The University of Manitoba campuses are located on original lands of Anishinaabeg, Cree, Ojibwe-Cree, Dakota, and Dene peoples, and on the National Homeland of the Red River Métis. More
University of Manitoba
Winnipeg, Manitoba Canada, R3T 2N2
Max Rady College of Medicine
Biochemistry and Medical Genetics
University of Manitoba
Room R4011 – Institute of Cardiovascular Sciences
St. Boniface Hospital Albrechtsen Research Centre
351 Tache Avenue
Winnipeg, Manitoba R2H 2A6
Phone: 204-235-3953
jeffrey.wigle@umanitoba.ca
Dr. Jeffrey Wigle is a developmental biologist who is studying how homeobox transcription factors control cardiovascular function during both embryonic development and during disease progression. Since many of the growth pathways used by the growing fetal cardiovascular system are reutilized in adults during disease, we can better understand disease processes by determining the roles of transcription factors during embryonic development.
Dr. Jeffrey Wigle cloned and characterized a novel family of membrane proteins in his PhD work. During his postdoctoral fellowship, he determined that a gene, Prox1, was essential for the development of the lymphatic vessels in a mouse model. His current interests are in the transcriptional control of the process of cardiac fibrosis.
Biochemistry and Medical Genetics
Room 336 Basic Medical Sciences Building
745 Bannatyne Avenue
University of Manitoba
Winnipeg, MB R3E 0J9 Canada
