests

  • Cell signaling
  • Obesity-linked diabetes and cancer
  • X-linked genes and micro-RNAs
  • Mitochondria in metabolic regulation and steroidogenesis
  • Sex differences in immunometabolism


  • Insulin resistance
  • Obesity
  • Diabetes
  • Cancer
  • Posttranslational modifications
  • Steroidogenesis
  • Mitochondria

Research groups

  • Diabetes Research Group (DRG), section of endocrinology and metabolism
  • Endocrine and Metabolic Diseases (EMD), department of physiology and pathophysiology


Dr. Mishra is a professor of endocrinology and metabolism in the department of internal medicine. He received his doctorate from the University of Delhi and post-doctoral training at the HSC University of Louisville and University of Manitoba. His laboratory has used an innovative approach to developed preclinical mouse models that spontaneously developed obesity-linked diabetes and tumors independent of diet and carcinogens, which led to successful patent applications to the United States Patent and Trademark Office (USPTO). These findings have provided new insights on the sex differences in obesity-linked metabolic dysregulation and in the development of diabetes and cancer. Recently, he has reported that an evolutionarily conserved pleiotropic protein, prohibitin, plays a role in sex differences in adipose and immune functions.

Recently, he edited a book on Immunometabolism: Methods and Protocols, which is published by Springer Nature as a part of a well-known series on Methods in Molecular Biology. Research in his laboratory is supported by Canada Foundation for Innovation (CFI), Canadian Institutes of Health Research (CIHR), and Natural Sciences and Engineering Research Council of Canada (NSERC).


  • PhD, Endocrinology, University of Delhi
  • Master of Science, University of Delhi


  • Canada Foundation for Innovation (CFI) Leaders Opportunity Award
  • Dr. Moorhouse Fellowship in Diabetes Research
  • MMSF Basic Science Career Development Award

Contact us

Internal Medicine
Room GC430, Health Sciences Centre
820 Sherbrook Street
University of Manitoba
Winnipeg, MB R3A 1R9 Canada