Dr. Nadon’s laboratory is focused on the design and delivery of national and international laboratory-based surveillance and outbreak response for enteric diseases, including Salmonella, E. coli, Shigella, Campylobacter, Listeria, and Vibrio. Her laboratory is responsible for the operation of PulseNet Canada, the national real-time surveillance system for foodborne disease in Canada that is based exclusively on whole genome sequencing. Her laboratory’s work is centered on the interface between laboratory and epidemiology for optimum delivery of public health. Current activities are focused on these areas:
- Genomic epidemiology of current and emerging bacterial enteric pathogens, including V. cholerae
- Design and implementation of global surveillance systems using genomics
- Utilization and analysis of genomic data for surveillance outside of traditional point source outbreak detection
Dr. Nadon is also keenly interested in science literacy and communication; her work also focuses on developing and using effective communications strategies to better engage with colleagues, non-scientists, and the public.
Selected Recent Nadon Lab Publications:
Rumore J, Tschetter L, Kearney A, Kandar R, McCormick R, Walker M, Peterson CL, Reimer A, Nadon C. 2018. Evaluation of whole-genome sequencing for outbreak detection of Verotoxigenic Escherichia coli O157:H7 from the Canadian perspective. BMC Genomics. 2018 Dec 4;19(1):870.
Nadon C, Van Walle I, Gerner-Smidt P, Campos J, Chinen I, Concepcion-Acevedo J, Gilpin B, Smith AM, Man Kam K, Perez E, Trees E, Kubota K, Takkinen J, Nielsen EM, Carleton H; FWD-NEXT Expert Panel. 2017. PulseNet International: Vision for the implementation of whole genome sequencing (WGS) for global food-borne disease surveillance. Euro Surveill. 2017 Jun 8;22(23).
Yachison CA, Yoshida C, Robertson J, Nash JHE, Kruczkiewicz P, Taboada EN, Walker M, Reimer A, Christianson S, Nichani A; PulseNet Canada Steering Committee, Nadon C. 2017. The Validation and Implications of Using Whole Genome Sequencing as a Replacement for Traditional Serotyping for a National Salmonella Reference Laboratory. Front Microbiol. 2017 Jun 9;8:1044.
Gilmour, M.W, M. Graham, G. Van Domselaar, S. Tyler, H. Kent, K. Trout-Yakel, O. Larios,
V. Allen, B. Lee, and C. Nadon. 2010. High-throughput genome sequencing of two Listeria
monocytogenes clinical isolates during a large foodborne outbreak. BMC Genomics. 2010
International Working Group Reports
Whole genome sequencing for foodborne disease surveillance: Landscape paper
Applications of Whole Genome Sequencing (WGS) in food safety management
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