Dr. Wen Zhong
 
Associate Professor
Department of Medical Microbiology, University of Manitoba
Degrees: B.E. 1996 China Textile University, PhD 2001 China Textile University, Postdoctoral associate, University of California, Davis 2002-2004
Address: H579 Duff Roblin Building, University of Manitoba, R3T 2N2, Canada

Phone: (204) 474-9913, Fax: (204) 474-7592

email: wen.zhong@umanitoba.ca

Research Interests:

  • Nanofibers/nanoparticles for targeted drug delivery
  • Functional nanofibers for biomedical end uses
  • Trans-dermal drug delivery
  • Transport behavior of fibrous/biomedical materials
  • Biodegradable polymers

Research Supported By: 

  • NSERC (Natural Sciences and Engineering Research Council of Canada) Discovery
  • NSERC RTI (Research Tools and Instrument)
  • CFI (Canada Foundation for Innovation)
  • MHRC (Manitoba Health Research Council)
  • MMSF (Manitoba Medical Service Foundation)
  • URGP (University Research Grant Program)
  • Faculty of Human Ecology Startup funds and Research Associate funds

Award:
  -  2011 Rh Award in Natural Sciences from the Winnipeg Rh Foundation

Recent Publications and Journals Articles:

Chen, J., Qiu, X., Wang, L., Zhong, W., Kong, J., and Xing M. (2014). Free‐Standing Cell Sheet Assembled with Ultrathin Extracellular Matrix as an Innovative Approach for Biomimetic Tissues. Advanced Functional Materials, DOI: 10.1002/adfm.201302949.

Chen, J., Shi, M., Liu P., Ko, A., Zhong, W., Liao W., and Xing, M. (2014). Reducible polyamidoamine-magnetic iron oxide self-assembled nanoparticles for doxorubicin delivery. Biomaterials, 35: 1240-1248.

Tian, Y., Glogowska, A., Zhong, W., Klonisch, T., and Xing, M. (2013). Polymeric mesoporous silica nanoparticles as a pH-responsive switch to control doxorubicin intracellular delivery.  Journal of Materials Chemistry B, 1: 5264-5272.

Chen, J., Ouyang, J., Kong, J., Zhong, W., Xing, M. (2013). Photo-crosslinked and pH sensitive biodegradable micelles for doxorubicin delivery. ACS applied Materials & Interfaces, 5: 3108-3117. 

Baker, M.L., Chen, Y., Laguë, C., Landry, H., Peng, Q. and Zhong W. (2013). Fiber Yield and Energy Requirement of Hew Decortication Using a Hammermill. Applied Engineering in Agriculture, 29:453-460.

Khan, M. M. R., Chen, Y., Laguë, C., Landry, H., Peng, Q. and Zhong W. (2013). Hemp decortication using the drop weight method. Applied Engineering in Agriculture, 29: 79-87.

Guzman, L., Chen, Y., Potter, S., Zhong, W., and Rahman, M, (2013). Application of stochastic modelling for simulating hemp fibre peeling behavior. Canadian Biosystem Engineering, 55: 21-28.

Shi, J. B., Ouyang, J., Li, Q. T., Wang, L.Y., Wu, J., Zhong, W. and Xing, M.

(2012). Cell-compatible hydrogels based on a multifunctional crosslinker with tunable stiffness for tissue engineering. Journal of Materials Chemistry, 22: 23952-23962.

Chen, J., Zehtabi, F., Ouyang, J., Kong, JM, Zhong, W. and Xing, M. (2012). Reducible self-assembled micelles for enhanced intracellular delivery of doxorubicin. Journal of Materials Chemistry, 22(15): 7121-7129. (Featured on the front cover of Issue 15)

Shi, J. B., Xing, M. and Zhong, W. (2012). Development of Hydrogels and Biomimetic Regulators as Tissue Engineering Scaffold. Membranes, 2:70-90.

Chen, J., Zhou, S., Li, Q., Ouyang, J., Kong, J., Zhong, W. and Xing, M. (2011). PLLA-PEG-TCH –labeled Bioactive Molecule Nanofibers for Tissue Engineering. International Journal of Nanomedicine, 6: 2533-2542.

Chen, J., Qiu, X., Ouyang, J., Kong, J., Zhong, W. and Xing, M. (2011). pH and Reduction Dual-Sensitive Copolymeric Micelles for Intracellular Doxorubicin Delivery. Biomacromolecules, 12 (10), 3601-3611 (Top 2 most read and downloaded articles on Oct 2011).

Chen, J., Xing, M. and Zhong, W. (2011).

Degradable micelles based on hydrolytically degradable amphiphilic graft copolymers for doxorubicin delivery. Polymer, 52(4), 933-941.

Xing, M., & Zhong, W. (2011). Shell cross-linked and hepatocyte-targeting nanoparticles containing doxorubicin via acid-cleavable linkage. Nanomedicine: Nanotechnology, Biology and Medicine, 7(1), 80-87.

Khan, M.M.R., Chen, Y., Belsham, T., Lague, C., Landry, H., Peng, Q., Zhong, W. (2011). Fineness and tensile properties of hemp (Cannabis sativa L.) fibres. Biosystem Engineering, 108, 9-17.

Xing, M., Zhong, W., Xu, X.L., & Thomson, D. (2010). Adhesion force studies of nanofibers and nanoparticles. Langmuir, 26, 11809-11814. 

Lu, C.H., & Zhong, W. (2010).

Synthesis of Propargyl-terminated Heterobifunctional Poly(ethylene glycol). Polymers, 2, 407-417.

Zhong, W., Xing, M.M.Q., & Maibach, H.I. (2010). Nanofibrous Mateirals for Wound Care. Cutaneous and Ocular Toxicology, 29, 143-152.

Xu, X.L., Zhong, W., Zhou, S.F., Trajtman, A., & Alfa, M. (2010). Electrospun PEG-PLA Nanofibrous Membrane for Sustained Release of Hydrophilic Antibiotics. Journal of Applied Polymer Sciences, 118, 588-595.

Zhou, S. & Zhong, W. (2010). Adhesion and Binding in Nanofibrous Materials. Journal of Adhesion Science and Technology, 24, 35-44.

Khan, M.R., Chen, Y., Lague, C., Landry, H., Peng, Q., & Zhong, W. (2010). Compressive properties of Hemp (Cannabis sativa L.) stalks. Biosystems Engineering, 106, 315-323.

Book/Monograph
1.  Zhong W. An introduction to Healthcare and Medical Textiles, Lancaster, PA: DEStech Publications, Inc., 2012.