Dr. Serletis joined the Departments of Surgery and Pediatrics as a member of the Section of Neurosurgery in April 2016. His clinical specialties are in Epilepsy and Pediatric Neurosurgery. He is presently the Director of Epilepsy Surgery, and is also a Scientist at the Children’s Hospital Research Institute of Manitoba (CHRIM), where he currently directs the Manitoba Neurosurgery Laboratory.
Dr. Serletis’ lab focuses on the neuroengineering study of biosignals acquired in vivo from the human brain, including EEG and MRI-based signals, during the standard work-up of epilepsy patients with medically refractory seizures. Neuroengineering techniques drawing on nonlinear dynamics, complexity theory and fractal methods offer innovative strategies to the study of extra- and intra-cranial human EEG brain recordings, and may be used to identify novel mathematical markers underlying the transition to the epileptic state, with monitoring and/or therapeutic implications.
Dr. Serletis also holds diverse research interests in the study of neural networks servicing language, memory and other cognitive functions, that lend themselves to further study with intracranial electrodes. By combining improved imaging capabilities and intracranial EEG recordings, there is a wealth of knowledge to be gained in enhancing the understanding and characterization of 3D networks within the brain. Future research interests include virtual reality and simulation for educational purposes.
1. Serletis D. and T. G. Pait. “Early Craniometry as a Predecessor to Neurosurgical Stereotaxis.” Journal of Neurosurgery. 2016. 124:1867-74.
2. Albert, G.W. and D. Serletis. “Surgical Management of Epilepsy in Adolescent Patients.” Journal of Pediatric Epilepsy. 2015. 4:102-108.
3. Serletis D., J. Bulacio, W. Bingaman, I. Najm and J. Gonzalez-Martinez. “The Stereotactic Approach for Mapping Epileptic Networks: A Prospective Study of 200 Patients.” Journal of Neurosurgery. 2014. 121:1239-46.
4. Serletis D., J. Bulacio, A. Alexopoulos, I. Najm, W. Bingaman and J. Gonzalez-Martinez. “Tailored Uni- and Multi-lobar Resections for Orbito-Frontal-Plus Epilepsy.” Neurosurgery. 2014. 75:388-97.
5. Serletis D., P.L. Carlen, T.A. Valiante and B.L. Bardakjian. “Phase Synchronization of Neuronal Noise in Mouse Hippocampal Epileptiform Dynamics.” International Journal of Neural Systems. 2013. 23:1250013.
University of Manitoba
Associate Professor - Department of Surgery and Department of Pediatrics
Cross or adjunct appointments with other Departments
Department of Biomedical Engineering, Faculty of Engineering
Department of Physiology & Pathophysiology
Department of Surgery
Children's Hospital - Health Sciences
Association with a Research Institute
Children's Hospital Research Institute of Manitoba (CHRIM)