Jean-Eric Ghia, MSc, PhD, HDR, AGAF

Dr. Jean-Eric Ghia's research delves into the complex neuro-immune and endocrine mechanisms underlying inflammatory bowel diseases (IBD). His work aims to define the roles of chromogranin-derived peptides, the autonomic nervous system, and central disorders in gastrointestinal inflammation. By understanding these intricate mechanisms, Dr. Ghia seeks to identify new therapeutic targets and agents for treating ulcerative colitis and Crohn's disease.

Dr. Ghia's team is dedicated to advancing knowledge on the interactions between the autonomic nervous system and immune cells during IBD progression. They specifically investigate the roles of the vagus nerve and macrophages in mediating inflammatory responses within the gastrointestinal tract. Additionally, his research addresses the psychological aspects of IBD, such as anxiety and depression, and their impact on disease severity and patient quality of life.

Using a multidisciplinary approach that combines basic science, translational research, and clinical collaboration, Dr. Ghia aims to develop innovative strategies for preventing and treating IBD. His research has the potential to pave the way for novel therapeutic avenues, ultimately improving outcomes for patients suffering from these chronic inflammatory conditions.

Supported by his CFI grant, Dr. Ghia has established a local translational IBD research program by creating a neurogastroenterology lab. This lab tests novel colitis prevention strategies and provides resources, such as colonoscopy and USSING, for other laboratories.

Dr. Ghia's extensive research network and program have facilitated significant clinical collaborations. His trainees have received over $300,000 in scholarships and other awards while working in his lab.

Brief bio

Dr. Jean-Eric Ghia is a professor in the Department of Immunology at the Max Rady College of Medicine, University of Manitoba, and the director of Gastrointestinal Basic Biology Research at the Manitoba IBD Clinical Research Centre. He leads a multidisciplinary team focused on advancing the understanding and treatment of inflammatory bowel diseases (IBD).

Dr. Ghia has delivered over 52 invited lectures at universities, scientific conferences, and public forums. He has also co-organized several conferences and symposia.

He is a member of several national and international scientific panels and currently chairs the Department of Immunology's External Communication & Outreach and Undergraduate Education committees. Since 2015, Dr. Ghia has been active in scientific popularization through a bi-monthly segment on French CBC radio and a TV segment. Additionally, he contributed to the bilingual magazine "Science Mag junior," helping explain COVID-19 to children.

Cross-appointments

• Internal Medicine (Section of Gastroenterology)

Education

• Academic Health Sciences Leadership Program, George & Fay Yee Center for Healthcare Innovation (2020)
• Habilitation, Faculty of Health Sciences, University of Strasbourg, France (2012)
• Learning & Teaching Certificate, Centre for the Advancement of Teaching and Learning, University of Manitoba (2016)
• Doctor of Philosophy in Neurosciences, Faculty of Health Sciences, University of Strasbourg, France (2003)
• Master of Cellular Biology and Physiology with Honours, Faculty of Health Sciences, University of Strasbourg, France (1999)
• Bachelor of Biology and Physiology, Faculty of Health Sciences, University of Strasbourg, France (1998)