• Portrait of Marc DelBigio.
  • Professor

    Max Rady College of Medicine
    Pathology
    Room 401 - 727 McDermot Avenue
    University of Manitoba
    Winnipeg, Manitoba R3E 3P5

    Phone: 204-789-3378  
    Fax: 204-789-3931
    marc.delbigio@umanitoba.ca

Research summary

Dr. Marc Del Bigio's research focuses on the pathogenesis of brain disease, particularly those affecting children, with specific interests in hydrocephalus, brain damage associated with prematurity and birth, brain trauma, forensic neuropathology, brain disease associated with metabolic and inheritable genetic disorders, brain damage caused by solvent abuse, and fetal alcohol spectrum disorder. He conducts detailed studies of human autopsies and uses animal models, as well as methods such as immunohistochemistry, light and electron microscopy, and biochemical assays.

Research themes

  • Neuroscience / neurobiology / neuropathology
  • Hydrocephalus - pathogenesis of brain damage and shunt failure
  • Brain damage associated with prematurity and birth
  • Brain trauma / forensic neuropathology
  • Brain disease associated with metabolic and inheritable genetic disorders
  • Brain damage caused by solvent abuse
  • Fetal alcohol spectrum disorder (epigenetic and neuronal changes)

Research affiliations

Research scientist, Children’s Hospital Research Institute of Manitoba (CHRIM)

Keywords

Animal models

Autopsy research

Brain development

Brain trauma

Epigenetics

Fetal alcohol spectrum disorder

Hydrocephalus

Inheritable genetic disorders

Neuropathology

Pathogenesis of brain disease

Prematurity

Solvent abuse

Biography

Dr. Marc Del Bigio is a professor of pathology in the Max Rady College of Medicine. With over two decades of experience in the field of neuropathology, Dr. Del Bigio is considered a recognized leader in the study of human neurological disorders.

Dr. Del Bigio received his MD and PhD in anatomy/neurobiology from the University of Manitoba in 1982 and 1987, respectively. He continued his medical training with a residency in neurosurgery at the University of Manitoba from 1987 to 1989, followed by a post-doctoral fellowship in neurobiology at the University of Saskatchewan in 1989. Dr. Del Bigio then completed a residency in neuropathology at the University of Toronto from 1990 to 1993, earning his FRCPC in neuropathology. He continued his post-doctoral training in Neurobiology at the INSERM U134 at the Hôpital de la Salpétrière in Paris from 1993 to 1994.

Dr. Del Bigio has been recognized for his outstanding contributions to scholarship and research with numerous awards and accolades, including the Rh Award for Outstanding Contributions to Scholarship and Research, the Royal College of Physicians and Surgeons of Canada – Mentor of the Year award, and the Canadian Academy of Health Sciences Fellowship. He has also been awarded funding from a range of Canadian and American granting agencies, including the Manitoba Health Research Council, the Canadian Institutes of Health Research, and the National Institutes of Health.

Dr. Del Bigio is a research scientist at the Children's Hospital Research Institute of Manitoba (CHRIM), where he continues to conduct his research. He has also served as the chair of the Royal College of Physicians and Surgeons of Canada (RCPSC) – Specialty Committee in Neuropathology and the president of the Canadian Association of Neuropathologists. He currently serves as a core council member for the International Society of Neuropathology (ISN) and is a senior associate editor for the ISN’s journal, Brain Pathology.

Education

Doctor of Medicine (MD), University of Manitoba (1982)

Doctor of Philosophy (PhD) in anatomy/neurobiology, University of Manitoba (1987)

Residency in neurosurgery, University of Manitoba (1987-89)

Post-doctorate in neurobiology, University of Saskatchewan (1989)

Residency in neuropathology, University of Toronto (1990-1993) (Fellow of the Royal College of Physicians and Surgeons of Canada in Neuropathology)

Post-doctorate in neurobiology, Université de Paris (INSERM U134, Hôpital de la Salpétrière) (1993-1994)

Awards

Manitoba Health Research Council Scholarship (1996-1999)

Rh Award for Outstanding Contributions to Scholarship and Research (1998)

Manitoba Medical Service Foundation Clinical Research Professorship (2001-2004)

Canada Research Chair in Developmental Neuropathology, Tier 1 (2004-2010, 2011-2017)

Robert H. Pudenz Award for Excellence in Cerebrospinal Fluid Physiology Research (2009)

Mentor of the Year, Royal College of Physicians and Surgeons of Canada (2014)

Fellow, Canadian Academy of Health Sciences (2017)

Contact us

Pathology
Max Rady College of Medicine
401 Brodie, 727 McDermot Avenue
University of Manitoba (Bannatyne campus)
Winnipeg, MB R3E 3P5 Canada

204-789-3212
204-789-3931