Terms and conditions for downloading DRB typing trees:
Terms and conditions for downloading DRB typing trees: The DRB typing trees were made based on Taxonomy-based Sequence Analysis (TBSA) for HLA allele assignment in the heterozygous situations that occur in sequence-based HLA typing (1, 2). The DRB typing trees were created, partially, with the assistance of a computer program developed by Embedded Solutions Inc. (KBB, Winnipeg, Canada). These typing trees were developed based on the 1999 DRB database (3). These DRB trees can be used for manual DRB typing of both homozygous and heterozygous DNA samples.
These DRB trees can be used for Academic Research and study only, and can not be used for commercial purpose without permission of University of Manitoba. If you used the typing trees for your research please cite the reference 1 and 2 in your publication
- Luo M, Blanchard J, Pan Y, Brunham K, Brunham RC 1999 High-resolution sequence typing of HLA-DQA1 and -DQB1 exon 2 DNA with taxonomy-based sequence analysis (TBSA) allele assignment. Tissue-Antigens 54, 69-82
- Luo M, Blanchard J, Brunham K, Pan Y, Shen C.-X, Lu H, and Brunham RC Two-step, High Resolution Sequence-based HLA-DRB Typing of Exon 2 DNA with Taxonomy-based Sequence Analysis (TBSA) allele assignment (Submitted to Tissue Antigen)
- Robinson J, Malik A, Parham P, Bodmer JG, Marsh SG 2000 IMGT/HLA database--a sequence database for the human major histocompatibility complex. Tissue Antigens 55, 280-7
- Marsh SGE 1999 HLA class II region sequences, 1999, Anthony Nolan Research institute, (http://www.anthonynolan.com/HIG/data.html).