• Yaov Keynan headshot
  • Head, Section of Infectious Diseases
    Associate professor

    Max Rady College of Medicine
    Internal Medicine
    Room 507, Basic Medical Sciences Building
    745 Bannatyne Avenue
    University of Manitoba
    Winnipeg, Manitoba R3E 0J9

    Phone: 204-480-1317
    Phone: 204-977-5681 (assistant)
    Fax: 204-789-3926


Research summary

His research focuses on immune and genetic determinants of immune activation and the role they play in HIV acquisition, progression and end-organ dysfunction. The laboratory is using a multidisciplinary approach to the study of pulmonary infections among HIV infected individuals, combining epidemiology, clinical aspects as well as study of the microbiome and the interaction with host immune responses. Additional area of research revolves around early markers of tuberculosis acquisition and determinants of susceptibility. The projects rely on local and international cohorts with growing collaboration and exchange in Medellin, Colombia.

Research focus and interests

  • Innate and adaptive (T and B cell) immune responses to influenza infection and vaccination with emphasis on factors associated with Influenza cross-protection and disease severity
  • HIV disease progression. Study of the immunogenetic determinants and the effect of anti-inflammatory interventions on immune reconstitution
  • Tuberculosis: Host gene expression and cytokine profile used to identify latent TB infection and the transition to active disease
  • Clinical management of infectious diseases, pyogenic liver abscess caused by hypermucoviscous klebsiella; HIV care and management of opportunistic infections. POC detection of HIV status.

Research affiliations


  • Antibody response
  • CD8 response
  • Flowcytometry
  • HIV immunology
  • Influenza
  • Suspension bead array


Dr. Keynan is an associate professor, departments of internal medicine, medical microbiology and infectious diseases, and community health sciences, and Ad Honorem professor at Universidad Pontificia Bolivariana in Medellin, Colombia. He is a clinician-scientist, infectious diseases consultant in the Winnipeg Regional Health Authority and the Manitoba HIV Program. He is the scientific director of the National Collaborating Centre for Infectious Diseases (NCCID) at the University of Manitoba focusing on infectious diseases knowledge translation for vulnerable populations.


Doctorate of Philosophy (PhD) in Infectious Diseases/Medical Microbiology with a focus on Viral Immunology, completed in Dr. Keith Fowke’s Laboratory (2014)

Certified specialty in Internal Medicine (2004)

Residency completed in the Division of Medicine at Carmel Medical Center, Haifa, Israel (2004)

Completion of residency license examinations with honors (2003)

Internship at Meir Medical Center, Kfar-Saba, Israel (1995)

Doctor of Medicine from the Faculty of Health Sciences at Ben-Gurion University of the Negev, Israel (1994); Named to the Dean’s list in 1991, 1992, and 1993

Elective in Pediatric Neurology at Albert Einstein College of Medicine, Bronx, NY, with honor (1992)

Elective in Rheumatology at Albert Einstein College of Medicine, Bronx, NY (1992)

Select awards

Sorted newest first:


  • Doctors Manitoba, Scholastic Award
  • Manitoba Medical Students' Association (MMSA) teaching awards-Med II Best teaching in small group setting


  • Canadian Foundation for Infectious Diseases/ AMMI, Dr. John M. Embil Mentorship Award in Infectious Diseases


  • Faculty Educator of the Year Award, Department of Medical Microbiology and Infectious Diseases


  • Dr. Ethan Rubinstein Memorial Clinician Scientist Award, Department of Medical Microbiology and Infectious Diseases


  • Excellence in Teaching Award, Department of Internal Medicine, University of Manitoba

Contact us

Internal Medicine
Room GC430, Health Sciences Centre
820 Sherbrook Street
University of Manitoba
Winnipeg, MB R3A 1R9 Canada