Dr. Alberto Severini
 

Assistant Professor, Medical Microbiology and Infectious Diseases.
Assistant Professor, Faculty of Pharmacy,
Chief, Viral Exanthemata and STD Section, National Microbiology Laboratory, Public Health Agency of Canada

Degrees: M.D., 1981 ( Parma , Italy ); Biochemistry and Clinical Chemistry, 1987
( Parma , Italy ).

Mailing Address:  Canadian Science Centre for Human and Animal Health 1015 Arlington Street, Winnipeg , MB , R3E 3R2

Tel: (204) 789-6022; Fax: (204) 789-2140; Lab: (204)789-6024
E-mail: Alberto.Severini@phac-aspc.gc.ca

 

Research Interests:
Human papillomavirus testing and molecular epidemiology. Molecular diagnostics. Genomics of herpesviruses. Herpesvirus replication and pathogenesis mechanisms.

Recent Publications:

  1. Berard AR, Cortens JP, Krokhin O, Wilkins JA, Severini A, Coombs KM. (2012) Quantification of the Host Response Proteome after Mammalian T1LReovirus Infection. PloS One. 7:e51939
  2. Demers AA, Shearer B, Severini A, Lotocki R, Kliewer EV, Stopera S, Wong T, Jayaraman G. (2012) Distribution of human papillomavirus types, cervical cancer screening history, and risk factors for infection in Manitoba. Chronic Dis Inj Can. 32:177-185.
  3. Fan Q, Amen M, Harden M, Severini A, Griffiths  A , and Longnecker R (2012) Herpes B virus and Cercopithecine herpesvirus 2 utilize human nectin-1 for entry, but not HVEM.  J Virol 86:4468-4476
  4. Zubach V, Smart G, Ratnam S and Severini A (2012) A Novel Microsphere-Based Method for the Detection and Typing of 46 Mucosal Human Papillomavirus Types, J Clin Microbiol. 50:460-464.
  5. Jiang Y, Brassard P, Severini A, V Goleski , Santos, Leamon A, Chatwood S, Lys C,  Johnson G, Wong T, Kotaska A,  Kandola K, Mao Y (2011) Type-Specific Prevalence of Human Papillomavirus Infection among Women in the Northwest Territories, Canada. Journal of Infection and Public Health 4:219-27.
  6. Tohme S, Cukier C and Severini  A (2011) RNA binding properties of the US11 protein from five primate simplexviruses. Virology J 8:504
  7. Jiang Y, Brassard P, Severini A, Goleski V, Santos M, Leamon A, Chatwood S, Lys C, Johnson G, Wong T, Kotaska A, Kandola K, Mao Y. Type-specific prevalenc of Human Papillomavirus infection among women in the Northwest Territories, Canada. J Infect Public Health. 2011 (5-6):219-27
  8. Gilbert M, Kwag M, Mei W, Rank C, Kropp R, Severini A, van Niekerk D, Zhou C, Press N, Ogilvie G, Wong T; the ManCount Study Team (2011) Feasibility of Incorporating Self-Collected Rectal Swabs Into a Community Venue-Based Survey to Measure the Prevalence of HPV Infection in Men Who Have Sex With Men. Sex Transm Dis. 38:964-969.
  9. Norberg P, Tyler S, Severini A, Whitley R,  Liljeqvist J and Bergstrom T (2011) A complete genome based comparative evolutionary analysis of herpes simplex virus type 1 and varicella zoster virus. PloS One. 6:e22527.
  10. Schellenberg JJ,  Links MG, Hill JE,  Dumonceaux TJ,  Kimani J, Jaoko W, Wachihi C,  Mungai JN, Peters GA, Tyler T, Graham M, Severini A, Fowke KR, Ball TB, Plummer FA (2011) Molecular definition of vaginal microbiota in East African commercial sex workers. Appl Environ Microbiol 77:4066-74
  11. Andall-Brereton GM, Salas RA, Hosein F, Mohammed W, Monteil MA, Goleski V, Severini A, Carrington C, Quesnel SMM, Boodram LL, Boisson E, Laquis G, Akpaka PE,  Paul RC (2011) Human Papilloma Virus Prevalence in a sample of Women in the Caribbean island of Trinidad.  Rev Panam Salud Publica 29:2220-2226.
  12. Zehbe I, Moeller H, Severini A, Weaver B, Escott N, Bell C, Crawford S, Bannon D, Paavola N. (2011). Feasibility of self-sampling and human papillomavirus testing for cervical cancer screening in First Nation women from Northwest Ontario, Canada: a pilot study BMJ Open 2011;bmjopen-2010-000030
  13. Tyler S, Severini A, Black D, Walker M and  Eberle R (2011) The Genome Sequence and Structure of Saimirine herpesvirus 1. Virology. 410:181-191.
  14. Zahariadis G, and  Severini A (2010) Evaluation of a novel serology algorithm to detect Herpes Simplex Virus 1 or 2 antibodies. Sex Transm. Dis. 37:696-699.
  15. DeCarlo CA, Severini A, Edler L, Escott NG, Ulanova M, Zehbe I (2010) IFN-κ, a novel type I IFN, is undetectable in HPV-positive human cervical keratinocytes. Laboratory Investigation 90:1482-1491.
  16. Kliewer EV, Demers AA, Brisson M, Severini A, Lotocki R, Elias B, Hammond G, Wurtak G , the Manitoba HPV Research Group (2010) The Manitoba Human Papillomavirus Vaccine Surveillance  and Evaluation System. Statistics Canada Health Reports. 21:1-7.   

Laboratory Members:

Jennifer Beirnes Technician On leave
 
Dana Cabiles Grad Student dana.cabiles@phac-aspc.gc.ca
789-6085
Suzanne Gibbons Biologist suzanne.boudreau@phac-aspc.gc.ca
789-6024
Vanessa Zubach Technician vanessa.zubach@phac-aspc.gc.ca
789-6024
Joanne Hiebert Biologist joanne.hiebert@phac-aspc.gc.ca 
789-7055
Dr. Elizabeth McLachlan Biologist elizabeth.mclachlan@phac-aspc.gc.ca
789-7042
Lillian Mendoza Technician lillan.mendoza@phac-aspc.gc.ca
789-6085
Anne Peterson Technician anne.peterson@phac-aspc.gc.a
789-5055
Felicia Preston Technician felicia.preston@phac-aspc.gc.ca
789-6024
Helene Schulz Grad Student helene.schulz@phac-aspc.gc.ca
789-6024
Sarah Tohme Technician sarah.tohme@phac-aspc.gc.ca
789-6085