Untitled Document

Local Principal Investigator, 1994-1999. Comparison of raloxifene Hcl and placebo in the treatment of postmenopausal women with osteoporosis. Coordinated/supported by El Lilly and Company. Results published: Cummings SR, Eckert S, Krueger KA, et al. The effect of raloxifene on risk of breast cancer in postmenopausal women. Journal of the American Medial Association 1999;281:2189-2197 and Ettinger B, Black DM, Mitlak BH, et al. Reduction of vertebral fracture risk in psotmenopausal women with osteoporosis treated with raloxifene. Journal of the American Medial Association 1999;282:637-645.

Local Co-Principal Investigator, 1996-present. A randomized trial of the effect of low-molecular-weight heparin versus warfarin sodium on mortality in the long-term treatment of proximal-vein thrombosis (LITE). Coordinated by Clinical Trials Unit of Calgary, Canada. Supported by Leo Pharmaceutical Products Ltd of Denmark.

Local Principal Investigator, 1996-1998. A protocol for the use of Oncoscint CR/OV-In111 as a diagnostic agent for patients with known colorectal adenoarcinomas. Coordinated/supported by Faulding Canada Ltd.

External supervisor for Randy Fransoo; M.Sc. thesis preparation (1991-1994), M.Sc. awarded 1994. "Skeletal status following spinal cord injury".

Supervisor for Mr. Andrew Borys; B.Sc. (Med) project (1992-1993). "Comparison of methods for head tilt correction in brain SPECT".

Supervisor for Mr. Jon Havelock, B.Sc. (Med) project (1995-1996). "Radiation doses recevied by contacts to patients treated with iodine-131 for hyperthyroidism". Selected to represent Univeristy of Manitoba at the Midwest Student Research Forum.

Supervisor for Dr. M Pimentel and Dr. R. Mathur, Resident Project (1995-present). "An analysis of the contribution of ventilation assessment in the scintigraphic diagnosis of pulmonary embolism and implications for cost-effective strategies".

Supervisor for Dr. J. Choy, Resident Project (1995-present). "Lung uptake of [Tc-99m]sestamibi in relation to angiographic severity and extent of coronary artery disease."

External supervisor for Scott King, PhD (1996-present). "In vivo MR spectroscopy for tissue characterization of thyroid nodules".

External Supervisor for Qing Chen; M.Sc. (1998-present). "Co_registration of nuclear medicine (SPECT and PET) and conventional (CT and MRI) imaging."

External Supervisor for Kathy Green; M.Sc. (1999-present). "Effects of diabetes and polyunsaturated fatty acid supplementation on bone metabolism."

Clinical Resource Management Task Force, Member 1993-1994
Search Committee for Section Head of Nuclear Medicine, Member, 1993
Working Group on Acute Myocardial Infarction, Member, 1993-1994
Department of Medicine Executive Committee, Member, 1994-1998
Department of Medicine Computer Committee, Member, 1994-1997
Medical Advisory Committee, Member, 1995-1998
Executive Management Committee, Medical Advisory Council, Member, 1995-1998
Joint Administration/Medical Staff Executive Committee, Member, 1995-1998
Joint Committee of the SBGH and HSC Executive Officers, Member, 1995-1997
Information Services Steering Committee, Member, 1995-1997
Department of Medicine Service Chiefs Committee, Member, 1996-1997
Department of Medicine Clinical Team Managers Committee, Member, 1997-1998
Department of Medicine Program Committee, Member, 1997-1998

Nuclear Medicine Training Committee, Member, 1990-present
Faculty Committee of Examiners III, Member, 1991-1993
Faculty Clerkship Committee, Member, 1991-1998
Faculty Clerkship Clinical Examination Committee, Member, 1992-1993
Internal Medicine Subcommittee for the Clerkship Clinical Examination, Chair, 1992-1994
Search Committee for Section Head of Endocrinology and Metabolism, Member, 1993-1996
Faculty Library Committee, Member, 1994-1997
Faculty Executive Council, Faculty of Medicine, Member, 1995-1999
Nuclear Medicine Research Committee, Co-Chair, 1995-present
Endocrinology Systems Block Curriculum Committee, Radiology Representative, 1996-present
Faculty Communication Skills Committee, Member, 1996-1998
Clinical Investigator Program Training Committee, Member, 1996-1998
Ad Hoc Clerkship Overlap and Link Subcommittee, Member, 1996-1997
Ad Hoc Clerkship and Link Review Subcommittee, Member, 1997-1999

Provincial Nuclear Medicine Advisory Task Force, Member, 1991-1995
Provincial Nuclear Medicine Advisory Task Force, Chair, 1996-present
Provincial Imaging Advisory Committee, Member, 1996-present
Health Professional Committee, Manitoba Chapter of the Canadian Osteoporosis Society, Member, 1997-present
Manitoba Bone Density Program Committee, Chair, 1997-present
Organizing Committee Advisory, Rehabilitation Challenges for the New Millenium, Winnipeg, 1999

Organizing Committee, 29th Annual Meeting of the Society of Nuclear Medicine Prairie Provinces Chapter, Winnipeg, 1997
Organizing Committee, Manitoba Saskatchewan Osteoporosis Interest Group, 1997.
Scientific Advisory Board, Osteoporosis Society of Canada, Member, 1997-present
Canadian Society of Nuclear Medicine, Radiopharmaceuticals Committee, CANM Representative, 1991-present
Canadian Society of Nuclear Medicine, Board of Directors and Radiopharmaceuticals Committee, Chair, 1991-present
Scientific Advisory Board, Osteoporosis Society of Canada, Executive Board, 1999-present
Guidelines Diagnosis Committee, Osteoporosis Society of Canada, Member, 2000-present
Guidelines Implementation Committee, Osteoporosis Society of Canada, Member, 2001-present

LESLIE WD, Roe B. Osteoporosis and bone densitometry. In:Handbook of Nuclear Medicine. Landes Bioscience: Georgetown TX, 2003.

LESLIE WD, Plourde P. Inflammatory disorders. In: Handbook of Nuclear Medicine Landes Bioscience: Georgetown TX, 2003

LESLIE WD, Greenberg ID (eds). Handbook of Nuclear Medicine. Landes Bioscience: Georgetown, TX, 2003.

Gall RM, Witterick IJ, Noyek A, LESLIE WD. Preoperative localization tests. In: Surgery of the Thyroid and Parathyroid Glands. Saunders: Philadelphia, PN, 2003.

LESLIE WD, Metge CJ, Salamon EA, Yuen CK, Wood Steiman P. The determination of the burden of osteoporosis in the Canadian aboriginal population. In: Aboriginal Health, Identity, and Resources. Oakes J, Riewe R, Koolage S, Simpson L, Shuster N eds. Native Studies Press: Winnipeg, Canada, 2000.

LESLIE WD. Nuclear imaging in inflammatory disease. Medicine North America May/June 1997:43-48.

LESLIE, W.D. Determination of the reference range: The problem of small sample sizes. Presented at the Fifth World Congress of Nuclear Medicine and Biology, Montreal, 1990. Published in The European Journal of Nuclear Medicine 16:S200, 1990.

Ward L, LESLIE WD, McLellan Y. Practical guidelines for flood uniformity in SPECT. Presented at the Conjoint Meeting of the Canadian Association of Nuclear Medicine and the Prairie Provinces Chapter, Society of Nuclear Medicine, Banff, 1991. Published in Clinical Nuclear Medicine 1991.

LESLIE WD, Nance P. Dissociated hip and spine demineralization from spinal cord injury. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Winnipeg, 1992 and The NCE Network for Neural Regeneration and Recovery, Toronto, 1992. Published in The Proceedings of the NCE Network for Neural Regeneration and Recovery.

LESLIE WD. Variability in whole body effective dose equivalent weighting factors: A Monte Carlo study. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Winnipeg, 1992 and at the Joint Meeting of the 61st Annual Meeting of the Royal College of Physicians and Surgeons of Canada and the Canadian Association of Nuclear Medicine, Ottawa, 1992. Published in Clinical and Investigative Medicine Supplement to 15(4):A104, 1992.

Maclean JP, LESLIE WD. Estrogen and bone density: A comparison of tamoxifen and hypoestrogenemia. Presented at the Annual Meeting of the Society of Nuclear, Toronto, 1993. Published in The Journal of Nuclear Medicine 34(5):165P, 1993.

LESLIE WD. Motion detection and correction routines: Preliminary experience with NPATMOT. Presented at the Apex Users' Meeting linked to the Annual Meeting of the Society of Nuclear Medicine, Toronto, 1993. Published in Apex Spectator 5(1):30-31, 1993.

Pearson E, Nance PW, LESLIE WD, Ludwig S. Severe adverse effects following the use of calcitonin to prevent osteoporosis in acute spinal cord injury. Presented at the 62nd Annual Meeting of the Royal College of Physicians and Surgeons of Canada Vancouver, 1993. Published in Clinical and Investigative Medicine Supplement to 16(4):B112, 1993.

LESLIE WD, Abrams D, Greenberg CR, Hobson D, McDonald D. Direct comparison of [I-123] epidepride and [I-123] IBZM for dopamine D2 receptor imaging. Presented at the Society of Nuclear Medicine Meeting, Minneapolis, 1995. Published in The Journal of Nuclear Medicine 1995; 36(5):255P.

LESLIE WD, Dupont JO, McDonald D, Peterdy AE. Comparison of motion correction algorithms for cardiac SPECT. Presented at the Society of Nuclear Medicine Meeting, Minneapolis, 1995. Published in The Journal of Nuclear Medicine 1995; 36(5):59P.

Salamon E, LESLIE WD, Metge CJ, Dale J, Yuen CK. Increased incidence of hip fractures in American Indians living in northern latitudes. Presented at the American Society of Bone Metabolism Research, Cincinnati, 1997. Published in The Journal of Bone and Mineral Research August 1997; 12(1):S139.

LESLIE WD, DeVos G, Peterdy AE, Dupont JO. Precision of bone mineral apparent density measurement. Presented at the 22nd Annual Meeting of the American Society for Bone Metabolism Research, Toronto, 2000. Abstract published in Journal of Bone Mineral Metabolism 2000; 15 (Suppl 1):S285.

LESLIE WD, Metge C, Yuen CK, Kvern B, Anderson W, Trasler T. Maximizing osteoporosis management in Manitoba (MOMM) - The rationale and methods of a large optimal care program. Presented at the 22nd Annual Meeting of the American Society for Bone Metabolism Research, Toronto, 2000. Abstract published in Journal of Bone Mineral Metabolism 2000; 15 (Suppl 1):S560.

LESLIE WD, Metge C, Caetano P. Have clinical risk factors been underutilized for fracture prediction? Presented at the 22nd Annual Meeting of the American Society for Bone Metabolism Research, Toronto, 2000. Abstract published in Journal of Bone Mineral Metabolism 2000; 15 (Suppl 1):S541.

LESLIE WD, Metge C, Caetano P. A holistic approach to hip fracture risk stratification. Presented at the 22nd Annual Meeting of the American Society for Bone Metabolism Research, Toronto, 2000. Abstract published in Journal of Bone Mineral Metabolism 2000; 15 (Suppl 1):S416.

LESLIE WD, Metge C, Ward L. Contribution of age and clinical risk factors to DEXA-based hip fracture risk stratification using a multidimensional model. Presented at the 23rd Annual Meeting of the Americal Society for Bone Metabolism Research, Phoenix, 2001. Abstract published in Journal of Bone and Mineral Research 16 (Suppl 1):S398, 2001.

LESLIE WD, Metge C, Kvern B, Anderson W, Manness LJ, Yuen K. Population-based prevalence of clinical risk factors from the Maximizing Osteoporosis Management in Manitoba (MOMM) Project. Presented at the 23rd Annual Meeting of the American Society for Bone Metabolism Research, Phoenix, 2001. Abstract published in Journal of Bone and Mineral Research 16 (Suppl 1):S520, 2001.

Metge C, LESLIE WD, Kvern B, Anderson WA, Manness LJ, Yuen K. Population-based prevalence of medical risk factors for osteoporosis from the Maximizing Osteoporosis Management in Manitoba (MOMM) Project. Presented at the 23rd Annual Meeting of the American Society for Bone Metabolism Research, Phoenix, 2001. Abstract published in Journal of Bone and Mineral Research 16 (Suppl 1):S520, 2001.

Caetano P, Metge C, LESLIE WD. Population-based analysis of osteoporosis treatment and prevention using a combination of administrative databases, a clinical bone mineral density database and survey data. Presented at the meeting of the International Osteoporosis Foundation, Lisbon, 2002. Abstract published in Osteoporosis International 13 (Suppl 1):S86, 2002.

Taback SB, LESLIE WD, Van Vliet G, Guyda HL, Tenenhouse A. The effect of growth hormone on young adult bone density in Turner syndrome. Presented at the 2nd International Conference on Children's Bone Health, Sheffield, 2002. Abstract published in Calcified Tissue International 2002.

Metge CJ, Yuen CK, LESLIE WD, Yogendran M, Kvern B, Manness LJ. Using a population-based evidence-based disease management program to prevent and treat osteoporosis in postmenopausal women. Presented at the 24th Annual Meeting of the American Society for Bone Metabolism Research, San Antonio, 2002. Abstract published in Journal of Bone and Mineral Research 17 (Suppl 1):S360, 2002.

LESLIE WD. Elution characteristics of technetium-99m labeled erythrocytes in relation to scintigraphic detection of gastrointestinal bleeding. Presented at the Meeting of the Canadian Association of Radiologists, Quebec City, 1989.

LESLIE WD. Motion correction in SPECT: An integrated approach. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Winnipeg, 1992.

LESLIE WD, Palser R. Propagation of error calculations: calculus versus coin toss. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Saskatoon, 1993.

LESLIE WD, Shojania AM, Abrams DN, McDonald DM. Low serum vitamin B12 and normal Schilling test: what is the next step? Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Saskatoon, 1993.

Levin D, LESLIE WD, Stern S, Billinghurst MW. Requiem for 99mTc-pyrophosphate: the Manitoba experience. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Saskatoon, 1993.

Peterdy AE, Maclean JP, McDonald DM, LESLIE WD. Radioactive iodine treatment of hyperthyroidism: effect of treatment dose on clinical outcome. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Saskatoon, 1993.

Kopelow M, Chochinov A, Schnabl G, Beazley G, Gill E, LESLIE WD, McPherson J, Moroz S, Morris M, Parker J, Schnabl G. Criterion reference standard setting in a standardized patient examination administered to graduating medical students. Presented at the 6th Ottawa Conference on Medical Education, June 1994.

Dupont JO, LESLIE WD, Peterdy AE, McDonald D. Low incidence of reversible septal defects in patients with LBBB: Dipyridamole versus exercise. Presented at the Conjoint Meeting of the Canadian Association of Nuclear Medicine and the Prairie Provinces Chapter, Society of Nuclear Medicine, Banff, 1994.

LESLIE WD, De Vos G, Boutcher S. Lack of correlation between cardiac enzyme elevations and planar pyrophosphate myocardial scans. Presented at the Conjoint Meeting of the Canadian Association of Nuclear Medicine and the Prairie Provinces Chapter, Society of Nuclear Medicine, Banff, 1994. Published in Clinical Nuclear Medicine 19(10):938, 1994.

LESLIE WD, Abrams D, Greenberg CR, Hobson D, McDonald D. A better mousetrap for dopamine D2 receptor imaging: Preliminary experience with iodine-123-epidepride. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Regina, 1995.

LESLIE WD, Dupont JO, McDonald D, Peterdy AE. Motion correction for cardiac SPECT: Some algorithms are more equal than others. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Regina, 1995

LESLIE WD, Riese KT, Dupont JO, Peterdy AE, McDonald D. An optimized imaging procedure for technetium-99m-sestamibi parathyroid scintigraphy. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Regina, 1995.

LESLIE WD, Cowden EA, Salamon E, Rowe RC, Ludwig S, McDonald D. Determination of therapeutic radioiodine dosages in Graves hyperthyroidism: A prospective randomized trial. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Regina, 1995.

Pearson E, Nance P, LESLIE WD, Ludwig S. The effect of cyclical etidronate on bone density in patients with acute spinal cord injury. Presented at the 64th Annual Meeting of the Royal College of Physicians and Surgeons of Canada.

LESLIE WD, Peterdy AE, McDonald D, Dupont JO. Radiation resistance in previously irradiated Grave's hyperthyroidism. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Banff, 1996.

LESLIE WD, McDonald D, Dupont JO, Peterdy AE. Automated registration using fiducial markers: A cure for disoriented brains. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Banff, 1996.

LESLIE WD, Thomson G, Dupont JO, McDonald D. Technetium-99m-IgG human immunoglobulin scintigraphy in the evaluation of sacroiliitis. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Banff, 1996.

McDonald DM, Peterdy AE, LESLIE WD, Ward LM. Determination of an optimum interval for follow-up bone density scans. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Banff, 1996.

Ward LM, LESLIE WD, McDonald DM. Comparison of two soft tissue equivalent methods for bone densitometry of the lower extremities. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Banff, 1996. Awarded the Elscint Award for Best Technologist Presentation.

LESLIE WD, Cowden EA, Salamon E, Rowe RC, Ludwig S. Determination of therapeutic radioiodine dosages in Graves hyperthyroidism: interim results of a prospective randomized trial. Presented at the Canadian Association of Nuclear Medicine Meeting, Quebec City, 1996.

Bybel B, LESLIE WD, Riese KT, Dupont JO, Peterdy AE, McDonald D. Tc99m-sestamibi parathyroid scintigraphy: Dual-tracer subtraction is superior to double-phase washout. Presented at the Canadian Association of Nuclear Medicine Meeting, Quebec City, 1996.

LESLIE WD, Greenberg CR, Abrams DA, Hobson D. Reduced dopamine D2 receptor density in Huntington Disease using [I-123]epidepride SPECT. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Winnipeg, 1997.

LESLIE WD, McDonald D, Short D, Dupont JO, Peterdy AE. Adiposity and polycythemia: interpretation of red blood cel mass measurements. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Winnipeg, 1997.

Havelock J, LESLIE WD, Palser R, Abrams D. Radiation dosease recevied by contacts of patients treated with radioactive I-131 for thyrotoxicosis. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Winnipeg, 1997.

Levin D, Johnson J, Jones D, LESLIE WD, Penner B. The home of wayward rats. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Winnipeg, 1997.

Peterdy, Dupont J, Ward L, LESLIE WD. The effect of filters of reproducibility of gated SPECT ejection fractions and volumes. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Winnipeg, 1997.

Choy JB, LESLIE WD. Correlation of technetium-99m-sestamibi lung uptake with coronary artery disease severity and left ventricular dysfunction. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Winnipeg, 1997.

Choy JB, LESLIE WD. Correlation of technetium-99m-sestamibi lung uptake with coronary artery disease severity and left ventricular dysfunction. Presented at the American College of Cardiology Meeting, Los Angeles, 1997. Published in The Journal of the American College of Cardiology February 1997; 261A.

Leslie WD, Dupont JO, Cowden EA, Salamon E, Rowe RC, Ludwig S. Radioiodine treatment of Graves hyperthyroidism: advances and retreats. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Saskatoon, 1998.

Dupont JO, Leslie WD, McDonald D. Pelvic uptake of [131-I]iodine in females. Presented at the Prairie Provinces Chapter Meeting, Society of Nuclear Medicine, Saskatoon, 1998.

Fine A, Henry S, LESLIE WD. Calciphylaxis: early presentation and successful treatment. XXXVII Congress of the ERA-EDTA European Renal Association, Nice, France, 2000.

LESLIE WD, Havelock S, Palser R, Abrams D. Large-body radiation doses following radioiodine therapy. Scientific Meeting of the Canadian Society of Nuclear Medicine, Mt. Tremblant, 2000.

DeVos G, Peterdy AE, Dupont JO, LESLIE WD. Effect of anithypertensive medication on incidence of captopril-induced symmetric renal transit abnormalities demonstrated on 99mTc-Mag3 renography. Scientific Meeting of the Canadian Society of Nuclear Medicine, Mt. Tremblant, 2000.

LESLIE WD, Havelock S, Palser R, Abrams D, Gordon K. Large-body radiation doses following radioiodine therapy. Scientific Meeting of the Canadian Radiation Protection Association, Montreal, 2000.

Sharma S, McLean L, Duerksen D, LESLIE WD, Sciberras D. Effects of anabolic steroids on patients with severe COPD undergoing pulmonary rehabilitation. Meeting of the American Thoracic Society, San Francisco, 2001.

Johnson HM and LESLIE WD. Dual energy X-ray absorptiometry. Meeting of the Canadian Radiation Protection Association, Halifax, 2001.

Metge C, Yuen CK, LESLIE WD, Yogendran M, Kvern B, Manness L-J. Using a population-based evidence-based disease management program to prevent and treat osteoporosis in postmenopausal women. Canadian Forum for Population Therapeutics, Edmonton, 2002.

LESLIE WD, Metge C, Ward L, Caetano P. Contribution of age and clinical risk factors in DXA-basd hip fracture risk stratification using a multidimensional model. Meeting of the International Osteoporosis Foundation, Lisbon, 2002.

Bernstein CN, LESLIE WD, Taback SP, Jacobs DL. Bone density (BMD) in a population-based cohort of premenopausal adult women who developed Crohn's disease as children. Digestive Disease Week Meeting of the American Gastroenterological Association, San Francisco, 2002.

Jeffery JR, LESLIE WD, Karpinski M, Nickerson P, Rush D. A randomized prospective trial of calcitriol versus alendronate for the treatment of osteopenia in renal transplant recipients. Meeting of the Canadian Transplant Society, Lake Louise, 2003.

Szwajcer D, LESLIE WD, Shojania AM, Metge C, Yogendran M. Clinical outcomes from low serum vitamin B12. Resident Research Day, University of Manitoba, Winnipeg, 2003.

Caetano PA, Metge, CJ, Leslie WD. The influence of bone mineral density testing on the initiation of an osteoporosis-related pharmacotherapy: A population-based analysis. ISPOR 9th Annual International Meeting, Arlington, 2004.

Szwajcer D, LESLIE WD, Shojania AM, Metge C, Yogendran M. The validation of an operational definition of cobalamin therapy derived from an administrative health database. Presented at Resident Research Day, University of Manitoba, Winnipeg, 2004.

Demeter S, LESLIE WD, Levin D. A Canadian National Survey - Physician Practice Patterns in Relation to Radioactive Iodine Therapy for Non-Malignant and Malignant Thyroid Disease. Presented at the annual meeting of the Canadian Society of Nuclear Medicine, Niagara-on-the-Lake, 2004.

Metge C, LESLIE W, Kvern B, Manness L, Yogendran M, Yuen CK. The burden and management of osteoporosis: A missed opportunity. Presented at the First Canadian Therapeutics Congress, Winnipeg, 2004.

Caetano PA, Metge CJ, LESLIE WD. The influence of bone mineral density testing on persistence and adherence to osteoporosis pharmacotherapy. Presented at the First Canadian Therapeutics Congress, Winnipeg, 2004.

LESLIE WD, Caetano PA, MacWilliam L, Lix L, Finlayson G. A population-based study of osteoporosis testing and treatment following introduction of a new bone densitometry service. Presented at the First Canadian Therapeutics Congress, Winnipeg, 2004.

LESLIE WD, Shabaga R. An analysis of replacement camera requirements for nuclear medicine (1992-2000). Prepared for the Provincial Nuclear Medicine Advisory Task Force, 1991.

Coauthor, prepared by the Provincial Nuclear Medicine Task Force, Nuclear Medicine Services: A 5-year plan

Kopelow M, Schnabl G, Chochinov A, Beazley G, Gill E, LESLIE WD, MacPherson J, Moroz S, Morris M, Parker J. Criterion referenced standard setting for a standardized patient examination. Proceedings of the Sixth Ottawa Conference on Medical Eduction. Arthur I Rothman and Robert Cohen (Editors).

LESLIE WD. Critical appraisal of performance characteristics of bone density measurement techniques. For the Scientific Advisory Committee, Osteoporosis Society of Canada, Consensus Conference on "Diagnosis of osteoporosis", Victoria, November 21-23 1997.

LESLIE WD. Commentary for Osteoporosis Update, Parkhurst Publishing, Winter 1999;3(1):6.

Contributing author to "Diagnostic Technologies: A Position Statement from the Osteoporosis Society of Canada". Osteoporosis Update, Parkhurst Publishing, Summer 1999;3(3):1-7.

LESLIE WD. Commentary for Osteoporosis Update, Parkhurst Publishing, Spring 2000;4(2):9.

Coauthor, prepared by the Provincial Nuclear Medicine Advisory Committee's PET Task Force, Clinical Positron Emission Tomography in Manitoba: A New Program Submission for the Winnipeg Regional Hospital Authority.

Methylxanthines and obstructive lung disease: A critique of the literature. Grand Rounds, Department of Medicine, St. Boniface General Hospital, 1988.

Advances in endocrine imaging. Grand Rounds, Department of Medicine, University of Manitoba, 1992.

Essentials of nuclear cardiology. Meeting of the Manitoba Association of Cardiac Technologists, Winnipeg, 1994.

Advances in parathyroid scintigraphy. Meeting of the Health Sciences Centre Nuclear Technologists, Winnipeg, 1994.

Radionuclide inflammatory imaging: Order from chaos. Grand Rounds, Department of Medicine, University of Manitoba, 1995

Nuclear perfusion imaging: Heart and brain. Grand Rounds, Department of Medicine, St. Boniface General Hospital, 1995.

Advances in brain SPECT scintigraphy. Grand Rounds, Neurosciences , St.Boniface General Hospital, 1995; Grand Rounds, Department of Radiology, Health Sciences Centre, 1995; National Research Council Biodiagnostics Laboratory, Winnipeg, 1996.

Osteoporosis 1995: Truths, myths and in between. Health Sciences Foundation Seminar "Women's Health Matters". Winnipeg, 1995.

Internal radiation therapy of thyroid cancer. National Canadian Refresher Course in Radiation Oncology, Winnipeg, 1995.

Diagnostic Testing in Osteoporosis. Grand Rounds, Department of Medicine, University of Manitoba, 1997.

Osteoporosis: An Overview of Bone Density Loss. Rehabilitation Challenges for the New Millenium, Winnipeg, 1999

Osteoporosis: Bone Density and Fracture Risk Assessment. Manitoba Chapter of the Osteoporosis Society of Canada, Winnipeg, 1999

Advances in nuclear cardiology. Meeting of the Manitoba Association of Cardiac Technologists, Winnipeg, 2001

Functional brain imaging in Huntington's Disease. Garrod/Western Group of Investigators Meeting, Winnipeg, 1994.

Functional brain SPECT. 52nd Annual General Conference of the Canadian Association or Medical Radiation Technologists, Winnipeg, 1994.

The role of nuclear medicine in the diagnosis of infectious disease. Symposium on Radiological Investigations in Infectious Disease and the 63rd Annual Meeting of the Royal College of Physicians and Surgeons of Canada, Toronto, 1994.

Advances in osteoporosis. Seventh Annual Symposium of the Manitoba Association of Asian Physicians, Winnipeg, 1996.

Diagnostic Testing in Osteoporosis. The Manitoba Clinic 50th Anniversary Symposium, Winnipeg, 1996.

Diagnosis and Assessment of Osteoporosis. "Osteoporosis in the 90's Symposium", Osteoporosis Society of Canada, Manitoba Chapter, Winnipeg, 1996.

Advances in Osteoporosis Diagnosis. Manitoba Saskatchewan Osteoporosis Interest Group, 1997.

Clinical Interpretation of Bone Densitometry. Osteoporosis Symposium. Banff, 1998.

Clinical Interpretation of Bone Densitometry. University of Manitoba CME. Selkirk, 1999.

Diagnosing Osteoporosis. CME for Family Physicians - "Osteoporosis", University of Manitoba CME. Winnipeg, 1999.

Clinical Aspects of Osteoporosis. 43rd Annual Meeting of the Canadian Society of Clinical Chemists, Winnipeg, 1999.

Fracture Risk. "Osteoporosis in Canada" Symposium and ISCD Physician & Technologist Certification Program, Toronto, 1999.

Practical Interpretation of BMD Reports. "Osteoporosis in Canada" Symposium, Toronto, 1999.

(Dys)functional brain imaging: a multimodal experience. Section of Nuclear Medicine, Ottawa Civic Hospital, 2001.

Fracture risk prediction: the Manitoba experience. Bone Metabolsim Group, Ottawa Civic Hospital, 2001.

PEER-REVIEWED PUBLICATIONS

Click the URL (Uniform Resource Locator) to view the abstract in the bottom frame.

LESLIE WD, Ward LM (2004). Bone density monitoring with the total hip site: Time for a re-evaluation? Journal of Clinical Densitometry 7(3):269-274, 2004.

Bernstein C, LESLIE WD (2004). Review article Osteoporosis and inflammatory bowel disease. Alimentary Pharmacology & Therapeutics 19(9):941-953, 2004.

LESLIE WD, Bernstein CN (2004). Response to letter to the Editor re AGA Technical Review on Osteoporosis in Hepatic Disorders. Gastroenterology 126(4):1226, 2004.

LESLIE WD, Tully SA, Yogendran MS, Ward LM, Nour KA, Metge CJ (2004). Prognostic value of automated quantification of technetium-99m sestamibi myocardial perfusion imaging. Journal of Nuclear Medicine, in press.

LESLIE WD, Tully SA, Yogendran MS, Ward LM, Nour KA, Metge CJ (2004). Automated quantification of technetium 99m sestamibi myocardial perfusion compared with visual analysis. Nuclear Medicine Communications, 25(8):833-838, 2004.

Khan AA, Bachrach L, Brown JP, Hanley DA, Josse RG, Kendler DL, Leib ES, Lentle BC, LESLIE WD, Lewiecki EM, Miller PD, Nicholson RL, O'Brien C, Olszynski WP, Theriault MYD, Watts NB (2004). Standards and guidelines for performing central dual-energy x-ray absorptiometry in premenopausal women, men, and children. Journal of Clinical Densitometry 7(1):51-63, 2004. URL = 14742888

LESLIE WD, MacWilliam L, Lix L, Caetano P, Finlayson GS (2004). A population-based study of osteoporosis testing and treatment following introduction of a new bone densitometry service. Osteoporosis International, in press.

Bernstein CN, LESLIE WD, Taback SP (2003). Bone density in a population-based cohort of premenopausal adult women with early-onset inflammatory bowel disease. American Journal of Gastroenterology 98(5):1094- , 2003. URL = 12809833

Bernstein CN, Bector S, LESLIE WD (2003). Lack of relationship of calcium and vitamin D intake to bone mineral density in premenopausal women with inflammatory bowel disease. American Journal of Gastroenterology 98(11):2468-2473, 2003. URL = 14638350

LESLIE WD, Metge C, Ward L (2003). Establishing a regional bone density program: lessons from the Manitoba experience. Journal of Clinical Densitometry 6(3):275-282, 2003.

Bernstein CN, LESLIE WD (2003). The pathophysiology of bone disease in gastrointestinal disease. Eur J Gastroenterol Hepatol 15(8):857-864, 2003. URL = 12867794

Jeffery JR, LESLIE WD, Karpinski ME, Nickerson PW, Rush DN (2003). Prevalence and Treatment of Decreased Bone Density in Renal Transplant Recipients: A Randomized Prospective Trial of Calcitriol versus Alendronate. Transplantation 76(10):1498-1502, 2003. URL = 14657693

LESLIE, William D., Colleen Metge (2003). Establishing a Regional Bone Density Program, Journal of Clinical Densitometry, Vol. 6, No. 3, 275-283, 2003. Full text pdf file

LESLIE WD, Metge C., Ward L (2003). Contriution of clinical risk factors to bone density-based absolute fracture risk assessment in postmenopausal women. Osteoporosis International 14:234-238, 2003. URL = 12730741

Bernstein CN, Bector S, LESLIE WD (2003). Lack of relationship of calcium and vitamin D intake to bone mineral density in premenopausal women with inflammatory bowel disease. American Journal of Gastroenterology in press.

LESLIE WD, Roe EB (2003). Preventing falls in elderly persons [letter]. New England Journal of Medicine 348(18):1816-1817, 2003.

Foga MM, LESLIE WD (2003). Gastrointestinal Bleeding - Munchausen Style. Clinical Nuclear Medicine 28(4):330-331, 2003.

Bernstein CN, LESLIE WD, LeBoff MS (2003). American Gastroenterological Association Medical Position Statement: Osteoporosis in Hepatic Disorders. Gastroenterology 125(3): 937-940, 2003. Full text pdf file.

Bernstein CN, LESLIE WD, LeBoff MS (2003). AGA Technical Review on Osteoporosis in Hepatic Disorders. Gastroenterology 125(3): 941-966, 2003. Full text pdf file.

Bernstein CN, LESLIE WD, LeBoff MS (2003). American Gastroenterological Association Medical Position Statement: Guidelines on Osteoporosis in Gastrointestinal Diseases. Gastroenterology 124(3):791-794, 2003. Full text pdf file.

Bernstein CN, LESLIE WD, LeBoff MS (2003). AGA Technical Review on Osteoporosis in Gastrointestinal Diseases. Gastroenterology 124(3):795-841, 2003. URL = 12629071. Full text pdf file.

LESLIE WD, Ward L. Salamon EA. Ludwig S. Rowe RC, Cowden EA (2003). A randomized comparison of radioiodine doses in Graves' hyperthyroidism. Journal of Clinical Endocrinology and Metabolism 88(3):978-983, 2003. URL = 12629071

Khan AA, Brown J, Faulkner K, Kendler D, Lentle B, LESLIE WD, Miller PD, Nicholson L, Olszynski WP, Watts NB. Reviewed by Canadian Panel members Hanley D. Hodsman A, Josse R, Murray TM, Yuen K (2002). Standards and guidelines for Performing Central Dual Energy X-Ray Densitometry from the Canadian Panel of the International Society for Clinical Densitometry. The Journal of Clinical Densitometry 5(4):435-445, 2002.

Brown JP, Josse RG, and the Scientific Advisory Council of the Osteoporosis Society of Canada (2002). 2002 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada. Canadian Medical Association Journal 167(10 Suppl):S1-S34, 2002.

Leslie WD, Dupont JO, Bybel B, Riese KT. (2002). Parathyroid 99mTc-sestamibiscintigraphy: Dual-tracer subtraction is superior to double-phase washout. Eur J Nucl Med Mol Imaging 29(12), 1566-1570. URL
= 12458389 (abstract) PDF file (full paper).

LESLIE WD, Havelock J, Palser R, Abrams D (2002). Large-body radiation doses following radioiodine therapy. Nuclear Medicine Communications 23:1091-1097, 2002. URL = 124118 38

Leslie, W.D., C. Metge, E.A. Salamon & C.K. Yuen (2002). Erratum : bone mineral density testing in healthy postmenopausal women: the role of clinical risk factor assessment in determining fracture risk. J Clin Densitom 5(3), 319. URL = 12357070 (no abstract available)

LESLIE WD, Metge C, Salamon EA, Yuen CK (2002). Bone mineral density testing in healthy postmenopausal women: the role of clinical risk factorassessment in determining fracture risk. The Journal of ClinicalDensitometry 2002;5(2):117-130. URL = 12110755

Foga, M.M. & W.D. Leslie (2002). Gastrointestinal bleeding. Clinical Nuclear Medicine, in press.

Khan, A.A., J.P. Brown, D.L. Kendler, W.D. Leslie, B.C. Lentle, E.M. Lewiecki, P.D. Miller, R.L. Nicholson, W.P. Olszynski & N.B. Watts (2002). The 2002 Canadian bone densitometry recommendations: take-home messages. Cmaj 167(10), 1141-1145. PDF file

Choy JB, LESLIE WD (2001). Clinical correlates of Tc-99m sestamibi lung uptake. The Journal of Nuclear Cardiology 2001;8(6):639-644. URL = 11725259

Leslie WD (2001). All patients with inflammatory bowel disease should havebone density assessment: Con. Inflammatory Bowel Diseases 2001;7(2):163-167.

Leslie, W.D., G. DeVos, J.O. Dupont & A.E. Peterdy (2001). Reproducibility of volume-adjusted bone mineral density of spine and hip from dual X-ray absorptiometry. J Clin Densitom 4(4), 307-312. URL = 11748335

Leslie, W.D., K.T. Riese & C. Mohamed (2000). Sestamibi retention in reactive lymph node hyperplasia: a cause of false-positive parathyroid localization. Clin Nucl Med 25(3), 216-7. URL = 20162251 (no abstract available)

Leslie, W.D., C.R. Greenberg, D.N. Abrams & D. Hobson (1999). Clinical deficits in Huntington disease correlate with reduced striatal uptake on iodine-123 epidepride single-photon emission tomography. Eur J Nucl Med 26(11), 1458-64. URL = 20020064

Leslie, W.D., J.O. Dupont & A.E. Peterdy (1999). Effect of obesity on red cell mass results. J Nucl Med 40(3), 422-8. URL = 99184510

Leslie, W.D., S. Wali & M. Kryger (1999). Blood flow of the middle cerebral artery with sleep-disordered breathing: correlation with obstructive hypopneas. Stroke 30(1), 188-90. Full text article - http://www.stroke.ahajournals.org/cgi/content/full/30/1/188/a

Leslie, W.D., A.E. Peterdy & J.O. Dupont (1998). Radioiodine treatment outcomes in thyroid glands previously irradiated for Graves' hyperthyroidism. J Nucl Med 39(4), 712-6. URL = 98204245

Leslie, W.D., J.O. Dupont, D. McDonald & A.E. Peterdy (1997). Comparison of motion correction algorithms for cardiac SPECT. J Nucl Med 38(5), 785-90. URL = 97314105

Pearson, E.G., P.W. Nance, W.D. Leslie & S. Ludwig (1997). Cyclical etidronate: its effect on bone density in patients with acute spinal cord injury. Arch Phys Med Rehabil 78(3), 269-72. URL = 97238011

Leslie, W.D., G.T. Thomson, J.O. Dupont & D. McDonald (1996). Technetium-99m-IgG polyclonal human immunoglobulin scintigraphy in the evaluation of sacroiliitis. Eur J Nucl Med 23 (10), 1416. URL = 97020099 (no abstract available)

Leslie, W.D., D.N. Abrams, C.R. Greenberg & D. Hobson (1996). Comparison of iodine-123-epidepride and iodine-123-IBZM for dopamine D2 receptor imaging. J Nucl Med 37(10), 1589-91. URL = 97015639

Stein, M.B. & W.D. Leslie (1996). A brain single photon-emission computed tomography (SPECT) study of generalized social phobia. Biol Psychiatry 39(9), 825-8. URL = 96301311

Leslie, W.D., K.T. Riese, R. Guzman, J.O. Dupont & A.E. Peterdy (1996). Technetium-99m-pertechnetate uptake by intrathyroidal parathyroid adenoma. J Nucl Med 37(5), 861-2. URL = 97096765

Leslie, W.D. (1996). Thyroid scintigraphy and perchlorate discharge test in the diagnosis of congenital hypothyroidism. Eur J Nucl Med 23(2), 230. URL = 97027562 (no abstract available)

Stern, S.S., W.D. Leslie, J.O. Dupont, A.E. Peterdy, M.W. Billinghurst & D.N. Abrams (1995). Hepatobiliary clearance of intravenous Tc-99m pertechnetate. Clin Nucl Med 20(11), 962-4. URL = 96146972

Leslie, W.D., K.T. Riese, J.O. Dupont & A.E. Peterdy (1995). Parathyroid adenomas without sestamibi retention. Clin Nucl Med 20(8), 699-702. URL = 96008968

Leslie, W.D., E.A. Cowden & J.P. Maclean (1995). Oestrogen and bone density: a comparison of tamoxifen and hypo-oestrogenaemia. Nucl Med Commun 16(8), 698-702. URL = 96048563

Leslie, W.D., A. Borys, D. McDonald, J.O. Dupont & A.E. Peterdy (1995). External reference markers for the correction of head rotation in brain single-photon emission tomography. Eur J Nucl Med 22(4), 351-5. URL = 95331334

Leslie, W.D. (1994). Stochastic variability in effective dose tissue weighting factors: a Monte Carlo study. Health Physics 67(1), 70-5. URL = 94259603

Leslie, W.D. & P.W. Nance (1993). Dissociated hip and spine demineralization: a specific finding in spinal cord injury. Arch Phys Med Rehabil 74(9), 960-4. URL = 93393421

Leslie, W.D., C. Reinhold, L. Rosenthall, C. Tau & F.H. Glorieux (1992). Panostotic fibrous dysplasia. A new craniotubular dysplasia. Clin Nucl Med 17(7), 556-60. URL = 92346978

Leslie, W.D. & I.D. Greenberg (1991). Reference range determination: the problem of small sample sizes. J Nucl Med 32(12), 2306-10. URL = 92079074

Leslie, W.D., D.N. Abrams & M.W. Billinghurst (1991). Elution characteristics of 99Tcm-labelled erythrocytes in relation to scintigraphic detection of gastrointestinal bleeding. Nucl Med Commun 12(11), 983-92. URL = 92093284

Leslie, W.D. & R.C. Brunham (1990). The dynamics of HIV spread: a computer simulation model. Comput Biomed Res 23(4), 380-401. URL = 90367467

1992	SPECT in the study of social phobia $13,500 for 1 year (Squibb Fellowship Fund) Primary applicant M. Stein
1992	Quantitative hepatobiliary scintigraphy in the assessment of Sphincter of Oddi dysfunction. $1,500 for 2 years (Squibb Fellowship Fund) Primary applicant J. Dupont
1992	Prevention of osteoporosis in patients with acute spinal cord injury. $88,601 for 1 year (National Centres of Excellence - Neural Regeneration and Recovery) Primary applicant P. Nance
1993	Dopamine receptor imaging Huntington's Disease $15,000 for 1 year (Health Sciences Research Foundation) Primary applicant W. Leslie
1995	Prevention of bone loss in acute spinal cord injury with intravenous pamidronate $US 100,500 for 2 years (Paraplegic Veterans Association Grant #1502) Primary applicant P. Nance
1995	Regional cerebral blood flow in obstructive sleep apnea $6,000 in radiopharmaceutical supplies (Dupont Pharma Clinical Grant #95031) Primary applicant W. Leslie
1997	Prevention of osteoporosis in acute spinal cord injury $US 55,465 for 1 year extension (Paraplegic Veterans Association Grant #1502) Primary applicant P. Nance
1998	Bone mineral density in Turner syndrome: Effect of growth hormone and estrogen therapy. $36,878 for 2 years (Children's Hospital Foundation of Manitoba, co-funded with Eli Lilly Canada, Inc) Primary applicant S. Taback; Co-Applicants G. Guyda, G. Van Vliet, J. Caminis, A. Tenenhouse, W. Lesli
1998	Bone mineral density in Turner syndrome: Effect of growth hormone and estrogen therapy. $50,000 for 2 years (Eli Lilly Canada, Inc, co-funded with Children's Hospital Foundation of Manitoba) Primary applicant S. Taback; Co-Applicants G. Guyda, G. Van Vliet, J. Caminis, A. Tenenhouse, W. Leslie
1999	Epidemiologic study of osteoporosis in aboriginal Manitobans $17,375 for 1 year (Health Sciences Centre Foundation) Primary applicant W. Leslie
1999	Maximizing Osteoporosis Management in Manitobans $1,000,000 over 3 years (Patient Health Management Program, Merck Frosst Canada) Primary applicant C.K. Yuen
1999	Bone health of young adults with juvenile rheumatoid arthritis. $79,944 over 2 years from The Arthritis Society Primary applicant S. Taback
2000	Bone Mineral Density in Turner Syndrome. $18,439 over 2 years (Children's Hospital Foundation of Manitoba) Primary Applicant S. Taback
2000	Bone Mineral Density in Turner Syndrome. $25,000 over 2 years (Eli Lilly Canada Inc.) Primary Applicant S. Taback
2001	The Role of the Amygdala and the Striatum in Social Anxiety Disorder and Obsessive Compulsive Disorder. $20,000 over 1 year (Manitoba Medical Service Foundation) Primary Applicant J. Sareen
2001	First Nations Bone Health Study $139,659 over 2 years (Canadian Institute for Health Research) $112,751 over 2 years (Manitoba Regional Partnerships Program) Primary applicant W. Leslie
2002	Understanding the biological, clinical and psychosocial determinants of health outcomes in inflammatory bowel disease: a research program. $1.4 over 5 years (Canadian Institute for HealthResearch) Primary applicant C.N. Bernstein
2003	Clinical determinants and fracture outcomes in Manitoba First Nations. $43,768. over 1 year (Canadian Institute for Health Research) Primary applicant: W.D. Leslie
2003	Clinical outcomes from low serum vitamin B12. $1,000. over 1 year (Health Sciences Centre Medical Staff Council Followship Fund) Primary applicant: D. Szwacjer (resident) and W.D. Leslie (supervisor)