• How does cellular calcium regulation change in Alzheimer’s Disease and diabetes?
• What are the mechanisms of synaptic plasticity and how do they translate into learning and memory?
• How is synaptic plasticity and its impact on animal behaviour altered in neurodegenerative disorders?
• What is the role of the DNA repair enzyme PARP in stroke and Multiple Sclerosis?
• What are the mechanisms of nerve degeneration in types 1 and 2 diabetes?
• How are adenine nucleotide levels regulated in normal brain and in cerebral ischemia?
• What is the structure and function of the blood brain barrier?
• How do astrocytes participate in synaptic function and cerebral blood flow regulation?
• What is the role of astrocyte D-serine in neuronal injury in stroke and trauma?
• Are adenosine receptors viable therapeutic targets for CNS inflammation in Multiple Sclerosis?
• Can MRI imaging protocols be developed for early diagnosis of Alzheimer’s Disease?

Faculty Involved: