Close-up of a fluorescence microscope with green excitation light.

Services we offer

A cell with 3-color fluorescence shown as a standard wide field image and a deconvolved image.

Deconvolution

Unlock sharper, more accurate fluorescence images with our deconvolution service. By removing out-of-focus light from above and below the focal plane, we use advanced algorithms to enhance the clarity of your images. This process not only sharpens your visuals but also ensures that your data is a true representation of your sample, enabling precise, reliable analysis.

Fluorescence microscopy image showing cells with red, green, and blue fluorescence, highlighting distinct structures or regions within the cells

Fluorescence microscopy

Experience the power of fluorescence microscopy to visualize cellular structures with unparalleled detail. By tagging specific components with fluorescent markers, our system allows you to explore biological processes in vibrant, high-contrast images with resolutions down to 250 nm. With capabilities like transmitted light, z-stacks, tiling, and time-lapse imaging, we provide a comprehensive view of your dynamic research.

Tissue images with three different methods; brightfield H&E, bright field immunostained and fluorescence

GenASIs scanning system

Accelerate your research with the GenASIs scanning system. Designed for high-precision fluorescence and bright-field analysis, this automated system excels in rare cell detection and high-throughput applications. With the ability to scan up to 8 slides simultaneously, it seamlessly integrates into your workflow, offering the efficiency you need to keep your projects moving forward.

A karyotype displaying chromosomes sorted into pairs, highlighting variations and structural damage.

HyperSpectral karyotyping

Gain deeper insights into genetic variations and chromosomal aberrations with our HiSky spectral karyotyping system. This advanced technique allows for spectral analysis that delivers clear, interpretable visuals, making it easier to study genetic disorders and chromosomal abnormalities in human and mouse samples, ultimately advancing your genetic research.

3D rendering of several cells in three dimensions, with the nuclei highlighted.

Image analysis

Transform your image data into actionable insights with our cutting-edge image analysis services. Whether you're working with confocal, super-resolution, SEM, or TEM imaging systems, we offer powerful tools that incorporate AI and machine learning for efficient and precise analysis. Complex datasets are no challenge—our software ensures accuracy across all imaging platforms.

Laser microdissection image showing a small piece of tissue being precisely cut from a larger section and collected for subsequent analysis.

Laser microdissection

Isolate cells or tissue sections with pinpoint precision using our laser microdissection service. This technique is perfect for extracting RNA, DNA, proteins, or single circulating tumor cells for molecular analysis. It’s an efficient, clean method for targeting and collecting small areas from your samples, ensuring high-quality downstream analysis.

A microscopic image of a live cell using DIC contrast.

Live cell imaging

Study live cells over extended periods with our state-of-the-art live cell imaging system. Perfect for long-term experiments, it features automated multichannel, time-lapse, and positional imaging, while controlling temperature, humidity, and CO2 levels to maintain optimal cell conditions. Observe dynamic biological processes in real-time without compromising cell viability.

Two chromosomes displayed with multicolor banding patterns, showing distinct segments for analysis.

Multicolour banding (mBANDing)

Dive deep into genetic research with our multicolour banding (mBANDing) technology. By using multiple fluorescent bands, this method enhances karyotyping, allowing you to detect and classify chromosomal structures with high resolution. It’s an invaluable tool for studying genetic rearrangements and abnormalities in both human and animal samples.

Illustration of multidimensional imaging techniques, including Z-stacks for 3D visualization, multicolor imaging for multiple markers, tiling for large area coverage, and timelapse imaging for capturing dynamic changes over time.

Multi-dimensional imaging

Capture the full complexity of biological systems with our multi-dimensional imaging platform. We offer a range of imaging modes, from 2D to z-stacks, multi-colour, tiling, and time-lapse imaging, giving you the flexibility to design experiments that provide a comprehensive, multi-faceted view of your samples—ideal for exploring dynamic biological processes in detail.

Comparison image showing a triple-stained cell as viewed under wide-field microscopy and super-resolution microscopy, highlighting the enhanced detail and clarity provided by super-resolution techniques.

Super resolution

Take your research to the next level with super-resolution imaging. Our cutting-edge system pushes the boundaries of optical microscopy, allowing you to resolve molecular-level details that were previously beyond reach. Equipped with advanced lasers, optics, and analysis tools, this technology is essential for uncovering the fine details of cellular and molecular structures in your samples.

Equipment

Our facility is equipped with cutting-edge tools to support a wide range of imaging and microscopy applications.

Available equipment

The following equipment is available to assist with your research needs, providing advanced capabilities for image acquisition, analysis, and more.

We have the following items available in our facility:

  • ASI GenASIs scanning system
  • ASI HyperSpectral Imaging (HiSKY)
  • AxioVert 200 live cell system
  • Deconvolution system #1
  • Deconvolution system #2
  • Deconvolution system #3
  • Dual Head teaching microscope
  • ELYRA super resolution
  • Image Analysis
  • Image Analysis with artificial intelligence
  • MetaSystems scanning with Metafer and ISIS software
  • MMI Cellcut Plus Laser Micro Dissection
  • Pathology Imaging

Card access

The equipment is protected by card access. Users must first complete training, after which you may request card access. Those without card access will be limited to usage during business hours (9 a.m. - 5 p.m., Monday to Friday).

Training for users 

We provide individual one-on-one training that is specifically designed to the needs of your project on our microscopes. By taking our training courses, you will not only gain a better understanding of microscopy and imaging in general but also perform image acquisition and data analysis on your own shortly after the training.

Prices

Guidelines

Acknowledgment

If research supported by the University of Manitoba Nano Cell Imaging Facility and Genomic Centre for Cancer Research and Diagnosis results in a publication, we kindly request the following acknowledgment be included:

"We thank the NCIF/GCCRD at the University of Manitoba in Winnipeg, MB, for providing __________ service. ORCID 0000-0002-5797-2201."

This acknowledgment helps ensure proper recognition of the resources and expertise provided by the facility, supporting continued access and funding for our services.

Contact us

Geonomic Centre for Cancer Research and Diagnosis
745 Bannatyne Avenue
University of Manitoba
Winnipeg, MB R3E 0J9 Canada