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Name: Carla G. Taylor Position: Professor Office: Laboratory: Phone No.: (204) 474-8079 Fax No.: (204) 474-7593
E-mail: ctaylor@cc.umanitoba.ca
Research Interests: Diet and Insulin Resistance: Effects of dietary fatty acids (conjugated linoleic acid, omega-3) on insulin resistance, adipokines and adipose function. Insulin-mimetic properties of novel bioactive compounds in buckwheat. Nutrition, Antioxidant and Immune Defense: Effects of dietary zinc on T-lymphocyte development and zinc-finger proteins involved in cell signaling. Protective effects of zinc supplementation during inflammation and heavy metal toxicity. Selected Publications: Noto, A., Zahradka, P., Ryz, N.R., Yurkova, N., Xie, X., and Taylor , C.G. 2007 Conjugated linoleic acid (CLA) preserves pancreatic function and reduces inflammatory markers in obese insulin-resistant rats. Metabolism 56:142-151. Burr. L.L., Taylor , C.G., and Weiler, H.A. 2006 Conjugated linoleic acid isomers, cis -9, trans -11 and trans -10, cis -12, fed in combination have a greater effect on bone mass than single isomers in fa/fa and lean Zucker rats. Exp. Biol. Med. [in press]. Jamieson, J., Taylor , C.G., and Weiler, H.A. 2006 Marginal zinc deficiency exacerbates bone lead deposition and high dietary zinc attenuates lead deposition at the expense of bone density in growing rats. Toxicol. Sci. 92: 286-294. Noto, A., Zahradka, P., Yurkova, N., Xie, X., Nitschmann, E., Ogborn, M., and Taylor, C.G. 2006 Conjugated linoleic acid (CLA) reduces hepatic steatosis, improves liver function and favorably modifies lipid metabolism in obese insulin resistant rats. Lipids 41: 179-188. Zahradka, P., Wright, B., Fuerst, M., Yurkova, N., Molnar, K., and Taylor, C.G. 2006 Peroxisome proliferator-activated receptor (PPAR) a and ? ligands differentially affect smooth muscle cell proliferation and migration. J. Pharmacol. Exp. Ther. 317: 651-9. Taylor, C. G. 2005 Zinc, the pancreas, and diabetes: Insights from rodent studies and future directions. BioMetals 18: 305-312 . Mollard, R.C., Gillam, M. E., Wood, T. M., Taylor, C. G. , and Weiler, H. A. 2005 n-3 Fatty acids reduce the release of prostaglandin E 2 from bone but do not affect bone mass in obese ( fa/fa ) and lean Zucker rats. J. Nutr. 135: 499-504. Hosea H. J. , Rector E. S., and Taylor C. G. 2005 Age-related changes in p56 lck protein levels and phenotypic distribution of T lymphocytes in young rats. Clinical Dev. Immunol. 12(1):75-84. Taylor, C. G. and Zahradka, P. 2004 Dietary conjugated linoleic acid (CLA) and insulin sensitivity/resistance in rodent models. Am. J. Clin. Nutr. 79: 1164S-1168S. Hosea, H. J., and Taylor, C. G. 2004 Dietary repletion can replenish reduced T cell subset numbers and lymphoid organ weight in zinc-deficient and energy-restricted rats. Br. J. Nutr. 91: 741-747. Hosea, H. J., Taylor, C. G., Wood, T., Mollard, R., and Weiler, H. A. 2004 Zinc-deficient rats have more limited bone recovery during repletion than diet-restricted rats. Exp. Biol. Med. 229: 303-311. Hosea, H. J., Rector, E. S., and Taylor, C. G. 2003 Zinc-deficient rats have fewer recent thymic emigrant (CD90 + ) T lymphocytes in spleen and blood. J. Nutr. 133: 4239-42. Kawa, J. M., Przybylski, R., and Taylor, C. G. 2003 A buckwheat extract containing D- chiro -inositol lowers blood glucose in streptozotocin-treated rats. J. Agric. Food Chem. 51: 7287-7291. Kawa, J. M., Przybylski, R., and Taylor, C. G. 2003 Urinary D- chiro -inositol and myo -inositol excretion is elevated in the diabetic db/db mouse and streptozotocin-diabetic rat. Exp. Biol. Med. 128: 907-914. Zahradka, P., Yurkova, N., Litchie, B., Moon, M. C., Del Rizzo, D. F., and Taylor, C. G. 2003 Activation of peroxisome proliferator-activated receptors a and ?1 inhibits human smooth muscle cell proliferation. Mol. Cell. Biochem . 246: 105-110. Tallman, D. L, and Taylor, C. G. 2003 Effects of dietary fat and zinc on adiposity, serum leptin and adipose fatty acid composition in C57BL/6J mice. J. Nutr. Biochem. 14: 17-23.
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