News and Events

2017 April - June

Dr. Shyamala Dakshinamurti (PI) and Dr. Prashen Chelikani (Co-PI) received an operating grant from Children's Hospital Research Institute of Manitoba (CHRIM), ($40,000).
Title: Gene Expression Profile of Smooth Muscle Contraction and Relaxation pathways in Hypoxic Persistent Pulmonary Hypertension of the Newborn.

Dr. Prashen Chelikani (PI) and Dr. Bob Schroth (Co-PI) received an operating grant from Children's Hospital Research Institute of Manitoba (CHRIM), ($40,000).
Title: The etiology of genes involved in taste signaling in determining young children's susceptibility to severe early childhood caries.
Dr. Silvia T. Cardona (PI) received a Mid Career Operating Grant from Research Manitoba (RM), 2 year ($146,700).
Title: Elucidation of the mechanism of action of a novel antibiotic targeting cell division
Dr. Ayush Kumar received an operating grant from CIHR, 5 year ($623,475).
Title: Studying microbial load and antibiotic resistance genes in source and drinking water from First Nation Reserves

Dr. Ayush Kumar received a URGP grant ($7,411).
Title: Characterizing a master switch of multidrug resistance and virulence in Acinetobacter baumannii
Three pilot grants ($7,000 each) from the following MCSB members were funded for 2017-18.

Drs. Ayush kumar and Silvia Cardona
Title: Designing CRISPR-based next-generation antimicrobials for Acinetobacter baumannii

Drs. Kangmin Duan and John Sorenson
Title: Synthesis and biological assessment of anti-virulence compounds- potential drug leads for bacterial infections
Drs. Shyamala Dakshinamurti and Prashen Chelikani
Title: Vasoactive Receptor Expression Patterns in Neonatal Pulmonary Hypertension

2017 January - March
Dr. Rotimi Aluko received the 2017 Fellow Award from the Institute of Food Technologists (IFT).
Dr. Bob Schroth (PI) and his team received a 3-year CIHR Team Grant: Pathways implementation Research Team - Component 2 -Oral Health Pool, ($900,000).
Title: Scaling up the Healthy Smile Happy Child initiative: tailoring and enhancing a community development approach to improve early childhood oral health for First Nations and Metis children.
Dr. Prashen Chelikani received a 2-yr operating grant from Cystic Fibrosis Canada, $196,000.
Title: Role of chemosensory bitter taste receptors (T2Rs) in cystic fibrosis.
Dr. Ayush Kumar (PI) and Drs. Kangmin Duan and George Hausner (Co-PIs) received a 1-yr University Collaborative Research Program (UCRP) operating grant, $25,0000.
Title: Purification and characterization of a novel antibiotic compound from a fungal isolate.

2016 July - December
Grants funded
Dr. Ayush Kumar received a CIHR project grant, $100,000. 
Title: Functional and Biochemical Characterization of the Assembly of Multidrug Resistance Tripartile Pump in Pseudomonas aeruginosa.
Dr. Prashen Chelikani received a 2-yr MITACS Accelerate Cluster grant, $416,000.
(Co-applicant: Dr. Anthony Iacopino)
Title: Enhanced and Conformation Specific G protein-coupled receptors (GPCRs) Expression for Autoimmune Diagnostics.
Three pilot grants from the following MCSB members were funded on a matching basis with other funding sources.
Drs. Ayush kumar and Kangmin Duan
Title: Purification and characterization of a novel antibiotic compound from a fungal isolate.
Drs. John Sorenson, Shyamala Dakshinamurti and Raj Bhullar
Title: The design and synthesis of isoform selective activators of adenylyl cyclase and the effect on persistent pulmonary hypertension of the newborn.
Drs. Rotimi Aluko and Prashen Chelikani
Title: Sensors for the electronic tongue (e-tongue)

Media articles

Dr. Prashen Chelikani's opinion on bitter blockers in Metronews and WIRED magazine
Dr. Ayush Kumar's discovery of novel hybrid antibiotics, news article

2016 April – June

Dr. Bob Scroth received a 4-yr CIHR Embedded Clinician Researcher Salary Award, $300,000.

Title: Improving access to oral health care and oral health care delivery for vulnerable young children in Manitoba.

Dr. Shyamala Dakshinamurti received a 2-yr mid-career operating grant from Research Manitoba, $150,000.
Title: Pulmonary Arterial Hypoxia and Adenylyl Cyclase Mediated Signaling in Neonatal Pulmonary Hypertension.
Dr. Ayush Kumar's discovery of antibiotic resistance bacteria in a Manitoba First Nation's water, news article on
CBC and CTV news

2016 January – March


Dr. Rotimi Aluko (along with Dr. Peter Jones) received a 3-yr operating grant from the Heart and Stroke Foundation of Canada, $232,148. 
Title: Evaluating the anti-hypertensive properties of whole hemp (Cannabis sativa L.) protein and hemp protein hydrolysate derived bioactive peptides in healthy participants with mild or moderate hypertension.
Dr. Bob Scroth (along with PIs Drs Martin Chartier and Mary Mcnally) received a 2-yr operating grant from CIHR. $250,000.

Title: A mixed methods evaluation of Health Canada's Children's Oral Health Initiative (COHI). Does it lead to improved oral health for young First Nations and Inuit children?
PhD Candidate Ms. Anjali Bhagirath secured second place in the 2016 Three Minute Thesis (3MT) competition at University of Manitoba.
MCSB Graduate students Ms. Anjali Bhagirath and Crystal Sidhu received prizes for oral and poster presentations at the Dentistry Research Day, Annual Manitoba Dental Association Convention, Convention Centre, Winnipeg. January 2016.



2015 October – December

Former Alumni of Dr.Chelikani's lab, Dr. Sai Prasad Pydi recieves the NIDDK Nanacy Nossal Fellowship Award at National Institutes of Health (NIH), USA

Graduate student Ifeanyi D. Nwachukwu from Dr. Rotimi Aluko’s lab is one of the 2015 Vanier Scholars.

Dr. Chelikani’s opinion on the taste of Nutella in Maclean's magazine, November 2015.

Dr. Kumar’s interview on 680CJOB discussing the problems of antibiotic resistance