Distinguished Visiting Professors and Guest Speakers
in the Department of Immunology
1998-2004

Alec Sehon Distinguished Professorship in Allergy
Samuel Weiner Distinguished Visitor Viventia Biotech, Inc. Distinguished Professor of Immunology



The Alec Sehon Distinguished Professorship in Allergy
Dr. Mark Larché
Reader in Respiratory Immunology
National Asthma Campaign Senior Research Fellow
Imperial College, London
Faculty of Medicine
National Heart and Lung Institute
London, England

Switching immunity on and off in vivo: studies with T cell epitopes

May 25, 2004

Sponsored by Merck Frosst Canada & the Manitoba Medical College Foundation
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Dr. Donata Vercelli
Arizona Respiratory Center, Tucson, Arizona

Genetics of IL-13 and functional relevance of IL-13 variants in pathogenesis of immediate hypersensitivity diseases
May 23, 2003

Sponsored by Merck Frosst Canada
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Dr. Frederica Sallusto
Institute for Research in Biomedicine
Bellinzona, Switzerland

The role of chemokine receptors in orchestrating primary,
effector and memory immune responses

October 29, 2001

Dr. Federica Sallusto
Dr. Sallusto is well known for her recent ground-breaking discoveries published in Science, Nature, and the Journal of Experimental Medicine on how immune responses are initiated and controlled.

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Dr. Stephen Holgate
Divisional Director, Respiratory, Cell & Molecular Biology
Research Division
MRC Clinical Professor of Immunopharmacology
University of Southampton School of Medicine

Asthma: A disease more than airway inflammation
September 11, 2000

(Supported in part by Merck Frosst Canada & The Manitoba Medical College Foundation)

and

Novel therapeutic approaches to treating asthma
September 13, 2000

(Jointly sponsored by the Section of Respirology and the Department of Immunology)
Dr. Stephen Holgate
For more information Dr. Holgate's research interests and recent publications, please his web page on the University of Southampton School of Medicine web site.
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Samuel Weiner Distinguished Visitor
Dr. Adrian Hayday
Kay Glendinning Professor
Guy's King's St. Thomas' Medical School
University of London, United Kingdom

Exploring the third way of protection in immunology
January 30, 2001

and

Assessing a thymocyte's competence for further development

January 31, 2001

(Jointly sponsored by the Office of Research Services
with the Departments of Immunology, Pediatrics, Medical Microbiology,
Internal Medicine and Pathology)

Dr. Adrian Hayday
The multiple cell types and functions in such interactions are increasingly seen as the key to understanding how antigens delivered to body surfaces elicit either immunity, tolerance or autoimmunity. In the first lecture Dr. Hayday presented an overview of recent exciting discoveries in our quest to determine how the mucosal immune system protects you.

The second lecture represented recent and unpublished data on the role of signaling in T cell ontogeny.

Recent work from this laboratory (Immunity (2000) 13: 677-689; EMBO J (2000) 19: 3337-3348) examines the role of key transcription factors such as NF-KB and pre-T cell receptor expression in T Cell development.

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The Annual Viventia Biotech, Inc.
Distinguished Professor of Immunology Lecture
Dr. Ralph Steinman
Professor and Senior Physician
Cellular Physiology and Immunology
The Rockefeller University
New York, New York

Dendritic cells: Sentinels for antigen-specific tolerance and immunity
March 30, 2004
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Dr. Paul Kubes
Chair, Immunology Research Group
Department of Physiology and Biophysics
University of Calgary

The physiology of how white cells leave the vasculature - from cells to mice to humans
May 14, 2002

and

Multiple overlapping and overriding pathways are required for effective neutrophil recruitment to sites of inflammation
May 15, 2002
Dr. Paul Kubes
For more information on Dr. Kubes's work, please see his list of recent publications and his page on the University of Calgary website.
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Dr. Marc Jenkins
Professor, Department of Microbiology, Center for Immunology
University of Minnesota

In vivo analysis of the activation of antigen-specific CD4 T and B cells
December 9, 1999

and

Visualizing an antigen-specific immune response in the body
December 10, 1999
For information on Dr. Jenkin's research and a list of his recent publications, please see his web page at the University of Minnesota.
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Dr. Robert Lechler
Imperial College School of Medicine at Hammersmith Hospital
London, England

Cognate and non-cognate mechanisms of immunoregulation
September 28, 1998

and

Beyond hyperacute rejection:
Overcoming the obstacles to successful xenotransplantation

September 29, 1998
For more information on Dr. Lechler's work, please see his list of recent publications and his page on the Hammersmith Hospitals NHS Research Website.
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Guest Speakers 2004
Dr. Hamida Hammad
Department of Immunology
Erasmus University Rotterdam
The Netherlands

Taking our breath away: Dendritic cells in the pathogenesis of asthma
July 27, 2004
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Dr. Jody Berry
National Centre for Foreign Animal Disease/
Canadian Food Inspection Agency
Supervisor, National Microbiology Laboratory
Monoclonal Antibody Section
Government of Canada

From the SARS virus to Anthrax toxins:
How can we slay these monsters by exploiting host antibody responses?
June 10, 2004

Dr. Jody Berry's web page at the University of Manitoba

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Dr. Mark Larché
Reader in Respiratory Immunology
National Asthma Campaign Senior Research Fellow
Imperial College, London
Faculty of Medicine
National Heart and Lung Institute
London, England

Peptide-based vaccines for allergy and autoimmunity
May 25, 2004
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Dr. Heyu Ni
Laboratory Medicine and Pathobiology
University of Toronto

Novel mouse model of alloimmune thrombocytopenia:
Maternal immune response to featal 3 βintegrin
May 6, 2004
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Dr. Wendy Ungar
Health Policy, Management and Evaluation
University of Toronto
Research Institute Scientist
Population Health Sciences
The Hospital for Sick Chidren, Toronto

The impact of economic barriers on health outcomes in children with asthma
April 29, 2004
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Dr. Ruey-Chyi Su
Post Doctoral Fellow
Howard Hughes Medical Institute
UCLA School of Medicine

Assembly of silent chromatin during thymocyte development
April 1, 2004
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Dr. Ralph Steinman
The Rockefeller University
New York, New York

Dendritic cell maturation: A control point for peripheral tolerance and immunity

March 30, 2004
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Dr. Kamala D. Patel
Associate Professor
Department of Physiology and Biophysics and
Biochemistry and Molecular Biology (joint)
Faculty of Medicine
University of Calgary

Mechanisms of eosinophil adhesion and activation

February 12, 2004

Co-sponsored by
the National Training Program in Allergy and Asthma
and the Manitoba Institute of Child Health


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Dr. Ed Palmer
Laboratory of Transplantation Immunology & Nephrology
University Hospital
Basel, Switzerland

The T cell receptor: A molecular complex that can make a T cell laugh or cry
February 9, 2004
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Guest Speakers 2003
Dr. Michael Julius
Vice President, Research
Sunnybrook and Women's College
Health Sciences Centre
and
Professor, Departments of Immunology & Medical Biophysics
Faculty of Medicine
University of Toronto

Subcellular Compartmentalization of Src Family Tyrosine Kinases and the Regulation of T Cell Antigen Receptor Signalling
December 11, 2003

Dr. Michael Julius's web page at the University of Toronto
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Dr. Manel Jordana
Professor, Department of Pathology & Molecular Medicine
Head, Division of Respiratory Diseases and
Allergy Centre for Gene Therapeutics
McMaster University

Asthma Modeling: Intimation Through Imitation
December 3, 2003

Dr. Jordana's web page at McMaster University
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Dr. Blanca Camoretti-Mercado
University of Chicago

Gene Regulation in the Lung: Novel roles of resident cells, inflammatory mediators and transcription factors in health and disease
November 27, 2003
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Dr. Michael Gold
Associate Professor
Department of Microbiology and Immunology
University of British Columbia

The role of the Rap GTPases in B cell antigen receptor and chemokine receptor signaling
November 20, 2003

Co-sponsored by the Department of Immunology and the Faculty of Medicine's Molecular Biology Seminar Series

Dr. Michael Gold's web page at the University of British Columbia
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Dr. Stephen I. Rennard, MD
University of Nebraska Medical Center, Omaha Pulmonary and Critical Care Medicine

COPD: New Understanding, New Options

and

The American Hypothesis: COPD as a Disease of Repair
November 18, 2003

Sponsored by GlaxoSmithKline
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Dr. Giovanni Piedimonte, M.D.
Department of Pediatrics
Batchelor Children's Research Institute
University of Miami School of Medicine

Virus-Induced Airway Remodeling: A New Hypothesis for the Origins of Asthma in Early Life
October 23, 2003

Presented in conjunction with Pediatric Research Rounds Generously sponsored by Merck Frosst
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Dr. Tak Mak
Department of Medical Biophysics
University of Toronto & Ontario Cancer Institute

'Tis Death That Makes Life Live
October 22, 2003


Dr. Tak Mak's web page at the University of Toronto
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Dr. Denis Kinane
University of Louisville, School of Dentistry
Delta Dental Endowed Professor & Associate Dean for Research and Enterprise

Immune and inflammatory responses to periodontal disease
October 1, 2003
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Dr. Megan Levings
San Raffaele Telethon Institute for Gene Therapy, Milan, Italy
and University of British Columbia, Vancouver

The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells: A role in the Hygiene Hypothesis?
May 23, 2003
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Dr. Tom Platts-Mills
Asthma and Allergic Disease Center, University of Virginia

The immune response to intrinsic and extrinsic allergens in early life:
determinants of allergic disease?

May 23, 2003
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Dr. Roger Lauener
Zurich University Children's Hospital, Switzerland

Farmers' children, allergies and innate immunity
May 22, 2003
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Dr. Parameswaran Nair
Canadian Institutes of Health Research Fellow
Firestone Institute for Respiratory Health
St. Joseph's Healthcare & McMaster University

Modulation of airway smooth muscle function by cysteinyl leukotrienes
May 8, 2003

Presented in combination with Pediatric Research Rounds Co-sponsored by the National Training Program in Allergy and Asthma Generously sponsored by Merck Frosst

and

Novel aspects of leukotriene biology in asthma
May 7, 2003

Presented in combination with Respiratory Research in Progress. Co-sponsored by the National Training Program in Allergy and Asthma Generously sponsored by Merck Frosst
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Dr. Ed Clark
Departments of Microbiology and Immunology
University of Washington
Seattle, Washington

Regulation of B cell proliferation and cell fate
May 2, 2003

Co-sponsored by the Department of Immunology and the Molecular Biology visiting speaker program
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Dr. Yassine Amrani
Pulmonary, Allergy and Critical Care Division
University of Pennsylvania

G Protein Coupled Receptors: Multifaceted Therapeutic Targets for Chronic Lung Diseases
April 23, 2003

Presented by the Asthma/COPD Research Centre and the National Training Program in Allergy and Asthma, and generously sponsored by Merck Frosst

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Dr. Lisa Cameron
Functional Genomics Laboratory
Arizona Respiratory Center
University of Arizona

Altered IL-13 Promoter Activity by the Single Nucleotide Polymorphism (SNP) - 112C/T
April 17, 2003
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Dr. Jude Uzonna
Research Associate
Department of Clinical Studies
School of Veterinary Medicine
University of Pennsylvania

Immunity to Leishmania major: paradigm drifts and/or shifts?
April 10, 2003

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Dr. Konstantin Salojin
Diabetogen Biosciences Inc., & Autoimmunity/Diabetes Group
The John P. Robarts Research Institute
London, Ontario

Altered T-Cell receptor signaling: effects on autoimmune disease
March 20, 2003
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Dr. Sam Kam-Pun Kung
Departments of Microbiology and Immunology and Medicine
David Geffen School of Medicine at U.C.L.A.

To Tame a Killer: Turning HIV-1 into a therapeutic vector for immunologists
March 13, 2003
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Guest Speakers 2002
Dr. Qutayba Hamid
James McGill Professor
Departments of Medicine and Pathology
McGill University

The Development of Asthma
December 11, 2002

and

Eosinophils in Allergic Diseases
December 12, 2002
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Dr. Jilly Evans
Visiting Scientist, Merck Frosst

Cysteinyl Leukotriene Receptors: Targets in inflammatory diseases
October 28, 2002
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Dr. Malcolm Sears
Director, Firestone Regional Chest & Allergy Unit, St. Joseph's Hospital
Head, Respirology, Department of Medicine, McMaster University
Hamilton, Ontario

Epidemiology of Asthma
October 17, 2002
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Dr. David Proud
Canada Research Chair in Inflammatory Airway Diseases
Professor, Department of Physiology & Biophysics,
Respiratory Research Group
University of Calgary

Viral exacerbation of airway inflammation
October 10, 2002

Co-sponsored by the CIHR National Training Program in Allergy and Asthma and the Department of Immunology
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Dr. Yassine Amrani
Pulmonary and Critical Care Division
Department of Medicine
University of Pennsylvania Medical Center

Airway smooth muscle: contraction and beyond
Oct 10, 2002

Co-sponsored by the Section of Respiratory Disease

and

Interferons and airway smooth muscle in the pathogenesis of asthma
Oct 10, 2002

Co-sponsored by the CIHR National Training Program in Allergy and Asthma and the Department of Immunology
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Dr. Paul O'Byrne
Director, Firestone Institute for Respiratory Health
McMaster University
Hamilton Ontario

The Evolution of Asthma Management
September 28, 2002

Sponsored by AstraZeneca
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Dr. Sidong Xiong
Department of Immunology
Fudan University
The Center for Gene Immunization and Vaccine Research (Shanghai)

Molecular Designing of New Vaccine
August 29, 2002

Sponsered by the Manitoba Institute of Child Health,
the Department of Immunology and the Department of Medical Microbiology
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Guest Speakers 2001
Dr. Kevin Kane
Department of Medical Microbiology and Immunology
University of Alberta

Regulation of natural killer cell function by Ly-49 receptors
November 23, 2001
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Dr. Abdelilah Soussi Gounni
Meakins Christie Labs
McGill University

A potential role of interleukin-9 in the pathogenesis of asthma
March 1, 2001

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Dr. Subburaj Ilangumaran
Department of Experimental Therapeutics
Ontario Cancer Institute, Princess Margaret Hospital
and University of Toronto

Role of SOCS1 in signaling protein homeostasis in mast cells
February 15, 2001
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Dr. Michiko Kobayashi
Senior Scientist, Pulmonary Diseases
Genetics Institute
Cambridge, Massachusetts

The role of IL-13 in allergic asthma
February 9, 2001
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Dr. Gillian Stephens
Department of Clinical Pharmacology
Royal College of Surgeons in Ireland

The role of the conserved KVGFFKR sequence
in the functional regulation of TH platelet specific integrin,
alpha IIb beta 3

January 26, 2001
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Guest Speakers 2000
Dr. Grant Gallagher
University of Glasgow
Department of Surgery
Glasgow Royal Infirmary
Glasgow, Scotland

Role of cytokine genes
December 13, 2000
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Dr. Persephone Borrow
The Edward Jenner Institute for Vaccine Research
Berkshire, United Kingdom

Why does the early immune response not mediate
better control of HIV-1 infection?


August 15, 2000
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Dr. David Tough
The Edward Jenner Institute for Vaccine Research
Berkshire, United Kingdom

Immune stimulation by type 1 IFN

August 14, 2000
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Dr. Toshifumi Mikayama
Vice President, Chief Scientific Officer
Gemini Science, Inc. Research Laboratory
San Diego, California

Expression of fully human antibodies in trans-chromosomic mice
June 14, 2000
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Dr. Judah Denburg, M.D., FRCP(C)
Professor of Medicine and
Director, Division of Allergy & Immunology
Faculty of Health Sciences, McMaster University

Allergy Through the Looking Glass:
A Bone Marrow Disorder?

April 13, 2000

and

Regulation of Inflammatory Cell Differentiation
in allergic inflammation

April 13, 2000

(Jointly presented by the Department of Immunology
and the Department of Pediatrics and Child Health)
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Dr. Barbara Fazekas de St. Groth
NHMRC Principal Research Fellow
Head, T Cell Biology Group
Centenary Institute of Cancer Medicine and Cell Biology
Sydney, Australia

Regulatory mechanisms of peripheral T cell tolerance
April 7, 2000

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Dr. Pere Santamaria
Department of Microbiology and Infectious Diseases
University of Calgary

Antigenic specificity, repertoire and role of CD8+ cells
in spontaneous autoimmune diabetes


March 16, 2000
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Dr. Graham Tipples
Head, Viral Exanthemata Laboratory
Canadian Science Centre for Human and Animal Health
Laboratory Centre for Disease Control

Molecular epidemiology of measles virus
March 2, 2000
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Guest Speakers 1999
Dr. Peter Bretscher
Department of Microbiology
College of Medicine
University of Saskatchewan

Coherence and independence of immune responses
November 3, 1999
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Dr. Abul Ekramoddoullah
Senior Research Scientist
Tree Biotechnology and Advanced Genetics
Canadian Forest Service, Pacific Forestry Centre
Victoria, B.C.

Proteomic approaches to the analysis of plant defense responses:
Strategies to genetically engineer single chain antibodies


August 18, 1999
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Dr. Rachel McKenna
Department of Pathology and Laboratory Medicine
Faculty of Medicine
University of Calgary

The role of anti-HLA antibodies in organ rejection
January 18, 1999
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Guest Speakers 1998
Dr. Wayne Lapp
Department of Physiology
McGill University

Acute Graft-vs.-Host disease
Nov. 6, 1998
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Dr. Redwan Moqbel
Professor of Medicine and Deputy Director
Astra Asthma Research Group
University of Alberta

Regulation of pro-inflammatory release from activated eosinophils in asthma
October 26, 1998
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Dr. Alan Young
Basel Institute for Immunology
Basel, Switzerland

Developmental and subset-specific regulation of lymphocyte traffic in vivo

October 21, 1998
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Dr. Mary Perdue
Director, Intestinal Disease Research Program
and Professor, Department of Pathology
McMaster University

Gut feelings: The interaction of psychological, neural and immune factors
in the regulation of intestinal function


June 25, 1998
(Jointly sponsored with the Section of Gastoenterology, Department of Internal Medicine)
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Dr. Linda Pilarski
Cross Cancer Institute
University of Alberta

Multiple myeloma: The malignant clone is a hierarchy of
sequentially related B lineage cells
that share IgH VDJ gene rearrangements


June 26, 1998
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Dr. Will Taylor
Department of Pharmaceutical & Biomedical Sciences &
Computational Centre for Molecular Structure and Design
The University of Georgia

The role of vitally encoded selenoprotein modules
in HIV-1 pathogenesis


April 28, 1998
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