Demitre Serletis
Dr. Serletis completed his B.Sc. and M.D. training at the University of Calgary. He then completed his Neurosurgery residency training at the University of Toronto, where he also completed his Ph.D. graduate studies in Physiology and Biomedical Engineering. Dr. Serletis went on to complete a prestigious fellowship in Epilepsy Neurosurgery at the Cleveland Clinic (Ohio). Subsequently, he assumed a position as Assistant Professor of Neurosurgery at the University of Arkansas for Medical Sciences (UAMS) in Little Rock, where he worked for over 3 years.

Dr. Serletis joined the Departments of Surgery and Pediatrics as a member of the Section of Neurosurgery in April 2016. His clinical specialties are in Epilepsy and Pediatric Neurosurgery. He is presently the Director of Epilepsy Surgery, and is also a Scientist at the Children’s Hospital Research Institute of Manitoba (CHRIM), where he currently directs the Manitoba Neurosurgery Laboratory.

Research Focus
Dr. Serletis’ lab focuses on the neuroengineering study of biosignals acquired in vivo from the human brain, including EEG and MRI-based signals, during the standard work-up of epilepsy patients with medically refractory seizures. Neuroengineering techniques drawing on nonlinear dynamics, complexity theory and fractal methods offer innovative strategies to the study of extra- and intra-cranial human EEG brain recordings, and may be used to identify novel mathematical markers underlying the transition to the epileptic state, with monitoring and/or therapeutic implications.

Dr. Serletis also holds diverse research interests in the study of neural networks servicing language, memory and other cognitive functions, that lend themselves to further study with intracranial electrodes. By combining improved imaging capabilities and intracranial EEG recordings, there is a wealth of knowledge to be gained in enhancing the understanding and characterization of 3D networks within the brain. Future research interests include virtual reality and simulation for educational purposes.

1. McKenzie, M.B., M.-L. Jones, A. O’Carroll, D. Serletis and M.C. Ng. “Breakthrough Spikes in Rapid Eye Movement Sleep from the Epilepsy Monitoring Unit are associated with Peak Seizure Frequency.” Sleep. 2020. Epub, doi: 10.1093/sleep/zsz281.

2. Ajisebutu, A., M. R. Del Bigio, C.J. Kazina, M. West and D. Serletis. “Dr. Dwight Parkinson: A Canadian Neurosurgical Pioneer.” Journal of Neurosurgery. 2019. Epub, doi: 10.3171/2019.6.JNS19262.

3. Del Bigio, M., R.K. Sidhu, C.J. Kazina and D. Serletis. “Inflammation and Obstruction of Distal Catheter Slits in Ventriculoperitoneal Shunts: Likely Role of Graphite.” Journal of Neurosurgery. 2019. Epub, doi: 10.3171/2019.6.JNS191082.

4. Almojuela A., M.C. Honey, A. Gomez, M. Hasen, C. MacDonald, C. Kazina and D. Serletis. “Novel Use of Fluorescein Sodium in the Resection of a Pediatric Posterior Fossa Tumor.” Canadian Journal of Neurological Sciences. 2020. 47:578-580.

5. Narayanasamy G., S. Morrill, D. Cousins, J. Liu, G. Deshazer, W. Garner, E. Galhardo, D. Serletis and J. Penagaricano. “Radiosurgery for Mesial Temporal Lobe Epilepsy following ROSE Trial Guidelines – A Planning Comparison Between Gamma Knife, Eclipse and Brainlab.” Journal of Applied Clinical Medical Physics. 2019. 20:134-141.

University of Manitoba
Associate Professor - Department of Surgery and Department of Pediatrics

Cross or adjunct appointments with other Departments
Department of Biomedical Engineering, Faculty of Engineering
Department of Physiology & Pathophysiology

Current Position
Pediatric Neurosurgeon
Department of Surgery
Children's Hospital - Health Sciences

Association with a Research Institute
Children's Hospital Research Institute of Manitoba (CHRIM)


Dr. Demitre Serletis
GB1 - 820 Sherbrook Street
Health Sciences Centre
Winnipeg Manitoba
Canada R3A 1R9

Phone:   (204) 787-7221
Fax:       (204) 787-3851

Notice to potential students
Currently accepting students