Research Scientist, National Laboratory for HIV Immunology, PHAC
Adjunct Professor, Department of Medical Microbiology & Infectious Diseases
One of our current projects is looking at the epigenome of genes in primary airway epithelial cells, exposed to different strains of H1N1 viruses. The epigenomic data is correlated with gene expression profiles to identify the genes that were permitted or silenced by H1N1 infection.
Another project is examining regulators of epigenetic markings (e.g. SWI/SNF, HP1-alpha, -gamma, HDAC-1,-2,-3, p300…) in immune cells in the blood and in mucosal sites.
Another 2 projects are examining the epigenetic regulation of IRF genes at promoter and enhancer regions and also the regulation of HIV promoter (the LTR region).
Public Health Agency of Canada (PHAC)