College of Pharmacy
Apotex Centre, 750 McDermot Ave. W.
University of Manitoba
Winnipeg, MB R3E 0T5
Principal Investigator, Rady Faculty of Health Sciences
Diabetes results from dysfunction and loss of insulin producing β-cells which reside in islets of Langerhans (small endocrine clusters) in pancreas. Islet transplantation has provided a promising approach for β-cell replacement in diabetes but is currently limited by short supply and post-transplant loss of islets. Dr. Marzban’s research program focuses on understanding how β-cells normally function and why they die in diabetes or following transplantation. Specifically, her group aims to identify the mechanisms by which protein aggregates called islet amyloid destroy β-cells. The ultimate goal of Dr. Marzban’s research is to develop new therapies to prevent or slow the onset of diabetes and enhance long-term survival of islet grafts.
Dr. Marzban is currently an associate professor at the College of Pharmacy. Prior to joining UM, she was an assistant and associate professor, University of British Columbia (UBC).
Visit Lucy Marzban's ORCID profile for a complete listing.