• Portrait of Marc DelBigio.
  • Professor

    Max Rady College of Medicine
    Room 401 - 727 McDermot Avenue
    University of Manitoba
    Winnipeg, Manitoba R3E 3P5

    Phone: 204-789-3378  
    Fax: 204-789-3931

Research themes

  • Neuroscience / neurobiology / neuropathology
  • Hydrocephalus - pathogenesis of brain damage and shunt failure
  • Brain damage associated with prematurity and birth
  • Brain trauma / forensic neuropathology
  • Brain disease associated with metabolic and inheritable genetic disorders
  • Brain damage caused by solvent abuse
  • Fetal alcohol spectrum disorder (epigenetic and neuronal changes)

Research affiliations

Research scientist, Children’s Hospital Research Institute of Manitoba (CHRIM)

Research summary

Understanding the pathogenesis of brain disease, particularly those affecting children, by detailed studies of human autopsies and through use of animal models. Methods include: autopsy, animal models, immunohistochemistry, light and electron microscopy, biochemical assays.


Dr. Del Bigio is originally from Winnipeg, Manitoba. After completing his MD and PhD training at UM, he began training in neurosurgery. However, his true calling was found to be neuropathology. Following residency training at the University of Toronto and post-doctoral studies at the Université de Paris, he joined the faculty at UM and the staff at Health Sciences Centre - Winnipeg in 1994. He is now a professor of pathology in the Rady Faculty of Health Sciences. His clinical and research activities in neuropathology are devoted to understanding the pathogenesis of human neurological disorders. He strives to ensure that experimental and animal models are relevant to the human disease state. He has continuously had external funding awards to ensure protected research time (~60%) and operating awards from a range of Canadian and American granting agencies (MRC, CIHR, Heart & Stroke, NIH). He served as chair of the Royal College of Physicians and Surgeons of Canada (RCPSC) – Specialty Committee in Neuropathology from 2008-14. He then served as president of the Canadian Association of Neuropathologists from 2015-18. He began serving as a core council member for the International Society of Neuropathology (ISN) in 2018 and is currently senior associate editor for the ISN’s journal Brain Pathology.


  • MD University of Manitoba (1982)
  • PhD (anatomy / neurobiology) University of Manitoba (1987)
  • Residency (neurosurgery) University of Manitoba (1987-89)
  • Post-doctorate (neurobiology) University of Saskatchewan (1989)
  • Residency (neuropathology) University of Toronto (1990-1993) (FRCPC - Neuropathology)
  • Post-doctorate (neurobiology) Université de Paris (INSERM U134, Hôpital de la Salpétrière) (1993-1994)


  • Manitoba Health Research Council, Scholarship (1996-1999)
  • Rh Award for Outstanding Contributions to Scholarship and Research (1998)
  • Manitoba Medical Service Foundation Clinical Research Professorship (2001-2004)
  • Canada Research Chair in Developmental Neuropathology, Tier 1 (2004-2010, 2011-2017)
  • Robert H. Pudenz Award for Excellence in CSF Physiology Research (2009)
  • Royal College of Physicians and Surgeons of Canada – Mentor of the Year (2014)
  • Canadian Academy of Health Sciences - Fellow (2017)

ORCID profile

Visit Marc Del Bigio's ORCID profile for a complete listing, or view his PubMed page.

Marc Del Bigio's profile

Contact us

Max Rady College of Medicine
401 Brodie, 727 McDermot Avenue
University of Manitoba (Bannatyne campus)
Winnipeg, MB R3E 3P5 Canada