• Blank research profile image.
  • Associate professor

    Max Rady College of Medicine
    Internal Medicine
    University of Manitoba
    Room 312-777 William Avenue
    Winnipeg, Manitoba R3E 3R4

    Phone: 204-789-1125
    Fax: 204-789-1198
    chris.wiebe@umanitoba.ca

Cross appointments

Does not hold any cross appointments.

Research theme

  • Determinants of de novo donor-specific antibody development and rejection in kidney transplantation

Research interest

  • HLA molecular mismatch as a biomarker for precision medicine

Keywords

  • Kidney transplant
  • Rejection
  • Allograft survival
  • HLA mismatch

Research affiliations

  • Clinician scientist, Shared Health Manitoba (CHRIM)
  • Co-director, Transplant Immunology Laboratory, Diagnostic Services of Manitoba

Research summary

Dr. Wiebe has published on the clinical and pathologic risk factors for de novo donor-specific antibody development. He also has developed expertise in the quantification and identification of the HLA alloepitopes mismatched between donor and recipient HLA alleles and has published on the role these play as predictors of dnDSA development. Ongoing work investigates the potential for HLA molecular mismatch to serve as a predictive and prognostic biomarker in renal transplantation.

Biography

Dr. Wiebe is a transplant nephrologist and associate professor of internal medicine and immunology with expertise in immunogenetics and the development of de novo donor-specific antibodies in renal transplantation.

Education

Clinical Investigator Program, University of Manitoba (2014)

Masters of Immunology, University of Manitoba (2014)

Fellow, Royal College of Physicians and Surgeons of Canada (FRCPC), Nephrology (2010)

Fellow, Royal College of Physicians and Surgeons of Canada (FRCPC), Internal Medicine (2009)

Medical Doctor, Medical Licensing Counsel of Canada (2005)

Bachelor of Sciences in Medicine, University of Manitoba (2005)

Bachelor of Science, University of Manitoba (2001)

Awards

Liam J. Murphy Young Investigator Award, University of Manitoba (2018)

Aubie Angel Young Investigator Award in Clinical Research, University of Manitoba (2018)

MHRC Operating Grant, Manitoba Health Research Council (2014-2016)

AST Young Innovator Award, American Society of Transplantation (2013)

S.W. Prowse Memorial Award for Clinical Research, University of Manitoba (2013)

CST Fellows Top Abstract Presentation, Canadian Society of Transplantation (2013)

KRESCENT Post-Doctural Fellowship, Kidney Foundation of Canada, (2012-2014)

Faculty Development and Research Award, University of Manitoba (2010-2014)

MHRC Clinical Fellowship Award, Manitoba Health Research Council (2010-2012)

R. Samuel McLaughlin/MMSF Res. & Edu. Award, University of Manitoba, (2010-2012)

Mindel and Tom Olenick Research Award in Immunology, University of Manitoba (2010-2011)

Nicholas and Annie Dawyduk Scholarship, University of Manitoba (2004-2005)

Bachelor of Science in Medicine Stipend, University of Manitoba (2002-2003)

University of Manitoba Students’ Union Scholarship, University of Manitoba (1999-2002)

Contact us

Internal Medicine
Room GC430, Health Sciences Centre
820 Sherbrook Street
University of Manitoba
Winnipeg, MB R3A 1R9 Canada

204-787-7772
204-787-4826