• Dr. Ryan Zarychanski
  • Professor
    Lyonel G Israels Research Chair in Hematology

    Max Rady College of Medicine
    Internal Medicine
    ON4005-675 McDermot Ave (CCMB)
    University of Manitoba
    Winnipeg, Manitoba R3E 0V9

    Phone: 204-787-8641

  • Research themes

    • Hematologic aspects of critical illness
    • Transfusion; blood conservation
    • Anticoagulation in sepsis and in COVID-19
    • Plasmapheresis
    • Adaptive platform trials
  • Research groups

    • Chair, Trials, Epidemiology in Acute Care Hematology (TEACH) Research Collaborative
    • Centre for Transfusion Research
    • Canadian Critical Care Trials Group
  • Research affiliations

    • CancerCare Manitoba Research Institute (CCMR)
    • CancerCare Manitoba
  • Research interests

    • Bayesian adaptive platform trials; sepsis; anticoagulation
  • Keywords

    • Hematology
    • Transfusion
    • Blood conservation
    • Anticoagulation
    • Sepsis
    • COVID-19
    • Plasmapheresis
    • Adaptive platform trials


Dr. Zarychanski is a professor of internal medicine at the Max Rady College of Medicine. He is a hematologist, critical care physician and clinician-scientist at the University of Manitoba and CancerCare Manitoba.

His research focuses on the hematologic aspects of critical illness where he leads several national and international randomized trials in the fields of sepsis and anticoagulation and transfusion medicine, including anticoagulation in vasodilatory shock, plasma exchange in sepsis, and tranexamic acid in major non-cardiac surgery.

He recently served as the chair for two international adaptive platform trials evaluating anticoagulation strategies in COVID-19 and contributed to the establishment of a novel method of global collaboration in clinical trials, including the multiplatform trial.

In collaboration with the Canadian Critical Care Trials Group, Dr. Zarychanski is chairing the development of a CIHR-funded national acute care platform trial.


Master of Science, University of Ottawa (2010)

Clinical Investigator Program, University of Ottawa (2008)

Critical Care Fellowship, University of Manitoba (2006)

Haematology Fellowship, University of Manitoba/CancerCare Manitoba (2005)

Internal Medicine Residency, University of Manitoba (2003)

Doctor of Medicine, University of Ottawa (2000)

Bachelor of Science in Medicine, University of Manitoba (2000)

Bachelor of Science, University of Manitoba (1995)



  • Physician of the Year, Doctors Manitoba


  • Excellence in Research and Mentorship Award, Department of Medical Oncology and Hematology, CancerCare Manitoba
  • Canadian Hematology Paper of the Year, Canadian Hematology Society


  • G. Israels Research Chair in Hematology


  • Mentor of the Year Award, Royal College of Physicians and Surgeons of Canada


  • Excellence in Research and Mentorship Award, CancerCare Manitoba
  • Doctors Manitoba Scholastic Award


  • Lyonel G. Israels Professorship in Hematology, University of Manitoba


  • CFPC Continuing Professional Development (CPD) Award, College of Family Physicians of Canada
  • Joe Doupe Memorial Lecture, University of Manitoba

Dr. Ryan Zarychanski In the news

Contact us

Internal Medicine
Room GC430, Health Sciences Centre
820 Sherbrook Street
University of Manitoba
Winnipeg, MB R3A 1R9 Canada