Associate professor
College of Pharmacy
Apotex Centre, 750 McDermot Ave. W.
University of Manitoba
Winnipeg, MB R3E 0T5
Phone: 204-789-3662
Fax: 204-789-3744
lucy.marzban@umanitoba.ca
Lucy Marzban, DMLS, PhD
College of Pharmacy research themes
- Translational pharmacotherapy and practice
Research affiliations
Principal Investigator, Rady Faculty of Health Sciences
Keywords
- Beta‐cell death
- Cell signaling
- Diabetes pathogenesis
- Islet amyloid
- Islet biology
- Islet inflammation
- Islet transplantation
- Molecular pharmacology
Research summary
Diabetes results from dysfunction and loss of insulin producing β-cells which reside in islets of Langerhans (small endocrine clusters) in pancreas. Islet transplantation has provided a promising approach for β-cell replacement in diabetes but is currently limited by short supply and post-transplant loss of islets. Dr. Marzban’s research program focuses on understanding how β-cells normally function and why they die in diabetes or following transplantation. Specifically, her group aims to identify the mechanisms by which protein aggregates called islet amyloid destroy β-cells. The ultimate goal of Dr. Marzban’s research is to develop new therapies to prevent or slow the onset of diabetes and enhance long-term survival of islet grafts.
Biography
Dr. Marzban is currently an associate professor at the College of Pharmacy. Prior to joining UM, she was an assistant and associate professor, University of British Columbia (UBC).
Education
Doctor of Medical Laboratory Science, Faculty of Medicine, University of Toronto Mississauga
Doctor of Philosophy, Faculty of Pharmaceutical Sciences, University of British Columbia
Postdoctoral Fellowship, Faculty of Medicine, University of British Columbia
Postdoctoral Fellowship, Medical Genetics, University of Geneva
Awards
Killam Prize, Faculty of Medicine, University of British Columbia (2016)
Student Teaching Award, Year 1 of Dental program, UBC Faculty of Dentistry (2011, 2014)
Student Teaching Award, Year 4 of Pharmacy program, UBC Faculty of Pharmaceutical Sciences (2009)
New Investigator Award, Diabetes Canada (formerly Canadian Diabetes Association)
Fellowship, Juvenile Diabetes Research Foundation International
Fellowship, Diabetes Canada (formerly Canadian Diabetes Association)
Transplant Fellowship, Canadian Institutes of Health Research/Michael Smith Foundation for Health Research
Fellowship, European Foundation for the Study of Diabetes
Bertram Hoffmeister Fellowship
Outstanding Achievement By A Postdoctoral Fellow Award, BC Children’s Hospital Research Institute
Graduate Studentship, Canadian Institutes of Health Research
Contact us
College of Pharmacy
Apotex Centre
750 McDermot Avenue West
University of Manitoba (Bannatyne campus)
Winnipeg, MB R3E 0T5 Canada
204-474-9306
204-789-3744