Associate professor
College of Pharmacy
Apotex Centre, 750 McDermot Ave. W.
University of Manitoba
Winnipeg, MB R3E 0T5
Phone: 204-789-3662
Fax: 204-789-3744
lucy.marzban@umanitoba.ca
Lucy Marzban, DMLS, PhD
College of Pharmacy research themes
- Biotargets and mechanisms of disease
- Translational pharmacotherapy and practice
Research affiliations
Principal Investigator, Rady Faculty of Health Sciences
Keywords
- Beta‐cell death
- Cell signaling
- Diabetes pathogenesis
- Islet amyloid
- Islet biology
- Islet inflammation
- Islet transplantation
- Molecular pharmacology
Research summary
Diabetes results from dysfunction and loss of insulin producing β-cells which reside in islets of Langerhans (small endocrine clusters) in pancreas. Islet transplantation has provided a promising approach for β-cell replacement in diabetes but is currently limited by short supply and post-transplant loss of islets. Dr. Marzban’s research program focuses on understanding how β-cells normally function and why they die in diabetes or following transplantation. Specifically, her group aims to identify the mechanisms by which protein aggregates called islet amyloid destroy β-cells. The ultimate goal of Dr. Marzban’s research is to develop new therapies to prevent or slow the onset of diabetes and enhance long-term survival of islet grafts.
Biography
Dr. Marzban is currently an associate professor at the College of Pharmacy. Prior to joining UM, she was an assistant and associate professor, University of British Columbia (UBC).
Education
- DMLS, faculty of medicine (UTMS)
- PhD, faculty of pharmaceutical sciences (UBC)
- Postdoctoral fellowships from the faculty of medicine (UBC) and medical genetics (University of Geneva)
Awards
- Killam Prize, faculty of medicine, UBC (2016)
- Dental program (year 1) Student Teaching Award, UBC faculty of dentistry (2011 and 2014)
- Pharmacy program (year 4) Student Teaching Award, UBC faculty of pharmaceutical sciences (2009)
- Diabetes Canada (formerly Canadian Diabetes Association) New Investigator Award
- Juvenile Diabetes Research Foundation International (JDRF) fellowship
- Diabetes Canada (formerly Canadian Diabetes Association) fellowship
- Canadian Institutes of Health Research/Michael Smith Foundation for Health Research transplant fellowship
- European Foundation for the Study of Diabetes fellowship
- Bertram Hoffmeister fellowship
- Outstanding Achievement By A Postdoctoral Fellow Award, BC Children’s Hospital Research Institute
- Canadian Institutes of Health Research graduate studentship
ORCID profile
Visit Lucy Marzban's ORCID profile for a complete listing.
Contact us
College of Pharmacy
Apotex Centre
750 McDermot Ave W
University of Manitoba (Bannatyne campus)
Winnipeg, MB R3E 0T5 Canada
204-474-9306
204-789-3744