Research theme(s)

Population therapeutics and health outcomes research


  • Attention-deficit/hyperactivity disorder (ADHD)
  • Autism Spectrum Disorder (ASD)
  • Antipsychotics
  • Direct acting antivirals
  • Hepatitis C
  • Pharmacoepidemiology
  • Psychotropic medications
  • Smoking cessation

Research summary

Pharmacoepidemiological studies of medications used in the treatment of various conditions (schizophrenia, depression, anxiety, attention deficit hyperactivity disorder, autism, and hepatitis C). Additional research projects explore the use of smoking cessation agents, patients’ perspective regarding effectiveness of medications, vaccines and health services, and the risks of neurological disorders in newborns/young children prenatally/perinatally exposed to antibiotics.

More recent projects explore the delivery of health care services to refugees in Canada, and the effects of antipsychotic therapy in patients interacting with the justice system.  Collaborations with the pan-Canadian network CNODES include population-based studies on the effects of antipsychotic and antidiabetic agents.


Silvia Alessi-Severini is a professor at the College of Pharmacy, Rady Faculty of Health Sciences and adjunct scientist, Manitoba Centre for Health Policy.

Dr. Alessi-Severini has worked extensively for provincial governments providing advice on reimbursement of new prescription medications approved for the Canadian market.

She has also served on numerous provincial and national advisory committees (e.g., Manitoba Drug Standards and Therapeutics Committee, Canadian Drug Expert Committee) and is a member of the Manitoba team of the Canadian Network for Observational Drug Effect Studies (CNODES).

Dr. Alessi-Severini has received internal and external funding from various agencies including CIHR.


PhD from the Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, 1993

Post-doctoral fellowships from the Alberta Cancer Board, Department of Pharmacology, University of Alberta


Leslie Buggey Professorship recipient

Ed Kroeger Mentorship Award recipient

Contact us

College of Pharmacy
Apotex Centre
750 McDermot Avenue West
University of Manitoba (Bannatyne campus)
Winnipeg, MB R3E 0T5 Canada