Max Rady College of Medicine
Physiology and pathophysiology
602 – John Buhler Research Centre
715 McDermot Avenue
University of Manitoba
Winnipeg, MB, R3E 0W2
Does not hold any cross appointments.
Chronic respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD), are significant health burdens in Canadians. Research shows that both genetic and environmental risk factors are important in the development of these conditions. Although treatments exist to manage the symptoms, individuals with chronic respiratory disease still suffer significant morbidity and mortality. Through an understanding of how the early life environment influences risk for chronic disease, it may be possible to develop strategies and treatments that reduce risk and prevent disease development.
Dr. Pascoe’s team uses animal and cell models, and human clinical samples to address two research focuses:
Research groups include:
Dr. Pascoe completed a bachelor of science in biology at the University of the Fraser Valley. He went on to earn his PhD in experimental medicine at the University of British Columbia, where his research focused on airway smooth muscle contractility in the context of asthma.
He conducted his postdoctoral training at the Children’s Hospital Research Institute of Manitoba at the University of Manitoba, where he began to focus more on cell and animal models of chronic respiratory disease. It was during his post-doctoral training that he developed his interest in the developmental origins of lung disease, securing funding from the DEVOTION Network to explore the relationship between maternal diabetes and offspring lung dysfunction.
In 2017, he received the prestigious Banting Postdoctoral Fellowship for his work on the developmental origins of lung disease using an animal model.
In late 2019, he joined the Rady Faculty of Health Sciences in the department of physiology and pathophysiology as an assistant professor and principal investigator in the Children’s Hospital Research Institute of Manitoba.