• Portrait of Dr. Saeid Ghavami.
  • Associate professor

    Max Rady College of Medicine
    Human Anatomy and Cell Science 
    110A-745 Bannatyne Ave
    University of Manitoba
    Winnipeg, MB R3E 0J9

    Phone: 204-272-3061

Research summary

Dr. Saeid Ghavami's research focuses on the interplay of three key cellular responses—apoptosis, autophagy, and the unfolded protein response (UPR)—in regulating cellular phenotype. His work investigates how these cellular mechanisms contribute to lung cancer metastasis and chemotherapy response in glioblastoma and rhabdomyosarcoma. Specifically, his research aims to understand how autophagy, UPR, and apoptosis influence metastatic phenotypes in lung cancer via Bcl2 family proteins and regulate the chemo-sensitivity of glioblastoma and rhabdomyosarcoma cells.

Research interests

  • Autophagy
  • Bcl2 family proteins
  • Cell phenotype
  • Chemo-resistance
  • Glioblastoma
  • Lung cancer
  • Mevalonate cascade
  • Mitophagy
  • Rhabdomyosarcoma


Brief bio

Dr. Saeid Ghavami is an associate professor at the Max Rady College of Medicine, University of Manitoba, specializing in human anatomy and cell science. He completed his undergraduate training at Shiraz University in 1989 and his MSc and PhD in clinical biochemistry at Tarbiat Modarres University in 1996 and 2004, respectively.

His postdoctoral training focused on the application of apoptosis, autophagy, and the unfolded protein response in regulating cell fate. Dr. Ghavami's research program targets these pathways to understand and regulate cellular phenotype.

He has received numerous prestigious awards, including the CIHR/GSK/CLA Postdoctoral Award (ranked first in Canada, 2007) and the Parker B. Francis Career Development Award (top ten in North America, 2009). Dr. Ghavami is an honorary professor and co-founder of the Autophagy Research Centre at Shiraz University of Medical Science and Tehran University of Medical Sciences, and an honorary professor at Katowice School of Technology in Poland. He serves as an associate editor for several journals, including BBA-Molecular Basis of Disease, Molecular Neurobiology, BB Reports, and IJMS.


  • Honorary professor and co-founder, Autophagy Research Centre, Shiraz University of Medical Science
  • Honorary professor and co-founder, Autophagy Research Centre, Tehran University of Medical Sciences
  • Honorary professor, Katowice School of Technology, Poland


  • Doctor of philosophy in clinical biochemistry, Tarbiat Modarres University, Tehran, Iran (2004)
  • Master of science in clinical biochemistry, Tarbiat Modarres University, Tehran, Iran (1996)
  • Bachelor of science in chemistry, Shiraz University, Shiraz, Iran (1989)



  • Top 0.1% article in neuroscience: Ghavami et al., Progress in Neurobiology, 2014
  • Top 10% highly cited paper in PLOS ONE: Ghavami et al., PLOS ONE, 2011


  • Life Achievement Award for Impact on Science from Iranian Presidency Office (November)


  • CIHR/CCS/OICR Early Career New Investigator Award (November)
  • Science and Innovation Center Rising Star of Research from American Thoracic Society RSF Assembly (May)


  • Ranked as 5th biomedical researcher in 18th International Razi Medical Award (March)


  • Parker B. Francis Career Development Fellowship in Respiratory Disease, Role of S100A8/A9 in Airway Remodeling in Asthma ($156,000 USD), (Ranked top ten in North America)


  • Manitoba Research Day First Prize in Post-Doctoral Category ($1,500 CDN) (June)
  • CIHR/CLA/GSK Post-Doctoral Award in Respiratory Disease ($90,000 CDN) (Ranked number 1 in basic research in Canada) (2008-2010)


  • CIHR National Training Program in Allergy and Asthma Post-Doctoral Award ($12,000 CDN)
  • Manitoba Institute of Child Health Post-Doctoral Award ($70,000 CDN)


  • Manitoba Health Research Council Post-Doctoral Award ($38,750 CDN) (Ranked number 1 in Manitoba)


  • CancerCare Manitoba Foundation Post-Doctoral Award ($30,000 CDN)


  • Iran Ministry of Health and Medical Education-Postgraduate Scholarship

Contact us

Human Anatomy and Cell Science
130 Basic Medical Science Building
745 Bannatyne Avenue

University of Manitoba
Winnipeg, MB R3E 0J9 Canada