• Jeffrey Wigle headshot
  • Professor

    Max Rady College of Medicine
    Biochemistry and Medical Genetics
    University of Manitoba
    Room R4011 – Institute of Cardiovascular Sciences
    St. Boniface Hospital Albrechtsen Research Centre
    351 Tache Avenue
    Winnipeg, Manitoba R2H 2A6

    Phone: 204-235-3953

Research summary

Dr. Jeffrey Wigle is a developmental biologist who is studying how homeobox transcription factors control cardiovascular function during both embryonic development and during disease progression. Since many of the growth pathways used by the growing fetal cardiovascular system are reutilized in adults during disease, we can better understand disease processes by determining the roles of transcription factors during embryonic development.


Brief bio

Dr. Jeffrey Wigle cloned and characterized a novel family of membrane proteins in his PhD work. During his postdoctoral fellowship, he determined that a gene, Prox1, was essential for the development of the lymphatic vessels in a mouse model. His current interests are in the transcriptional control of the process of cardiac fibrosis.


  • Postdoctoral fellowship, St. Jude Children’s Research Hospital, Memphis, Tennessee
  • PhD, department of pharmacology, University of Ottawa
  • Bachelor of Science (Honours), department of biochemistry, Queen’s University


  • Canadian Institutes of Health Research New Investigator Award
  • Research Manitoba Chair

Contact us

Biochemistry and Medical Genetics
Room 336 Basic Medical Sciences Building
745 Bannatyne Avenue
University of Manitoba
Winnipeg, MB R3E 0J9 Canada