Spectroscopy Research

Dr. Kathleen Gough

My primary research focus is spectrochemical imaging of heterogeneous samples, from biological tissues (Alzheimer disease brain, stressed tendons) to diatoms and composite polymers. We use both FTIR microscopy, with Focal Plane Array, and Raman Microscopy. Image at left shows a senile plaque in AD brain, ~20 microns diameter, imaged with FTIR, at 1 micron pixel resolution.
Website: Gough Group

Dr. Mazdak Khajehpour

The Khajehpour group studies interactions that cause proteins to fold correctly. Folding processes in proteins are studied both from kinetic and thermodynamic standpoint. The techniques used in these studies are steady-state and time-resolved fluorescence spectroscopy, differential scanning calorimetry, stopped-flow and temperature-jump relaxation spectroscopy.

Dr. Scott Kroeker

Research in our group involves the structural investigation of inorganic and organometallic materials. The principal method of characterization is nuclear magnetic resonance (NMR). As many of the materials of interest contain nuclei with quadrupole moments, substantial efforts are devoted to the development of NMR techniques designed to probe such systems.
Website: Kroeker Group

Dr. Joe O'Neil

Proteins carry out their biological functions through changes in conformation. We measure protein dynamics by NMR spectroscopy and hydrogen exchange chemistry to determine the timescale and magnitude of the conformational changes that explain the activities of a membrane protein, an HIV transcription activator and a viral enzyme.
Website: O'Neil Group

Dr. Jennifer van Wijngaarden

High resolution molecular spectroscopy and ab initio calculations are used to probe the lowest energy states of reactive species to gain better understanding of their structures and dynamics. The lab is equipped with custom-built, state-of-the-art microwave spectrometers and group members are also actively involved in infrared experiments at the Canadian Light Source synchrotron facility.
Website: van Wijngaarden Group