Accepting graduate students

Research themes


Research affiliations

Research scientist, Children’s Hospital Research Institute of Manitoba (CHRIM)

Research summary

The Manitoba Neurosurgery Laboratory (MNL) focuses primarily on the neuroengineering-based study of biosignals acquired in vivo from the human brain, during extra- and intra-cranial electroencephalogram (EEG) recordings and from magnetic resonance imaging (MRI)-based signals, during the standard work-up of epilepsy patients with medically refractory seizures.
Neuroengineering techniques drawing on nonlinear dynamics, complexity, phase synchrony and fractal methods offer innovative insights into the study of human EEG recordings, including the study of background neuronal noise and high-frequency signals, and may be used to identify novel mathematical markers underscoring the transition to the epileptic state. Additional post-processing methods may be used to analyze MRI scans in the hopes of further identifying epileptogenic targets for surgical resection. The combination of these computer-based methodologies therefore enhances the identification of epileptogenic neural networks, offering new insight into the mechanisms of epileptogenesis and underscoring potential foci for therapeutic intervention.
The MNL also supports research initiatives into many other diverse aspects of neurosurgery and the neurosciences, spanning the clinical, basic science and historical realms.


Dr. Demitre Serletis is an associate professor of neurosurgery at UM and treats pediatric and adult patients at the Children’s Hospital and the Health Sciences Centre in Winnipeg. He specializes in epilepsy and pediatric neurosurgery and serves as Director of the Epilepsy Surgery Program. Dr. Serletis is also the neurosurgery residency program director and an accomplished Ph.D. scientist in the field of neuroengineering. He currently directs the Manitoba Neurosurgery Laboratory at the Children’s Hospital Research Institute of Manitoba.



  • Nominee/Finalist, Outstanding Postgraduate Surgical Educator Award, Conference for the Advancement of Surgical Education, Canadian Undergraduate Surgical Education Committee (2020)
  • CBC Manitoba Future 40 Award (2017)
  • Innovator Award, Grand Rounds Program, surgery, University of Manitoba (2017)

ORCID profile

Visit Demitre Serletis' ORCID profile for a complete listing.

Demitre Serletis' profile

Contact us

Max Rady College of Medicine
AE101-820 Sherbrook Street
University of Manitoba (Bannatyne campus)
Winnipeg, MB R3A 1R9 Canada