Dr. James (Jim) Davie
 Headshot image of Jim Davie

Distinguished Professor, Department of Biochemistry and Medical Genetics
Senior Scientist, Research Institute in Oncology and Hematology
Director, Manitoba Epigenetic Network
General Secretary, Canadian Society for Molecular Biosciences
Co-Editor-in-Chief, Biochemistry and Cell Biology
Board of Directors, Canadian Science Publishing
 
Fellow, Royal Society of Canada
Fellow, Canadian Academy of Health Sciences

 
My research interests include epigenetic regulation of gene expression in normal and diseased cells, signal transduction pathways, and biomarkers in the detection of disease. My research program explores the role of chromatin modifiers in regulating gene expression. My early work reported that butyrate was a histone deacetylase inhibitor which arrested cancer cell proliferation. My current research program explores the mechanisms by which epigenetic modifiers (protein arginine methyltransferases, PRMTs) and histone modifications regulate the chromatin structure and expression of transcribed genes.

Biosketch

Contact Information:
204.272.3174
333A Basic Medical Science Building
Jim.Davie@umanitoba.ca
website