Sylvain Lother, MD, FRCPC, DTMH

Research summary

Dr. Lother's thesis work is focused on evaluating the treatment effects of antithrombotics in community acquired pneumonia. Dr. Lother has developed an expertise in clinical trials through his work in several randomized controlled trials (RCTs) through the COVID-19 pandemic and beyond. He is part of a large and diverse international team of clinical trialists, where he is now serving as co-principal investigator for a large CIHR funded international RCT (named ATTACC-CAP) which will investigate the role of therapeutic anticoagulation in patients with community acquired pneumonia.

The ATTACC-CAP platform is a foundation for three main aims of Dr. Lother's research focus in pneumonia:

1. Evaluating treatments that prevent critical illness and improve outcomes.
2. Collecting biological samples for evaluating microbiological and host factors that predict outcomes or treatment response.
3. Improving clinical trial methods by evaluating novel consent methods in trials.

Through Dr. Lother's work and achievements, he continues to contribute to a rapidly expanding understanding of COVID-19 and other pneumonia syndromes in Manitoba and internationally.

Keywords

• pneumonia
• COVID-19
• clinical trials
• consent methods

Brief bio

Dr. Lother is an assistant professor at the University of Manitoba, sections of Infectious Diseases and Critical Care. He is an early career clinician-investigator, currently completing a Masters of Science in Community Health Sciences at the University of Manitoba with a program of research that aims to improve outcomes from life threatening respiratory infections.

Education

Master of Science, Department of Community Health Sciences, University of Manitoba (Expected April 2024)

Degree in Tropical Medicine and Hygiene, University of Alabama at Birmingham and Cayetano Heredia University (2018)

Doctor of Medicine, University of Manitoba (2013)

Bachelor of Science in Medicine, University of Manitoba (2011)

Bachelor of Science Major (Microbiology), 2009

Awards

Dr. Ethan Rubenstein Clinical Scientist Award (2021)

Diane Biehl Research Award (2020)

Hector Ma Award in Research (2019)

Joe Lee Award - Department of Critical Care and Anesthesia (2019)

Juan A. Embil Award for Excellence in Infectious Disease Research (2018)

CSCI/CIHR UBC Resident Research Prize Manuscript Award Winner (2017)