Manitoba Breast Tumor Bank Fee Schedule 
Product Cost to Academic Users
Individual Cases
Case fee $ 10 (C cases) $ 20 (B cases) $ 30 (A cases) per case fee for baseline clinical-pathology data (ie histological composition, type, grade, size, ER/PR & nodal status,)
Paraffin 5µm sections $1 $1/section for up to 5 sections ($2/section for additional sections)
Frozen 5µm sections $2 $2/section for up to 5 sections, ($4 for additional sections). Double cost for twenty micron sections.
Clinical data $ 10 Add $ 2/yr followup. For the extended clinical data per case (treatment and outcome data)
     
Tissue Arrays    
Array case fee $20 per case fee for baseline clinical-pathology data (ie, type, grade, size, ER/PR & nodal status,)
Array 5µm section $100 / $200 $100/section for up to 5 five micron sections when clinical data is utilized $200/section for up to 5 five micron sections when clinical data is not utilized
Clinical data $10 For the extended clinical data per case (treatment and outcome data)

FOOTNOTES:

  • The philosophy of the MBTB dictates that tissue is only released in the form of thin sections (5-20um) to ensure amortization of each tissue block across multiple projects. Tissue arrays will be available in the near future. Note that the per cases fee differs between cases in different categories.

  • Examples of costs based on two hypothetical projects;
    - 100 C category cases for IHC with x 4 antibodies (on x 4 paraffin sections per case) and RT-PCR (on RNA extracted from x5 frozen sections per case) would cost; 100 cases @ x$10 per case fee ($1,000) + 100 x 4 paraffin sections @ $1/section ($ 400) + 100 x 5 frozen sections @ $2/section ($800) = $2,200 (+ reagents & shipping costs)
    - 100 B category cases for IHC with x 4 antibodies (on x 4 paraffin sections per case) and RT-PCR (on RNA extracted from x5 frozen sections per case) with a minimum of 3 yrs clinical follow-up data per case would cost; 100 cases @ x $20 per case fee ($2,000) + 100 x 4 paraffin sections @ $1/section ($ 400) + 100 x 5 frozen sections @ $2/section ($800) + 100 cases @ $10 + 3 x $2 followup data ($1,600) = $ 3,200 Tissue costs + $1,600 Data costs = $4,800 (+ reagents & shipping costs)

  • Supplies & Reagents: Additional charges would be applied on a cost recovery basis to cover the cost of specific reagents used for individual projects (eg special tubes, coated IHC slides etc) and these are available on request

  • Shipping: charges for shipping (usually by Fed-Ex) will vary by location and nature of the tissue batches. Note that although a single shipment would be cheaper, it is our policy to ship large case cohorts in several shipments for logistical and security reasons.

  • Arrays. The MBTB has recently begun to construct tissue arrays and has completed construction of two 0.6 mm duplicate core invasive tumor arrays (n=90 cases and n=165 cases). All cases are ER-ve invasive tumors. The cost of these arrays reflects the underlying value and input into each case (matching frozen blocks available, uniform pathology data, clinical outcome data available).

 


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© MICB & CSDB 2004
Revised Friday, May 28, 2004