Max Rady College of Medicine
Physiology and Pathophysiology
Room 405 – Basic Medical Services Building
745 Bannatyne Avenue
University of Manitoba
Winnipeg, Manitoba R3E 0J9
Dr. Kristine Cowley’s research focus is to increase the health and function of people living with spinal cord injury.
Spinal cord injury is a life-altering event that causes paralysis and loss of sensation and affects virtually every bodily function because of the loss of ascending and descending neural control.
It is due to the loss of these functions that lead to the all-too-common secondary consequences of obesity, diabetes, osteoporosis, lower limb fracture and cardiovascular disease.
Her lab uses a variety of techniques and research models to identify strategies to reduce these secondary consequences and to improve function and life quality after injury. The lab uses pre-clinical and clinical research models and techniques.
Pre-clinical research techniques include electrophysiology, immunohistochemistry and fluorescence microscopy, western blot protein analysis and micro-computed tomography.
Human research techniques include kinematics, electromyography and electrical stimulation techniques, biomechanics, exercise physiological techniques and ergonomics.
Dr. Kristine Cowley is an associate professor in the physiology and pathophysiology department in the Rady Faculty of Health Sciences Max Rady College of Medicine.
She holds a Tier 2 Canada Research Chair in Health and Function after Spinal Cord Injury.
Dr. Cowley received her PhD from UM, investigating the neural control of movement.
By investigating the neural mechanisms within the spinal cord that contribute to movement and posture, she hopes to improve functional performance after neurological injury.
Her research program also seeks to identify strategies to reduce the musculoskeletal decline and costly secondary pathologies that are common after spinal cord injury, such as osteoporosis, type 2 diabetes, and cardiovascular disease.
Investigations are carried out in animal research models as well as in the population of those living with spinal cord injury. Support from the Canada Research Chairs program, Natural Sciences and Engineering Research Council of Canada (NSERC), Research Manitoba and the Manitoba Spinal Cord Research Committee enables this research.