Dr. Pam Orr
Professor,Departments of Medicine(Section of Infectious Diseases), Medical Microbiology and Community Health Sciences
 Degrees:  MD (Univ. of Toronto) 1974-79, FRCPC Internal Medicine (Univ. of Manitoba) 1984-88
Specialist Certification in Infectious Disease (RCPSC)(Univ. of Manitoba) 1987-89
Masterof Science, Department of Community Health Sciences (Univ. of Manitoba) 1989-94
Mailing Address: Health Sciences Centre
GC 443 -820 Sherbrook St.
Winnipeg, Manitoba, Canada, R3A 1R9

Tel:  (204) 787-7029
Fax: (204) 787-4826
email: porr@hsc.mb.ca
Research Interests:
Research focuses on indigenous and circumpolar health with special interest in infectious diseases, the social determinants of health and health care delivery, health and justice

Recent Publications In Peer Reviewed Journals:

For a list of Dr. Orr's PubMed articles, please click here

Publications 2015-2020:

Larcombe, L., Mookherjee, N., Slater, J., Slivinski, C., Dantouze, J., Singer, M., Whaley, C., Denechezhe, L., Matyas, S., Decter, K., Turner-Brannen, E., Ramsey, C., Nickerson, P., & Orr, P. (2015). Vitamin D, serum 25(OH)D, LL-37 and polymorphisms in a Canadian First Nation population with endemic tuberculosis. International Journal of Circumpolar Health, 74. doi:http://dx.doi.org/10.3402/ijch.v74.28952

Larcombe L, Mookherjee N, Lodge A, Brown J, Denechezhe L, Nickerson P, Orr P. Frequency of NRAMP1 gene polymorphisms among  in Canadian First Nations peoples experiencing endemic tuberculosis. Mycobacterial Diseases, 2015, 5:193. Available at: http://dx.doi.org/10.4172/2161-1068.1000193.

Apter D, Wheeler CM, Paavonen et al, and the HPV PATRICIA Study Group (includes P. Orr). Efficacy of Human Papilloma 16 and 18 (HPV-16/18) AS04 Adjuvanted Vaccine against Cervical Infection and Precancer in Young Women: Final Event-Driven Analysis of the Randomized, Double-Blind PATRICIA Trial. Clinical and Vaccine Immunology, 2015; 22(4), 361-373.

Gnann JW, Skoldenberg B, Hart J et al, and the National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group (includes P. Orr). Herpes Simplex Encephalitis: Lack of Clinical Benefit of Long-term Valacyclovir Therapy. Clinical Infectious Diseases. 2015; 61: 683-691.

Kiazyk, Sandra, Larcombe, Linda, Lopez, Carmen, Matyas, Sara, Mesa, Christine , Orr, Pamela , Sharma, Meenu; Juno , Jennifer , Waruk, Jillian , Ball, T. Blake. IFN-γ promoter polymorphisms do not affect QuantiFERON® TB Gold In-Tube test results in a Canadian population.  International Journal of Tuberculosis and Lung Disease 2016; 20(12): 1647-1652.

HLA- A, B, DRB1, DQA1, DQB1 alleles and haplotype frequencies in Dene and Cree cohorts in Manitoba. Linda A. Larcombe, Peter W. Nickerson, Andrew M. Lodge, Jodie S. Brown, Leisel C. Milligan, Denise Pochinco, Lynnette Beaudin, Brian Arundel, Jacqueline Wong, Joe Dantouze, Lizette Denechezhe, Leo Dettanikkezhe, Pamela H. Orr. Human Immunology. 2017, http://dx.doi.org/10.1016/j.humimm.2017.03.009.

Abonyi S, Mayan M, Boffa J, Lopez C, McMullin K, Heffernan C, Hoeppner V, King M, Orr P, Long R. “Finally when I started falling down”: Indigenous TB Patient Experiences of health and illness on the Canadian Prairies. International Journal of Indigenous Health, 2017;12: 1.

Patel S, Paulsen C, Heffernan C, Saunders D, Sharma M, King M, Hoeppner V, Orr P, Kunimoto D, Menzies D, Christianson S, Wolfe J, Boffa J, McMullin K, Lopez-Hille C, Senthilselvan A, Long R. Tuberculosis transmission in the Indigenous peoples of the Canadian prairies. PLoS One, November 14, 2017. Available at: https://doi.org/10.1371/journal.pone.0188189

A performance measures analysis of a Canadian provincial tuberculosis (TB) program: Manitoba 2008-2012. Basham CA, Elias B, Fanning A, Orr P. International Journal of Tuberculosis and Lung Disease, 2018; 22(4).

Disseminated Mycobacterium bovis infection post kidney transplant. Ziegler J, Ho J, Gibson I, Nayak J, Stein M, Storsley L, Walkty A, Orr P. Transplant Infectious Disease, May 2018

Dene First Nation Community Readiness to take action against HIV/AIDS. Larcombe L, McLeod A, Samuel S, Samuel J, Payne M, Van Haute S, Singer M, Ringaert L, Meyers A, Maching R, Kinew K, Keynan Y, MacDonald K, Antsanen J, Orr P. International Journal for Circumpolar Health.  December 2019, VOL. 781588092https://doi.org/10.1080/22423982.2019.1588092

Tuberculosis among Northern Manitoba First Nations, 2008-2012: Program performance on- and off-reserve. Basham CA, Elias B, Fanning A, Orr P. Canadian Journal of Public Health July 2019; https://doi.org/10.17269/s41997-019-00231-2.

Polymorphisms in the P2X7 receptor, and differential expression of Toll-like receptor-mediated cytokines and defensins, in a Canadian Indigenous group. Semple C, Choi K-YG, Kroeker A, Denechezhe L, Orr P, Mookherjee N, Larcombe L. Scientific Reports, October 2019,9:14204.

Sekuwe (My House): Building Health Equity through Dene First Nations Housing Designs. Larcombe L, Coar L, Singer M, Denechezhe L, Yassi E, Kinew K, Orr P.  IJCH, January 2020:79:1; https://doi.org/10.1080/22423982.2020.1717278


1. Sekuwe: My House. Dene First Nations Perspectives on Health Homes. Editors: L. Larcombe, L. Coar. Collaborators: Denechezhe L, Yassie E, Singer M, Kinew K, Orr P. Friesen Press, 2016



  • Vice-President, Circumpolar Health Research Network
  • Associate Editor, International Journal of Circumpolar Health
  • Associate Head-Education, Department of Internal Medicine, University of Manitoba
  • Board Member, International Union Against Tuberculosis and Lung Disease
  • Past President, International Union for Circumpolar Health, Canadian Society for Circumpolar
  • Health, North American Region of the International Union Against Tuberculosis and Lung Disease