Yoav Keynan, MD, PhD

Research summary

Dr. Yoav Keynan's research focuses on the immune and genetic factors involved in immune activation and their roles in HIV acquisition, progression, and end-organ dysfunction. His multidisciplinary approach integrates epidemiology, clinical aspects, microbiome studies, and host immune responses to understand pulmonary infections in HIV-infected individuals. Additionally, Dr. Keynan investigates early markers of tuberculosis acquisition and factors that determine susceptibility. His projects utilize local and international cohorts, with growing collaborations in Medellin, Colombia.

Research interests

• HIV disease progression: immunogenetic determinants and anti-inflammatory interventions
• Influenza: innate and adaptive immune responses to infection and vaccination
• Infectious disease management: pyogenic liver abscess, HIV care, opportunistic infections
• Latent to active TB transition: host gene expression and cytokine profile

Research affiliations

• Scientific director, National Collaborating Centre for Infectious Diseases (NCCID)

Brief bio

Dr. Yoav Keynan is a professor in the departments of internal medicine, and medical microbiology and infectious diseases at the Max Rady College of Medicine, University of Manitoba. He is also an Ad Honorem professor at Universidad Pontificia Bolivariana in Medellin, Colombia. A clinician-scientist and infectious diseases consultant, Dr. Keynan serves as the scientific director of the NCCID, focusing on knowledge translation for vulnerable populations.