Joseph W. Gordon, PhD
Post-doctoral Fellow – Institute of Cardiovascular Sciences, St. Boniface Research Centre, Department of Physiology, Faculty of Medicine, University of Manitoba.
PhD - Department of Biology, York University, Toronto, Ontario. Supervisor: John McDermott PhD.
M.Sc. Department of Kinesiology and Health Science, York University, Toronto, Ontario. Supervisor: David Hood PhD.
Bachelor of Kinesiology. Department of Kinesiology, McMaster University, Hamilton, Ontario.
|Other Appointments (Academic/Research)|
Scientist, Manitoba Institute of Child Health, Winnipeg Manitoba.
Department of Human Anatomy and Cell Science, Faculty of Medicine, University of Manitoba.
Research Affiliate, Manitoba Centre for Nursing and Health Research, University of Manitoba.
Teaching Areas: Pharmacology, pathophysiology, anatomy, physiology, biochemistry, problem-based learning, web-based resources and open-source software in post-secondary education.
Transcriptional regulation of cardiovascular development and disease. Developmental regulation of insulin sensitivity in skeletal muscle.
Wang, E., Biala, A., Gordon, J.W., and Kirshenbaum, L.A. (2012). Autophagy in the Heart: Too much of a good thing? Journal of Cardiovascular Pharmacology. 60, 110-7.
Pagiatakis, C.*, Gordon, J.W.*, & McDermott, J.C. (2012). A novel RhoA-myocyte enhancer factor 2 dependent signalling pathway regulating vascular smooth muscle cell gene expression. Journal of Biological Chemistry. 287,8361-70. *Authors contributed equally to this work.
Gang, H., Hai, Y., Dhingra, R., Gordon, J.W., Aguilar, F., Yurkova, N., Aviv, Y., Leygue,E., & Kirshenbaum, L.A. (2010). A Novel Hypoxia-Inducible Splice Variant of Death Gene Bnip3 Promotes Survival of Ventricular Myocytes. Circulation Research 108, 1084-92.
Gang, H., Dhingra, R., Mughal, W., Gordon, J.W., & Kirshenbaum, L.A. (2011). Epigenetic Regulation of E2F-1 Dependent Bnip3 Transcription and Cell Death by NF-κB and HDAC1. Pediatric Cardiology 32, 263-6.
Gordon, J.W., Shaw, J.A., & Kirshenbaum, L.A. (2011). The multiple facets of NF-κB signaling pathways in the heart. Circulation Research 108, 1122-32.
Gordon, J.W., Pagiatakis, C., Du, M., Salma, N., Andreucci, J.J., Zhao, J., Perry, R.L.S., Hou, G., Bendeck, M., & McDermott, J.C. (2009). PKA regulated assembly of a MEF2/HDAC4 repressor complex controls c-Jun expression in vascular smooth muscle cells.Journal of Biological Chemistry 284, 19027-42.
Perry, R.L., Yang, C., Soora, N., Salma, J., Marback, M., Naghibi, L., Ilyas, H., Chan, J.,Gordon, J.W., & McDermott, J.C. (2009). Direct interaction between myocyte enhancer factor 2 (MEF2) and protein phosphatase 1alpha represses MEF2-dependent gene expression. Molecular and Cellular Biology 29, 3355-66.
Du, M., Perry, R., Salma, N., Gordon, J.W., Sui, M., & McDermott, J.C. (2008). Protein kinase A represses skeletal myogenesis by targeting myocyte enhancer factor 2D. Molecular and Cellular Biology 28, 2952-70.