Seth Marks

Current Leadership Positions

Associate Professor, Department of Pediatrics & Child Health
Section Head, Section of Pediatric Endocrinology and Metabolism
Medical Director, Diabetes Education Resource for Children & Adolescents (DER-CA)
Associate Head and Associate Medical Director, Department of Pediatrics & Child Health
Director (acting), Maestro Project
Canadian Pediatric Endocrine Group (CPEG), Scientific Planning Committee Chair, 2019 - 2021

Clinical Focus

Dr. Marks cares for children and their families living with diabetes or other endocrine diseases including disorders of growth, reproductive development, pituitary, adrenal, thyroid, bone, and glucose metabolism. He works as part of an interprofessional care team.


Master of Science, Medical Sciences- Pediatrics, University of Alberta, Edmonton, Alberta
Clinician Investigator Program, University of Alberta, Edmonton, Alberta
Fellowship in Pediatric Endocrinology (FRCPC), University of Alberta, Edmonton, Alberta
Residency in Pediatrics (FRCPC), McMaster University, Hamilton, Ontario
Doctor of Medicine (MD), University of Manitoba, Winnipeg, Manitoba
Bachelor of Science Degree – Dean’s Honour List, University of Manitoba, Winnipeg, Manitoba

Current Clinical Interests

  • General pediatric endocrine disease
  • Type 1 diabetes
  • Insulin pump therapy
  • Cystic Fibrosis Related Diabetes
  • Neonatal hypoglycemia
  • Neuroendocrine disease
  • Thyroid disease
  • Growth disorders
  • Administrative data


Creative Arts Diabetes Initiative: Group Art Therapy and Peer Support for Youth and Young Adults Transitioning from Pediatric to Adult Diabetes Care in Manitoba.
MacDonald C, Friedman S, Marks S.
Canadian Journal of Diabetes. In Press.

Screening guidelines for newborns at risk for low blood glucose.
Narvey M, Marks S, Canadian Paediatric Society Fetus and Newborn Committee.
Paediatrics and Child Health. In Press.

An uncommon initial presentation of a common disease.
Paediatrics and Child Health.
Marks SD, Silver S, Silver N. In Press.

Frequency and etiology of persistent neonatal hypoglycemia using the more stringent 2015 Pediatric Endocrine Society hypoglycemia guidelines.
Skovrlj R, Marks S, Rodd C.
Paediatrics and Child Health 2018. pxy166,

Growth hormone treatment of Canadian children: results from the GeNeSIS phase IV prospective, observational study.
Deal C, Kirsch S, Chanoine JP, Lawrence S, Cummings E, Rosolowsky E, Marks SD, Jia N, Child CJ, GeNeSIS National Board on behalf of the GeNeSIS Canada Investigators.
CMAJ Open 2018;6:e372-e383. (PMID 30201821)

Vigorous Intervals and Hypoglycemia in Type 1 Diabetes: A Randomized Cross Over Trial. 
Rempel M, Yardley J, MacIntosh A, Hay J, Bouchard D, Cornish S, Marks SD, Hai Y, Gordon JW, and McGavock J.
Scientific Reports 2018;8:15879. (PMID: 30367116)

Marked phenotypic variable expression among brothers with duplication of Xq27.1 involving the SOX3 gene.
Rosolowsky ET, Stein RS, Marks SD, Leonard N.
J Pediatr Endocrinol Metab 2015; online August 2015 ahead of print DOI:  10.1515/jpem-2015-0131. (PMID: 26352083)

A systematic review and meta-analysis of exercise interventions in adults with type 1 diabetes.
Yardley JE, Hay J, Abou-Setta AM, Marks SD, McGavock J.
Diabetes Res Clin Pract 2014;106:393-400. (PMID: 25451913)

Atypical diabetes: clarifying the muddy waters (Letter).
Sellers EAC, Marks S, Rodd C, Wicklow B, Dean H.
CMAJ 2014;186:1397. (eLetter:July 7 2014). (PMID: 25488736)

Vigorous Intensity Exercise for Glycemic Control in Patients with Type 1 Diabetes.
Yardley J, Mollard R, MacIntosh A, MacMillan F, Wicklow B, Berard L, Hurd C, Marks S, McGavock J.
Can J Diabetes 2013;37:427-432. (PMID: 24321725)

Health Care Costs for Initial Management of Children with New-Onset Type 1 Diabetes Mellitus in Central & Northern Alberta.
Foulds JL, Vanderloo SE, Marks SD, Johnson JA.
Can J Diabetes 2012;36:129-133. (

A Systematic Review on the Effect of Sweeteners on Glycemic Response and Clinically Relevant Outcomes.
BMC Medicine 2011;9:123. doi:10.1186/1741-7015-9-123
Wiebe N, Padwal R, Field C, Marks S, Jacobs R, Tonelli M.
Featured in a cross journal thematic series on Metabolism, Diet & Disease: and related conference in Washington DC from 29-31 May 2012.  (PMID: 22093544)

Identification of Two New Mutations in the Glucokinase Gene That Result in Maturity-onset Diabetes of the Young. 
Marks SD, Couch RM.
Diabetes Care 2010;33:e94 (PMID: 20587714).

Nonthyroidal illness syndrome in children.
Marks SD.
Endocrine 2009;36:355-367 (PMID: 19779866).

Hypothalamic-Pituitary-Thyroid Axis Changes in Children After Cardiac Surgery.
Marks SD, Haines C, Rebeyka IM, Couch RM.
The Journal of Clinical Endocrinology and Metabolism 2009; 94:2781-2786 [Featured in Endocrine News - A Publication of the Endocrine Society, August 2009]. (PMID: 19491228).

Childhood Onset Demyelination and Graves’ Disease: Shared Antigen or Autoimmune Clustering?
Mitchell RS, Yager JY, Marks SD.
Journal of Pediatric Endocrinology and Metabolism 2007;20:1233-1236 (PMID: 18183795).

In Children with Idiopathic Short Stature, What Advantage Does Administering Recombinant Growth Hormone Have Over Observation in Final Adult Height?
Marks SD.
Part B: Clinical commentary. Paediatrics and Child Health 2003;8:571. (PMID: 20019828)

Screening for Adrenal Antibodies in Children with Type 1 Diabetes and Autoimmune Thyroid Disease. 
Marks SD, Girgis R, Couch RM.
Diabetes Care 2003;26:3187-3188. (PMID: 14578262)

Thyroid Cancer in a Child Born After the Chernobyl Disaster.
Marks S, Girgis R, Couch R.
The Lancet Oncology 2002;3:527-528. (PMID: 12217789)

Book Chapters

Chapter 9: Update in Pediatric Endocrinology.
Marks SD, Wicklow BA.  
In: Piteau S (editor). Update in Pediatrics. Springer, Cham: April 2018:251-266.

Chapter 3: Diabetes in Children and Adolescents.
Johnson JA, Couch RM, Marks SD, Pacaud D. 
In Johnson JA, editor, Alberta Diabetes Atlas 2011. Edmonton:Institute of Health Economics;2011:25-34.

Chapter 16A: Endocrine.
Marks SD, MaAssey K.
In: Kirpalani H, Huang L (editors). Manual of Pediatric Intensive Care. Shelton: PMPH-USA 2009:534-579.

Awards & Honours

Top 10 Reviewers for 2018 - Canadian Journal of Diabetes (CJD), 2018.

The Annual Best Banting Gala Honouree – Presented to DER-CA, Canadian Diabetes Association, 2016.

Interdisciplinary Health-Care Team Award - Presented to DER-CA, College of Registered Nurses of Manitoba, 2015.

Seth Marks


Office phone: 204-787-7435

Mailing address:
FE307-685 William Avenue
Winnipeg, Manitoba R3E 0Z2