Keywords

Research affiliations

Principal investigator, Neuroscience Research Program in Kleysen Institute for Advanced Medicine, Health Sciences Centre

Research summary

Dr. Jun-Feng Wang’s research program is to understand the role of oxidative stress and neuroinflammation in chronic stress, depression and Alzheimer’s disease.

His laboratory focuses on determining how oxidative protein modification and NLRP3 inflammasome activation affect brain synaptic functions, establishing whether thioredoxin antioxidant system inhibits chronic stress-induced oxidative stress and neuroinflammation, and improving chronic stress-induced depression and cognitive dysfunction.

Research techniques employed in his work include cell culturing, real time-PCR, DNA cloning, cell transfection, immunoblotting analysis, co-immunoprecipitation, immunohistochemistry, gene knock down and animal behavioural tests, among others.

Biography

Dr. Jun-Feng Wang is an professor of pharmacology and therapeutics. His research focuses on oxidative damage and neuroinflammtion in chronic stress, depression and Alzheimer’s disease. His research is supported by grants from the Natural Sciences and Engineering Research Council of Canada (NSERC), the Canadian Institutes of Health Research (CIHR) and Alzheimer Society of Canada. Previously Dr. Wang held academic appointments at the Centre for Addiction and Mental Health in Toronto, the University of Toronto and the University of British Columbia.

Education

ORCID profile

Visit Jun-Feng Wang's ORCID profile for a complete listing.

Jun-Feng Wang's profile

Contact us

Pharmacology and Therapeutics
Max Rady College of Medicine
A205 Chown Bldg., 753 McDermot Avenue
University of Manitoba (Bannatyne campus)
Winnipeg, MB R3E 0T6 Canada

204-789-3553