Dr. Alberto Severini

Assistant Professor, Medical Microbiology and Infectious Diseases.
Assistant Professor, Faculty of Pharmacy,
Chief, Viral Exanthemata and STD Section, National Microbiology Laboratory, Public Health Agency of Canada

Degrees: M.D., 1981 (Parma , Italy); Biochemistry and Clinical Chemistry, 1987
(Parma , Italy).

Mailing Address:  Canadian Science Centre for Human and Animal Health 1015 Arlington Street, Winnipeg , MB , R3E 3R2

Tel: (204) 789-6022; Fax: (204) 789-2140; Lab: (204)789-6024
E-mail: Alberto.Severini@canada.ca

Dr. Severini is not currently accepting graduate students (Sept 2018)

Research Interests:
Human papillomavirus testing and molecular epidemiology. Viral molecular diagnostics. Whole genome sequencing and surveillance of measles, mumps and rubella.  Genomics of herpesviruses. Herpesvirus replication and pathogenesis mechanisms.

Recent Publications:

For a list of Dr. Severini's publications, please click here

1. No authors listed - The role of extended and whole genome sequencing for tracking transmission of measles and rubella viruses: report from the Global Measles and Rubella Laboratory Network meeting, 2017.. Weekly Epidemiol Record. 2018; 93:55-59.
2. Guerra FM, Crowcroft NS, Friedman L, Deeks SL, Halperin SA, Severini A, Hatchette TF, Shelly Bolotin S, on behalf of the Immunity of Canadians and Risk of Epidemics (iCARE) Network.Waning of measles maternal antibody in infants in measles elimination settings- A systematic literature review. Vaccine. 2018; 36:1248-1255.
3. Thomas S, Hiebert J, Gubbay JB, Gournis E, Sharron J, Severini A, Jiaravuthisan M, Shane A, Jaeger V, Crowcroft NS, Fediurek J, Sander B, Mazzulli T, Schulz H, Deeks SL. Measles Outbreak with Unique Virus Genotyping, Ontario, Canada, 2015. Emerg Infect Dis. 2017; 23:1063-1069.
4. Awua AK, Adanu RMK, Wiredu EK, Afari EA, Severini A. Differences in age-specific HPV prevalence between self-collected and health personnel collected specimen in a cross-sectional study in Ghana. Infect Agent Cancer. 2017;12:26. doi: 10.1186/s13027-017-0136-728529541.
5. Zehbe I, Jackson R, Wood B, Weaver B, Escott N, Severini A, Krajden M, Bishop L, Morrisseau K, Ogilvie G, Burchell AN, Little J. Community-randomised controlled trial embedded in the Anishinaabek Cervical Cancer Screening Study: human papillomavirus self-sampling versus Papanicolaou cytology. BMJ Open. 2016 Oct 8;6(10):e011754. doi: 10.1136/bmjopen-2016-011754.
6. Binkhamis K, Gillis H, Lafreniere JD, Hiebert J, Mendoza L, Pettipas J, Severini A, Hatchette TF, LeBlanc JJ. Comparison of monoplex and duplex RT-PCR assays for the detection of measles virus.  J Virol Methods. 2017;239:58-60.
7. Roy F, Mendoza L, Hiebert J, McNall RJ, Bankamp B, Connolly S, Lüdde A, Friedrich N, Mankertz A, Rota PA, Severini A. Rapid identification of measles virus vaccine genotypes by real time PCR. J Clin Microbiol. 2016; 55:735-743.
8. Hatchette TF, Scholz H, Bolotin S, Crowcroft NS, Jackson C, McLachlan E, Severini A; Immunity of Canadians and Risk of Epidemics (iCARE) laboratory group and the Canadian Immunization Research Network (CIRN). Calibration and Evaluation of quantitative antibody titers for measles virus using the BioPlex 2200.  Clin Vaccine Immunol. 2017; 24: pii: e00269-16.
9. Charlton CL and  Severini A. (2016) Current Dilemmas and pitfalls in rubella laboratory diagnostics in low prevalence or elimination settings. Curr Treat  Options  Infect Dis. 2016; DOI 10.1007/s40506-016-0090-8.
10. Berard AR, Severini A, Coombs KM. Differential Reovirus-Specific an Herpesvirus-Specific Activator Protein 1 Activation of Secretogranin II Leads to Altered Virus Secretion. J Virol. 2015; 89:11954-64.
11. De Serres G, Desai S, Shane A, Hiebert J, Ouakki M, Severini A. Measles In Canada Between 2002 and 2013.Open Forum Infect Dis.2015; 2: ofv048.
12. Berard AR, Severini A, Coombs KM. Comparative proteomic analyses of two reovirus T3D subtypes and comparison to T1L identifies multiple novel proteins in key cellular pathogenic pathways.Proteomics. 2015; 5:2113-35.
13. Berard AR, Coombs KM, Severini A. (. (2015). Quantification of the host response proteome after herpes simplex virus type 1 infection.J Proteome Res.14: 2121-42.
14. Totten S, MacLean R, Payne E, Severini A. Chlamydia and lymphogranuloma venereum in Canada: 2003-2012 Summary Report.Canada Communicable Disease Report. 2015;41(02)

Laboratory Members:

Jennifer Beirnes Technician Jennifer.Beirnes@canada.ca
Kerry Dust Grad Student dustk@myumanitoba.ca
Jasmine Frost     Grad Student Jasmine.frost@canada.ca


Suzanne Gibbons Biologist suzanne.boudreau@canada.ca
Joanne Hiebert Biologist joanne.hiebert@canada.ca
Dr. Elizabeth McLachlan Biologist elizabeth.mclachlan@canada.ca
Lillian Mendoza Technician lillian.mendoza@canada.ca
Helene Schulz Grad Student helene.schulz@canada.ca
Sarah Tohme Technician on leave
Robyn Thorington Grad Student robyn.thorington@canada.ca


Micah Venus Technician micah.venus@canada.ca


Jonathan Walker Technician jonathan.walker@canada.ca


Vanessa Zubach Technician on leave