l-r, Mark Whitmore, Dean; Michael Butler, Distinguished Professor
and Joanne Keselman, Vice-President (Academic) and Provost
Michael Butler is a pioneer of research and development in the area of mammalian cell technology, an essential process for the production of biopharmaceuticals. He was one of the first people to recognize the need for a robust mammalian cell culture system and his research has been exceptionally successful in achieving this goal. He developed a novel perfusion system for the growth of anchorage-dependent mammalian cells, determined the biochemical requirements regulating cell growth, developed a defined culture media with additives for high yield, serum-free cell production, and defined conditions for controlling the glycosylation of recombinant proteins.
These breakthroughs have been adopted world wide for commercial use by biotechnology and pharmaceutical companies.
He has been an active teacher presenting courses in cell culture, industrial microbiology and membrane biochemistry, always receiving excellent reviews. He has authored or coauthored over 100 scientific articles including seven comprehensive books on mammalian cell technology, describing a spectrum of basic and applied work. His work has attracted over $4 million dollars in research funding to support the training of over 30 graduate students and postdoctoral fellows.
In addition to his research and teaching, he has contributed extensively to university administration and technical societies.