Distinguished professor
Max Rady College of Medicine
Pediatrics and Child Health
Room 711C - 715 McDermot Avenue
Winnipeg, Manitoba R3E 3P4
Phone: 204-789-3779
Fax: 204-789-3907
cgreenberg@hsc.mb.ca
Cheryl Rockman-Greenberg MD, CM, FRCPC, FCCMG
Cross-appointment
Biochemistry and medical genetics, Max Rady College of Medicine
Research summary
Dr. Cheryl Rockman-Greenberg is a trailblazer in the field of medical research, leading the charge in identifying and combating the genetic disorders that are over-represented in Manitoba's unique populations. As head of the Children’s Hospital Research Institute of Manitoba (CHRIM), she and her team are revolutionizing the field of metabolic genetics by developing cutting-edge diagnostic and newborn screening programs that are saving lives and improving patient care.
Her groundbreaking research includes DNA-based newborn screening for CPT1 deficiency in the Hutterites and Inuit, and DNA-based newborn screening for glutaric academia type 1 (GA1) among the Oji Cree, which are providing early detection of metabolic genetic disorders that are amendable to effective treatment, before symptoms appear. With universal newborn screening for severe combined immunodeficiency disease added to the panel of disorders screened at birth based on her research findings and pilot programs, Dr. Rockman-Greenberg is making a real difference in the lives of families in Manitoba.
As a member of the Global HPP Consortium for Functional Testing of Genetic Variants in the ALPL gene, Dr. Rockman-Greenberg is at the forefront of uncovering the molecular basis for hypophosphatasia and identifying the mutations distinguishing the infantile from the juvenile and adult forms of the disease. Her team is also actively involved in clinical trials of enzyme replacement therapy and substrate reduction therapy for HPP and Fabry disease, which are advancing the field of metabolic genetics and providing hope for patients suffering from these debilitating disorders. These clinical trials are multicenter, multinational and may be industry-sponsored.
With a passion for knowledge translation, Dr. Rockman-Greenberg is dedicated to taking the latest research findings and making them available to patients and their families, ensuring they are always at the center of health care recommendations. She is also interested in partnering with multiple stakeholders and participating in provincial and national strategies to develop innovative and transparent programs for the approval, equal access and reimbursement of new drugs for rare and ultra-rare hereditary disorders, making her a true leader in the field of medical research.
-
Research affiliations
Research scientist, Children’s Hospital Research Institute of Manitoba (CHRIM)
Research groups
Metabolic Disorders Clinical Trials Research Team (MDCTCT) - Local
Canadian Metabolic Disorders Research Network (CIMDRN)
Member, Global HPP Consortium for Functional Testing of Genetic Variants in the ALPL gene in the causation of hypophosphatasia
-
Keywords
- Metabolic disorders
- Hereditary metabolic disorders
- Newborn screening
- Clinical trials
- Genomics
- Lysosomal storage diseases
- Hypophosphatasia
- Enzyme replacement therapy
- Substrate reduction therapy
- Genetic disorders screening
Biography
Dr. Cheryl Rockman-Greenberg is a pioneering researcher in the field of metabolic genetics, known for her work in identifying and combating the genetic disorders that are over-represented in Manitoba's unique populations. With a medical degree from McGill University, and a fellowship in medical genetics from the University of British Columbia, she has dedicated her career to improving the lives of those affected by metabolic disorders.
As a pediatric geneticist and metabolic specialist at the Children's Hospital Research Institute of Manitoba for over 30 years and a professor at the Max Rady College of Medicine, University of Manitoba, she has developed cutting-edge diagnostic and newborn screening programs that have saved countless lives and improved patient care.
Dr. Rockman-Greenberg currently serves as a metabolic geneticist at the Winnipeg Regional Health Authority, a clinician scientist in the Children’s Hospital Research Institute of Manitoba, and a distinguished professor of pediatrics and child health and biochemistry and medical genetics at the University of Manitoba.
A Fellow of the Royal College of Physicians and Surgeons of Canada and the Canadian College of Medical Geneticists, Dr. Rockman-Greenberg has received numerous awards and accolades for her work. She continues to be a leader in the field, dedicated to improving the lives of those affected by metabolic disorders.
Education
Doctorate equivalent, residency in pediatrics, biochemical and medical genetics, Montreal Children's Hospital (1987)
Master's equivalent, Medical Research Council fellowship in human genetics, University of Manitoba (1986)
Doctorate in medicine and surgery, McGill University (1974)
Bachelor of science in genetics, McGill University (1971)
Awards
Inductee, officer, Order of Canada (2020)
Ace Burpee's Top 100 Most Fascinating Manitobans (2018)
Inductee, Order of Manitoba (2018)
Inductee, Canadian Medical Hall of Fame: Leadership in Health Promotion, Illness Prevention and Care (2018)
Canadian Medical Association honorary membership (2017)
Founders Award for Excellence in Medical Genetics, Canadian College for Medical Geneticists (2017)
Best of 2016, Journal of Clinical Endocrinology and Metabolism (2016)
Health Research Foundation Medal of Honour (HRF Medal of Honour), Innovative Medicines Canada (2016)
Partners in Research' National Award: Biomedical Science Ambassador Award (2015)
Inductee, Canadian Academy of Health Sciences (2014)
Dr. John M. Bowman Memorial Winnipeg Rh Institute Foundation Award (2014)
Canadian Organization for Rare Disorders "Rarity" Award (CORD "Rarity" Award) (2013)
Canada's Most Powerful Women Top 100 - Women's Executive Network (2012)
Henning Andersen Prize for Best Clinical Abstract, European Society for Pediatric Endocrinology Meeting (2010)
Community Service Award Huntington Society of Canada Distinction (2008)
Physician of the Year - Scholastic Category, Doctors Manitoba (2008)
Research Award for Visiting Professor, German Academic Exchange Service (DAAD), Heidelberg, Germany, Distinction Metabolic Genetics (2002)
Contact us
Pediatrics and Child Health
CE-208 Children's Hospital, Health Sciences Centre
840 Sherbrook Street
University of Manitoba
Winnipeg, MB R3A 1S1 Canada
204-787-8020
204-787-4807