Max Rady College of Medicine
Biochemistry and Medical Genetics
Room 312 – 745 Bannatyne Avenue
University of Manitoba
Winnipeg, Manitoba R3E 0J9
Understanding what makes the human brain unique at a cellular and molecular level is the core focus of the Beattie lab. To address this, we investigate the molecular regulators of neural stem cell lineage progression and their role in determining cell types and states in the developing central nervous system. To study neural development at single-cell resolution, we apply Mosaic Analysis with Double Markers (MADM) technologies, a single-cell genetic approach for in vivo lineage tracing. We also use these tools to address questions involving childhood developmental disorders, including Autism Spectrum Disorder and neuropsychiatric disorders, including Schizophrenia.
Dr. Robert Beattie is an Assistant Professor of Biochemistry and Medical Genetics within the Rady Faculty of Health Sciences.
Dr. Beattie received his bachelor of science (honours co-op) in microbiology from the University of Manitoba (2009) and his PhD in Biomedical Sciences from The University of Sheffield, in England (2014). He completed postdoctoral training at the University of Basel, in Basel, Switzerland and the Institute of Science and Technology (IST) Austria, in Klosterneuburg, Austria. His research has helped to advance a dual colour, genetic lineage tracing technology called Mosaic Analysis with Double Markers (MADM), which he used to study the molecular regulators underlying stem cell fate decisions at single-cell resolution. Dr. Beattie joined the University of Manitoba as an assistant professor in August 2021.
Dr. Beattie currently applies MADM technologies to investigate how cell-intrinsic and tissue-wide gene programs contribute to normal brain development and tissue homeostasis.
Visit Robert Beattie's ORCID profile for a complete listing, or find him on Google Scholar.