Dake Qi, MD, PhD

Research summary

Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine that is also expressed in non-immune cells. Dr. Qi’s laboratory currently aims to identify and test the role of MIF family proteins, including MIF and D-dopachrome tautomerase (DDT) in the development of metabolic dysfunction; and their roles in myocardial reperfusion injury associated with metabolic abnormalities. His lab uses molecular and cellular biological techniques combining with in vitro, ex vivo and in vivo models, such as isolated primary cells, the mouse Langendorff heart perfusion setup and ligation of the LAD (left anterior descending coronary artery) in the intact mice.
 

Research funding

• CIHR project grant
• NSERC discovery grant

College of Pharmacy research themes

• Biotargets and mechanisms of disease
• Translational pharmacotherapy and practice

Keywords

• Adipose tissue
• Atypical antipsychotic induced metabolic side-effects
• Heart
• Heart disease
• Insulin resistance
• Metabolic dysfunction