Dr. Morag Graham
 

 
Adjunct Professor, Department of Medical Microbiology , University of Manitoba & Research Scientist (Genomics), National Microbiology Laboratory, Public Health Agency of Canada

Degrees: Ph.D. (Microbiology, Guelph , 2000); B.Sc. Cooperative (Hons.) (Biochemistry, Waterloo, 1990)

Mailing Address:Genomics Core, National Microbiology Laboratory, Public Health Agency of Canada 1015 Arlington St. , Winnipeg , MB , Canada R3E 3R2

Tel: (204) 789-7085, Lab: (204)789-6035, Fax: (204) 789-2018
E-mail: morag.graham@phac-aspc.gc.ca

Research Interests:
Comparative pathogenomics, molecular typing, biomarker discovery
Emerging pathogen characterization; Analysis of human microbial communities (microbiomes)
Host genetic variations associated with infectious disease susceptibility and therapeutic responses

Recent Publications:

For a list of Dr. Morag's publications, please click here

  1. 2005. Virtaneva* K, Porcella* SF, Graham MR, Ireland RM, Johnson CA, Romero RA, Gardner DJ, Bailey JR, Parnell MJ, and JM Musser, 2005. “Longitudinal Study of the Group A Streptococcus transcriptome, in vivo, during Acute Pharyngitis”.  Proc. Natl. Acad. Sci. USA. 102: 9014-9019.
  2. 2005. Sumby P, Porcella SF, Madrigal AG, Barbian KD, Virtaneva K, Ricklefs SM, Sturdevant DE, Graham MR, Vuopio-Varkila J, Hoe NP, and JM Musser. 2005. “Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events.” J Infect Dis. 192: 771-782.
  3. 2005.  MR Graham, Virtaneva K, Porcella SF, Barry WT, Gowen BB, Johnson CA, Wright FA, and JM Musser. 2005. “Group A Streptococcus transcriptome dynamics during growth in human blood reveals bacterial adaptive and survival strategies”.  Amer. J. Pathol. 166:455-465.
  4. 2006. Graham MR, Virtaneva K, Porcella SF, Barry WT, Gardner DJ, Long D, Welty D, Wright FA, and JM Musser. 2006. “Analysis of the Transcriptome of Group A Streptococcus in Mouse Soft Tissue Infection”. Amer. J. Pathol. 169: 927-942.
  5. 2007. Golding GR, Olson AB, Doublet B, Cloeckaert A, Christianson S, Graham MR, and MR Mulvey. 2007. The effect of the Salmonella genomic island 1 on in vitro global gene expression in Salmonella enterica serovar Typhimurium LT2.  Microbes and Infection. 9(1):21-27.
  6. 2009. Cutler J, Schleihauf E, Hatchette TF, Billard B, Watson-Creed G, Davidson R, Li Y, Bastien N, Sarwal S, and the Nova Scotia Human Swine Influenza Investigation Team.  2009.  Investigation of the first cases of human-to-human infection with the new swine-origin influenza a (H1N1) virus in Canada.  Canadian Medical Association Journal. 181: 159-163.
  7. 2010. Ji H, Massé N, Tyler S, Liang B, Li Y, Merks H, Graham M, Sandstrom P, and J Brooks. 2010.  “HIV Drug Resistance Surveillance Using Pooled Pyrosequencing”.  PLoS ONE. 2010 Feb 17;5(2):e9263.
  8. 2010. Gilmour MW, Graham M, Van Domselaar G, Tyler S, Kent H, Trout-Yakel KM, Larios O, Allen V, Lee B, and C. Nadon.  2010. “High-Throughput Genome Sequencing of two Listeria monocytogenes Clinical Isolates during a Large Foodborne Outbreak”.  BMC Genomics. 2010, 11:120 doi:10.1186/1471-2164-11-120
  9. 2010. Golding GR, Bryden L, Levett PN, McDonald RR, Wong A, Wylie J, Graham M, Tyler S, Van Domselaar G, Simor AE, Gravel D, and Mulvey MR. 2010.  “Livestock-associated Methicillin-Resistant Staphylococcus aureus  Sequence Type 398 in Humans, Canada”. Emerg Infect Dis. 2010 Apr;16(4):587-94.
  10. 2010. Bastien N, Antonishyn NA; Brandt K, Wong CE, Chokani K, Vegh N, Horsman GB, Tyler S, Graham MR, Plummer FA, and Yan Li. 2010. “Human Infection with a Triple Reassortant Swine Influenza A (H1N1) containing HA and NA of Seasonal Influenza”.  J Infect Dis. 2010 Apr 15;201(8):1178-82. \2010. Shea PR,  Virtaneva K, Kupko 3rd JJ, Porcella SF, Barry WT, Wright FA, Carmody A, Ireland RM,  Sturdevant DE, Ricklefs SM,  Babar I, Johnson CA, Graham MR, Gardner DJ, Bailey JR, Parnell MJ, DeLeo FR. and JM Musser.  2010.  “Interactome analysis of longitudinal pharyngeal infection of cynomolgus macaques by group A Streptococcus”. Proc Natl Acad Sci U S A. 2010. Mar 9;107(10):4693-8. Epub 2010 Feb 23.
  11. 2011. Graham M, Liang B, Van Domselaar G, Beaudoin C, Bastien N, Tyler S, Kaplen B, Landry E, the National Influenza A/H1N1pdm Genomics Study Team (NIGST), and Yan Li. “Nationwide Molecular Surveillance of Pandemic H1N1 Influenza A Virus Genomes: Canada, 2009”.  PLoS ONE.  In Press.
  12. 2011. Ji H, Li Y, Graham M, Liang B, Pilon R, Tyson S, Peters G, Tyler S, Merks H, Bertagnolio S, Soto-Ramirez L, Sandstrom P, and J Brooks*.  “Pooled Pyrosequencing of Dried Blood Spot Specimens - A Novel Approach to Efficient HIV Drug Resistance Surveillance in Resource Limited Settings”. Antiviral Therapy.  In Press.

Laboratory Members: (204) 789-6035

Christne Bonner Jacqueline Donogh Erika Landry Brynn Kapen
Kimberly Melanchuk  Travis Murphy Claude Ouellette Geoff Peters
Shaun Tyler Shari Tyson Vanessa Wolf Adrian Zetner