Dr. Villar's research focuses on determining the underlying mechanisms involved in the cardiovascular, respiratory, and muscular integrative regulation to physiological challenges. More specifically, he uses postural changes and exercise as a framework to elucidate the role of perfusion pressure, O2 availability, and vascular conductance/resistance in the regulation of blood flow and O2 uptake and the implications for the muscular system especially the muscle pump.
Villar, R, Hughson, RL. Vascular conductance and muscle blood flow during exercise are altered by inspired oxygen fraction and arterial perfusion pressure. Physiol Rep. 2017 Mar; 5:5 2017. pii: e13144. doi: 10.14814/phy2.13144.
Villar, R, Gillis, J, Santana, G, Almeida, ALRA. Association between anaerobic metabolic demand during simulated Brazilian Jiu-Jitsu combat and specific Jiu-Jitsu anaerobic test. J Strength Cond Res. 2016 Jun 29. [Epub ahead of print]
Villar, R, Beltrame, T. Hughson, RL. Validation of the Hexoskin wearable body metrics vest during lying, sitting, standing and walking activities. Appl. Physiol. Nutr. Metab. 40: 1–6 (2015) dx.doi.org/10.1139/apnm-2015-0140
Villar R, Hughson RL. Effect of altered arterial perfusion pressure on vascular conductance and muscle blood flow dynamic response during exercise in humans. J Appl Physiol, 114(5):620-627, 2013.
Villar R, Hughson RL. Lower limb vascular conductance and resting popliteal blood flow during head-up and head-down postural challenges. Clin Physiol Funct Imaging, 33(3):186-191, 2013.
Villar R, Hughson RL. Repeatability of popliteal blood flow and lower limb vascular conductance at rest and exercise during body tilt using Doppler ultrasound. Physiol Meas., 34(3):291-306, 2013.
Beltrame T, Villar, R, Hughson, RL. Sex differences in the oxygen delivery, extraction and uptake during moderate walking exercise transition. Appl. Physiol. Nutr. Metab. doi: 10.1139/apnm-2017-0097.
Beltrame T, Amelard R, Villar R, Shafiee MJ, Wong A, Hughson RL. Estimating oxygen uptake and energy expenditure during treadmill walking by neural network analysis of easy-to-obtain inputs. J Appl Physiol (1985). 2016 Nov 1;121(5):1226-1233. doi: 10.1152/japplphysiol.00600.2016.