Dr. Hezhao Ji
 
Ji Hezhao

Adjunct Professor, Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Research Scientist, National HIV & Retrovirology Laboratories, National Microbiology Laboratory, Public Health Agency of Canada 

Degrees:
M.D. (Hebei, 1993); M.Sc. Medical Immunology (Hebei, 1996); Ph.D. Medical Microbiology & Infectious diseases (Manitoba, 2007)

Mailing Address:

JC Wilt Infectious Diseases Research Centre
Room J1123, 745 Logan Aveue
Winnipeg, MB, R3E 3L5

Tel:
(204) 789-6521 Fax: (204) 318-2221
E-mail: hezhao.ji@canada.ca
             Hezhao.Ji@umanitoba.ca

Research Interests:
Development of new methodologies for HIV diagnosis and HIV drug resistance testing;  HIV viral evolution and molecular HIV epidemiology; applications of next generation sequencing (NGS) technologies in HIV/AIDS; HIV/AIDS-revelant metagenomics studies.

Selected Publications:  

For a list of Dr. Ji's PubMed articles, please click here

  1. Ji H, Kozak RA, Biondi MJ, Pilon R, Vallee D, Liang B, La D, Kim J, Van Domselaar G, Leonard L, Sandstrom P, Brooks J. Next Generation Sequencing of the HCV NS5B Gene Reveals Potential Novel S282 Drug Resistance Mutations. Virology, 2015, 477: 1?9
  2. Sivro A, McKinnon LR, Ji H, Kimani J, Jaoko W, et al. Interferon Regulatory Factor 1 Polymorphisms Previously Associated with Reduced HIV Susceptibility Have No Effect on HIV Disease Progression. PLoS ONE 2013, 8(6): e66253. doi:10.1371/journal.pone.0066253
  3. Ji H, Liang B, Li Y, Van Domselaar G, Graham M, Tyler S, Merks H, Sandstrom P and Brooks J. Low abundance drug resistance variants in transmitted HIV drug resistance surveillance specimens identified using tagged pooled pyrosequencing. J Virol Methods 2013, 187, 314–320. [Epub ahead of print: doi:pii: S0166-0934(12)00382-5. 10.1016/j.jviromet.2012.10.018].
  4. Ji H, Li Y, Graham M, Liang B, Pilon R, MacPherson P, Van Domselaar G,Sandstrom P and Brooks J. Pyrosequencing Dried Blood Spots Reveals Differences in HIV Drug Resistance between Treatment Naïve and Experienced Patients. PLoS ONE 2013, 8(2): e56170. doi:10.1371/journal.pone.0056170.
  5. Liang B, Luo M, Scott-Herridge J, Semeniuk C, Mendoza M, Capina R, Sherdown B, Ji H, Kimani J,  Ball TB, Van Domselaar G, Graham M, Tyler S, Jones S and Plummer FA. A Comparison of Parallel Pyrosequencing and Sanger Clone-Based Sequencing and Its Impact on the Characterization of the Genetic Diversity of HIV-1. PLoS ONE 2011. 6(10): e26745.
  6. Ji H, Li Y, Graham M, Liang B, Pilon R, Tyson S, Peters G, Tyler S, Merks H, Bertagnolio S, Luis Soto-Ramirez L, Sandstrom P and Brooks J. Next Generation Sequencing of Dried Blood Spot Specimens: A Novel Approach to HIV Drug Resistance Surveillance. 2011;16(6):871-8
  7. Ji H, Massé N, Tyler S, Liang B, Merks H, Graham M, Sandstrom P and Brooks B. HIV Drug Resistance Surveillance Using Pooled Pyrosequencing. PLoS ONE  2010. 5(2):e9263.
  8. Ji H, Ball T B, Liang B B, Ao Z, Kimani J, Yao X and Plummer F A. Reduced HIV-1 long terminal repeat transcription in subjects with protective interferon regulatory factor-1 genotype: A potential mechanism mediating resistance to infection by HIV-1. Scand J Infect Dis2010. 42(5):389~394.
  9. Ji H, Ball T B, Liang B B, Kimani J and Plummer F A. Human Interferon Regulatory Factor-1 gene and its promoter sequences revealed by population-based complete gene sequencing.  DNA Seq 2008 Jun; 19 (3):  326-31.