Research Groups

Dr. Mario Bieringer

Our research focuses on the preparation of novel inorganic solids and the investigation of their physical properties in an attempt to establish structure-property relationships. The materials of concern belong to the groups of transition metal oxides, lanthanide oxides and metal oxychlorides. The investigation of physical properties, crystallographic structures and electronic structures allows the identification of structure-property relationships in solids.
Website: Bieringer Group

Dr. Rebecca Davis

Research in the Davis group focuses on exploring of the mechanisms of asymmetric organocatalytic reactions and broadening the range of organic reactions in which asymmetric organocatalysis can be applied. To accomplish these tasks, we employ a combination of computational, kinetic and synthetic techniques to study and develop organocatalytic and metal-organo cooperative catalytic reactions.
Website: Davis Group

Dr. Kathleen Gough

My primary research focus is spectrochemical imaging of heterogeneous samples, from biological tissues (Alzheimer disease brain, stressed tendons) to diatoms and composite polymers. We use both FTIR microscopy, with Focal Plane Array, and Raman Microscopy. Image at left shows a senile plaque in AD brain, ~20 microns diameter, imaged with FTIR, at 1 micron pixel resolution.
Website: Gough Group

Dr. David Herbert

Research in the Herbert group focuses on constructing novel inorganic and organometallic compounds for use in energy and environmental applications. Taking our inspiration from nature, we try to design molecules that can enable cooperation between ligands and metals, or between different reactive sites, to facilitate challenging transformations and catalysis.
Website: Herbert Group

Dr. Philip Hultin

We are interested in synthetic method development. We have recently been pursuing a simple modular strategy to construct benzo[b]furans, indoles, benzo[b]thianes and related heterocycles. The concept is based on the ability to selectively functionalize the two C-Cl bonds and the C-H bond in adducts of trichloroethylene.
Website: Hultin Group

Dr. Mazdak Khajehpour

The Khajehpour group studies interactions that cause proteins to fold correctly. Folding processes in proteins are studied both from kinetic and thermodynamic standpoint. The techniques used in these studies are steady-state and time-resolved fluorescence spectroscopy, differential scanning calorimetry, stopped-flow and temperature-jump relaxation spectroscopy.

Dr. Scott Kroeker

Research in our group involves the structural investigation of inorganic and organometallic materials. The principal method of characterization is nuclear magnetic resonance (NMR). As many of the materials of interest contain nuclei with quadrupole moments, substantial efforts are devoted to the development of NMR techniques designed to probe such systems.
Website: Kroeker Group

Dr. Sean McKenna

We study the structural and molecular biology of protein-nucleic acid interactions. We are focused on understanding (i) the role of RNA-protein interactions in mediating the host cell immune response to viral infection, and (ii) investigating RNA quadruplex structures and their interactions with quadruplex-specific helicases.
Website: McKenna Group

Dr. Victor Nemykin
VNemykinWe study
the development of new organometallic porphyrins and analogues and understanding of their electron-transfer and light-harvesting properties. We are interested in: (i) the fundamental understanding and improvement of structure, reactivity, and electronic interactions in complex redox-active porphyrinoid-based arrays, (ii) the search for aromatic macrocycles useful for applications in molecular electronics, light-harvesting, catalysis, and photocatalysis; (iii) the creation of new methodologies for preparation of porphyrins and their analogues with useful properties.
Website: Nemykin Group
Dr. Joe O'Neil
Proteins carry out their biological functions through changes in conformation. We measure protein dynamics by NMR spectroscopy and hydrogen exchange chemistry to determine the timescale and magnitude of the conformational changes that explain the activities of a membrane protein, an HIV transcription activator and a viral enzyme.
Website: O'Neil Group
Dr. Hélène Perreault
Our laboratory uses mass spectrometry, especially matrix-assisted laser desorption/ionization (MALDI), to study the composition and structure of proteins, glycoproteins and oligosaccharides. Glycans found in antibodies are a main focus area and for these we develop sample preparation techniques using pull down, chromatography and electrophoresis to make samples amenable to mass spectrometry. We also use electrospray ionization (ESI-MS).
Website: Perreault Group

Dr. Frank Schweizer

The focus of our research is in Medicinal Chemistry. In particular, we are interested in carbohydrate-based antibacterials, antitumor agents and compounds involved in immunomodulation. In collaboration with researchers at the Faculty of Health Sciences, we are exploring the biological properties, toxicity and modes of action of our lead structures. The ultimate goal is to identify drug candidates worthy for validation in clinical trials.
Website: Schweizer Group

Dr. H. Georg Schreckenbach
Dr. Schreckenbach’s research interests are in the area of theoretical and computational chemistry, with a focus on the development and application of density functional theory (DFT) and other methods. Current research areas include actinide chemistry, environmental chemistry of Hg and other metals, solar energy (dye sensitized solar cells), polymer-based electronic devices, amongst others.
Website: Schreckenbach Group
Dr. John Sorensen The Sorensen group has an ongoing research program that is focused on the biosynthesis of natural products. Our main interest is the biosynthesis of polyketide natural products in lichen and other fungi. We are also examining the biosynthesis of novel natural products in soil fungi. We have other projects aimed at the synthesis of small molecules with biological applications.
Website: Sorensen Group
Dr. Gregg Tomy Research in the Tomy group focuses on developing analytical methods to measure chemicals used in commerce that have the potential to be persistent, bioaccumulative and toxic. We use high resolution mass spectrometry to unearth previously unreported chemicals in the environment.

Dr. Jörg Stetfeld

The primary goal of our research is to understand in detail the structure-function relationship of proteins as dynamic systems. We are mainly focused on signaling linked to catalytic turnover, the storage function of coiled-coil domains and mechanisms of complex formations and signal transduction within the extracellular matrix.
Website: Stetfeld Group

Dr. Jennifer van Wijngaarden High resolution molecular spectroscopy and ab initio calculations are used to probe the lowest energy states of reactive species to gain better understanding of their structures and dynamics. The lab is equipped with custom-built, state-of-the-art microwave spectrometers and group members are also actively involved in infrared experiments at the Canadian Light Source synchrotron facility.
Website: van Wijngaarden Group