As a physicist specializing in magnetic resonance imaging (MRI), I am developing a non-invasive empirical method to diagnose Alzheimer's Disease and other nervous system disorders in their earliest stages. I am also using MRI to follow the effectiveness of treatment regimes over the course of time. (The image below the sort of imaging the group does.)
Beta-Amyloid Plaques Visualized In Vivo Without the Use of Contrast Agents. An axial section from a 3D T2*-weighted image of a transgenic mouse is shown in Figure a. Plaques are shown with arrows. The histological section is shown in Figure b. Figures c and d show a magnified version of a portion of the MRI and histological section respectively. Figure e shows a magnified version of the raw, unsmoothed MRI showing the location of the two punctate hypointense areas seen in Figure c.