• Portrait of Dr. Demitre Serletis
  • Associate professor

    Max Rady College of Medicine
    GB1 - 820 Sherbrook Street
    Winnipeg Manitoba
    Canada R3A 1R9

    Phone: 204-787-7221
    Fax: 204-787-3851


  • Adjunct member, biomedical engineering, Faculty of Engineering
  • Affiliate member, physiology and pathophysiology, Max Rady College of Medicine

Research summary

Under the leadership of Dr. Demitre Serletis, the Manitoba Neurosurgery Laboratory (MNL) is pushing the boundaries of neuroengineering with their cutting-edge research on in vivo biosignals acquired from the human brain. By utilizing non-invasive techniques such as extra- and intra-cranial electroencephalogram (EEG) recordings and magnetic resonance imaging (MRI) scans, the MNL is able to gain a deeper understanding of the complex neural networks that underlie epilepsy.

The team's innovative use of neuroengineering techniques, including nonlinear dynamics, complexity, phase synchrony and fractal methods, allows them to identify novel mathematical markers that can be used to better understand the transition to the epileptic state.

The MNL also employs advanced post-processing methods to analyze MRI scans, in the hopes of identifying specific targets for surgical resection. This combination of computer-based methodologies has the potential to revolutionize our understanding of epileptogenesis, opening up new possibilities for therapeutic intervention. By delving deeper into the intricacies of the human brain, the MNL is on the forefront of uncovering new and exciting insights into the underlying causes of epilepsy.


    Research themes


    Research affiliations

    Research scientist, Children’s Hospital Research Institute of Manitoba (CHRIM)

  • Keywords

    • Brain Networks
    • Complexity
    • Electrophysiology
    • Epilepsy
    • Imaging Post-processing Techniques
    • Nonlinear Dynamics
    • Neuroengineering
    • Pediatric Neurosurgery
    • Phase Synchrony
    • Surgical Intervention


Dr. Demitre Serletis is a highly accomplished neurosurgeon and neuroscientist, currently serving as an associate professor of neurosurgery at the Max Rady College of Medicine at the University of Manitoba. He is also an adjunct member of the biomedical engineering faculty and an affiliate member of the psychiatry and pathophysiology department. Dr. Serletis specializes in the treatment of epilepsy and pediatric neurosurgery, and currently directs the Epilepsy Surgery Program at the Children's Hospital and the Health Sciences Centre in Winnipeg. He also serves as the neurosurgery residency program director and directs the Manitoba Neurosurgery Laboratory at the Children’s Hospital Research Institute of Manitoba. Dr. Serletis is a Fellow of the Royal College of Physicians of Canada and holds a PhD in physiology and biomedical engineering.

  • Education

    Fellowship in Epilepsy Surgery, Cleveland Clinic (2013)

    Fellow of the Royal College of Physicians of Canada in Neurosurgery, University of Toronto (2012)

    Doctor of Philosophy in Physiology and Biomedical Engineering, University of Toronto (2010)

    Medical Doctorate, University of Calgary (2003)

    Bachelor of Science in Biological Sciences, University of Calgary (2001)


  • Awards

    Nominee/Finalist for Outstanding Postgraduate Surgical Educator Award, Conference for the Advancement of Surgical Education, Canadian Undergraduate Surgical Education Committee (2020)

    CBC Manitoba Future 40 Award (2017)

    Innovator Award, Grand Rounds Program in Surgery, University of Manitoba (2017)

Contact us

Max Rady College of Medicine
AE101-820 Sherbrook Street
University of Manitoba (Bannatyne campus)
Winnipeg, MB R3A 1R9 Canada