• Paul McLaren.
  • Adjunct professor

    Max Rady College of Medicine
    Medical Microbiology and Infectious Diseases
    Room 543 - 745 Bannatyne Avenue
    University of Manitoba
    Winnipeg, Manitoba R3E 0J9

    Phone: 204-789-6538  
    paul.mclaren@umanitoba.ca

Research achievements

Research summary

Dr. McLaren heads the host genomics program in the National Lab for HIV Genetics where his group uses bioinformatic and molecular techniques to study how the human genome can be leveraged to inform knowledge of drivers of infection susceptibility, disease progression and response to treatment.

    • Research affiliations

      Research scientist, Public Health Agency of Canada (PHAC)

      Research groups

      • National Lab for HIV Genetics
      • International Collaboration for the Genomics of HIV
    • Research interests

      • Bioinformatics
      • Gene editing
      • HIV host genetics
      • Immunity
      • Microbiome
      • Molecular biology

    Biography

    Dr. McLaren received his PhD from the University of Manitoba in 2008 for work that described an association between a reduced T cell activation state and natural resistance to HIV infection in a highly exposed human population.

    From there, Dr. McLaren pursued his post-doctoral research at the Brigham and Women's Hospital/Harvard Medical School and the Broad Institute examining how the human genome contributes to elite HIV control.

    In 2012, Dr. McLaren joined the Swiss Federal Institute of Technology in Lausanne, Switzerland as junior group leader in bioinformatics where he helped to establish the International Collaboration for the Genomics of HIV.

    A global collaborative effort that to date has combined genetic and phenotypic data on >12,000 people living with HIV to address how host and viral genomes interact to modify the natural history of infection.

    Dr. McLaren started his research group in the department of medical microbiology and infectious diseases in 2015.

      • Education 

        B.Sc. Genetics (Hons), University of Manitoba (1999)

        PhD medical microbiology and infectious diseases, University of Manitoba (2008)

      • Awards 

        Collaboration for AIDS Vaccine Discovery Young/Early Career Investigator Award (2012)

        Conference on Retroviruses and Opportunistic Infections Young Investigator Award (2011)

        Apotex Fermentation Major Thesis Award for Molecular Biology (2008)

      Contact us

      Medical Microbiology and Infectious Diseases
      Max Rady College of Medicine
      Room 543 - 745 Bannatyne Avenue
      University of Manitoba (Bannatyne campus)
      Winnipeg, MB R3E 0J9 Canada

      204-789-3299
      204-789-3926