Michael Czubryt, PhD, BSc(Hons)

  • Michael Czubryt headshot

  • Professor

    Max Rady College of Medicine
    Physiology and Pathophysiology
    University of Manitoba
    Room R4008 – 351 Tache Avenue
    Winnipeg, Manitoba R2H 2A6

    Phone: 204-235-3719
    Fax: 204-233-6723
    michael.czubryt@umanitoba.ca

Keywords

  • Gene regulation
  • Heart failure
  • Fibrosis
  • Transcription
  • Cell metabolism
  • Wound healing

Research affiliations

Research groups

  • Canadian Epigenetics, Environment and Health Research Consortium (CEEHRC) Network

Research summary

Dr. Czubryt’s research program focuses on the mechanisms of gene activation and repression in the heart, and how these regulatory processes contribute to or are altered in cardiovascular pathophysiology.  His laboratory has made significant advances in understanding the transcriptional regulation of cardiac fibrosis, which not only adversely affects cardiac function and arrhythmogenesis, but is now recognized as a significant independent risk factor for heart failure and death due to cardiovascular causes. Recent efforts have focused on translating these discoveries to preclinical studies and the development of novel fibrosis inhibitors for the heart and other organs.

Biography

Dr. Michael Czubryt is a principal investigator in the Institute of Cardiovascular Sciences and executive director of research at St. Boniface Hospital.

He is a full professor in the physiology and pathophysiology department at UM.
Dr. Czubryt’s work has been supported by the Heart and Stroke Foundation of Canada, the Canadian Institutes of Health Research, and the Canadian Foundation for Innovation.

Dr. Czubryt has an extensive record of service at the local, national and international level, including more than thirteen years on animal ethics committees, and is currently on the board of directors of the Canadian Council on Animal Care.

He has been a reviewer, scientific officer and chair of numerous peer review committees locally, nationally and internationally, and has served in leadership roles for professional organizations such as the American Physiological Society and the International Academy of Cardiovascular Sciences.

Dr. Czubryt also maintains an active training program that encompasses high school, undergraduate and graduate students, with more than 50 trainees mentored to date and service on the advisory committees of more than 40 graduate students.

He has published nearly 80 research articles and chapters, as well as ten editorials, and holds three patents for his research.

Education

  • CIHR/HSFC postdoctoral fellowship, University of Texas Southwestern Medical Center at Dallas (2000-2003)
  • PhD, University of Manitoba (2000)
  • Bachelor of science (honours), University of Manitoba (1990)

Awards

  • Merit Award for Research, Scholarly Activities and Service, University of Manitoba (2023)
  • The Everett Chair in Fibrosis Research (2023)
  • Distinguished Leadership Award, International Academy of Cardiovascular Sciences (2022)
  • Andras Varro Award for Excellence in Cardiovascular Sciences (2019)
  • Merit Award for Service, University of Manitoba (2019)
  • Fellow, International Academy of Cardiovascular Sciences (2016)
  • Fellow, American Heart Association (2016)
  • Ronald Duhamel Innovation Fund Award (2016)
  • Fellow, American Physiological Society Cardiovascular Section (2013)
  • Young Investigator Award, Canadian Cardiovascular Society (2006)
  • Heart and Stroke Foundation of Canada McDonald Scholarship (2004)

Contact us

Physiology and Pathophysiology
432 Basic Medical Sciences Building
745 Bannatyne Avenue
University of Manitoba
Winnipeg, MB R3E 0J9 Canada

physiology@umanitoba.ca
204-789-3696
204-789-3934