News and Events

2018 July - December

NEWS

Dr. Shyamala Dakshinamurti
(PI), Drs. John Sorenson and Prashen Chelikani (Co-PIs) project was selected in a dragon's den type crowd-funding competition under the "Innovators" program of the Children's Hospital Research Foundation from a field of four clinical or research projects.
Title: Looking for keys to treat blue babies. This was featured on Global news and CTV.

Dr. Silvia Cardona (PI), Dr. Rebecca Davis (co-PI), and Dr. Pingzhao Hu (Co-PI) received a Pilot and Feasibility Award from from the American Cystic Fibrosis Foundation (CFF).
Title: Antibiotic discovery for Burkholderia cepacia complex

Dr. Shyamala Dakshinamurti (PI), Drs. John Sorenson and Prashen Chelikani (Co-PIs) received bridge funding from VPRIO for 1 year.
Title: Pulmonary arterial hypoxia and impaired adenylyl cyclase activity in neonatal pulmonary.

Dr. Robert Schroth (Co-PI) received a grant "Susceptibility of Indigenous North American children to severe early childhood caries. The Forsyth Institute Collaborative Pilot Grant. $250,000 US (2018-2020 RJ Schroth (Co-investigator); M Pugach (Principal Investigator (PI); FB Wiedemann-Bidlack (Co-PI); X He (Co-PI); J Starr (Co-Investigator); K Maguire (Co-Investigator); W Shi (consultant))."

Dr. Robert Schroth (PI) received a grant "Equipping a functioning dental clinical research suite for studies relating to early childhood caries and early childhood oral health" from the University of Manitoba Small Research Equipment Funding (SREF) Program. $21,010.

Dr. Robert Schroth (PI) received funding for "Pilot Validation of a New Canadian Pediatric Risk Assessment Tool (CANA-P) for Preschool Children. Seed Grant". Network for Canadian Oral Health Research (NCOHR). $20,000 (2018-2019 R Schroth (PI); Co-Investigators: M Brondani, M Bertone, M Sturym, A Finch; Knowledge Users: J Taylor, L Dufour, A Burry.

Dr. Robert Schroth is collaborator/consultant on a grant "The Impact of Prenatal Vitamin D supplementation on Prenatal Vitamin D Concentrations and Early Childhood Caries". Native American Research Centres for Health (NARCH) – Department of Health and Human Services, Indian Health Service. $483,823 US (2018-2020 R Schroth (Collaborator/Consultant)); ED Ferucci (Principal Investigator (PI)); Collaborator/Consultants: R Singleton, L Ward, KE Thummel, G Day, C Desnoyers.

Dr. Shyamala Dakshinamurti invited to chair the Canadian National Perinatal Research Meeting in 2020.

Dr. Anjali Yadav was awarded a one-year postdoctoral research fellowship from Research Manitoba/CHRIM (Co-supervisors: Drs. Dakshinamurti and Chelikani).

MEDIA

Dr. Cardona’s laboratory was featured by CTV news

Dr. Dakshinamurti was featured on Global news and CTV news


2018 January - July

NEWS

Dr. Prashen Chelikani (NPI), Dr. Robert Schroth (PI), and Drs. Kangmin Duan and Pingzhao Hu (Co-PIs) received a project grant from CIHR, five-year ($885,870).
Title: Role of taste signaling and host-microbial interactions on caries risk in young children.

Dr. Rotimi Aluko was the guest editor for an issue titled “Functional Foods and Nutrition” in Current Opinion in Food Science.

Dr. Rotimi Aluko was honoured with the American Oil Chemists’ Society “Fellow” Award at the annual conference in Minneapolis, May 6-9 2018. Click here to read the article.

Dr. Ayush Kumar was elected as the second Vice-President of the Canadian Society of Microbiologists (CSM) in June 2018. He will be the President of CSM in the year 2020.

Dr. Ayush Kumar received the University of Manitoba-UMFA Merit Award (2017) for Combination of Teaching; Service; and Research, Scholarly Work, and Other Creative Activities.

MEDIA

An article published by Drs. Rotimi Aluko and Prashen Chelikani in the Journal of Agricultural and Food Chemistry was the subject of a special American Chemical Society global news release titled: Beef peptides block bitter tastes. Click here to read the news release

Dr. Ayush Kumar’s laboratory was featured by Shaw TV Winnipeg. Click here to watch story

Vanessa Kornelsen (Dr. Ayush Kumar’s laboratory) wrote an article for the Winnipeg Free Press, “Choose antibiotic-free meat and poultry products” Click here to access the article

Appalaraju Jaggupilli (Dr. Chelikani lab) successfully defended his PhD on July 16th and received a MITACS Elevate PDF. On of his articles showing how taste receptors detect quorum sensing molecules, and act as sensors for bacterial signals was featured as Covert art for the July issue of CACS Infectious Diseases.


2017 July - December

Dr. Rotimi Aluko has been named to the list of 2017 Highly Cited Researcher in the Agricultural Sciences category by Thomson Reuter’s Clarivate Analytics. The recognition is for his multiple publications over the past eleven years that rank globally in the top 1 per cent by citations for field and publication year in Web of Science. According to the citation “Highly Cited Researchers are leading the way in solving the world’s biggest challenges.” Full list of researchers can be found here.

You can also watch the video of what it means to be a highly cited researcher, click here to watch video

Dr. Robert Schroth received the Canadian Association of Public Health Dentistry’s Public Service Award in September 2017.

Dr. Ayush Kumar and Dr. Kangmin Duan edited a topical issue for the Journal of Membrane Biology (Springer-Nature)
Title: Bacterial Membrane Proteins: Signal transduction, antibiotic resistance and virulence click here to read article.

Dr. Ayush Kumar (PI) received an operating grant from Cystic Fibrosis Foundation (US$ 98,800)
Title: Assembly of tripartite multidrug efflux pumps in Pseudomonas aeruginosa

Dr. John Sorenson (PI), Dr. Shyamala Dakshinamurti and Dr. Prashen Chelikani (Co-PIs) received an operating grant from the University Collaborative Research Program ($25,000)
Title: The synthesis of isoform selective activators of adenylyl cyclase and their effect on pulmonary hypertension of the newborn

Dr. Prashen Chelikani (PI) and Dr. Rotimi Aluko (Co-PI) received an operating grant from the University Collaborative Research Program ($25,000).
Title: Pea protein hydrolysates as bitter taste modifiers.

Dr. Prashen Chelikani (PI) received an equipment grant from the University of Manitoba RFHS and SREF ($75,000).
Title: FlexStation 3 Multimode Microplate Reader (Trade-in)

Dr. Robert Schroth (PI) along with colleagues and the Healthy Smile Happy Child partnership received an operating grant from Manitoba Dental Foundation ($7,500)
Title: Healthy Smile Happy Child initiative

MEDIA

Dr. Robert Schroth’s research work highlighted by CBC. Winnipeg dentist turning baby teeth black — to keep kids out of surgery. Silver diamine fluoride a low-cost way to halt (but not fix) tooth decay. Click here to watch story.

Dr. Ayush Kumar wrote an Op-Ed article for the Winnipeg Free Press, “Do cleaning products pose a threat to our health?” Click here to read article.


2017 April - June

Dr. Shyamala Dakshinamurti (PI) and Dr. Prashen Chelikani (Co-PI) received an operating grant from Children's Hospital Research Institute of Manitoba (CHRIM), ($40,000).
Title: Gene Expression Profile of Smooth Muscle Contraction and Relaxation pathways in Hypoxic Persistent Pulmonary Hypertension of the Newborn.

Dr. Prashen Chelikani (PI) and Dr. Bob Schroth (Co-PI) received an operating grant from Children's Hospital Research Institute of Manitoba (CHRIM), ($40,000).
Title: The etiology of genes involved in taste signaling in determining young children's susceptibility to severe early childhood caries.

Dr. Silvia T. Cardona (PI) received a Mid Career Operating Grant from Research Manitoba (RM), two-year ($146,700).
Title: Elucidation of the mechanism of action of a novel antibiotic targeting cell division

Dr. Ayush Kumar received an operating grant from CIHR, five-year ($623,475).
Title: Studying microbial load and antibiotic resistance genes in source and drinking water from First Nation Reserves

Dr. Ayush Kumar received a URGP grant ($7,411).
Title: Characterizing a master switch of multidrug resistance and virulence in Acinetobacter baumannii
Three pilot grants ($7,000 each) from the following MCSB members were funded for 2017-18.

Drs. Ayush kumar and Silvia Cardona
Title: Designing CRISPR-based next-generation antimicrobials for Acinetobacter baumannii

Drs. Kangmin Duan and John Sorenson
Title: Synthesis and biological assessment of anti-virulence compounds- potential drug leads for bacterial infections

Drs. Shyamala Dakshinamurti and Prashen Chelikani
Title: Vasoactive Receptor Expression Patterns in Neonatal Pulmonary Hypertension


2017 January - March

Dr. Rotimi Aluko received the 2017 Fellow Award from the Institute of Food Technologists (IFT).

Dr. Bob Schroth (PI) and his team received a three-year CIHR Team Grant: Pathways implementation Research Team - Component 2 - Oral Health Pool, ($900,000).
Title: Scaling up the Healthy Smile Happy Child initiative: tailoring and enhancing a community development approach to improve early childhood oral health for First Nations and Metis children.

Dr. Prashen Chelikani received a 2-yr operating grant from Cystic Fibrosis Canada, $196,000.
Title: Role of chemosensory bitter taste receptors (T2Rs) in cystic fibrosis.

Dr. Ayush Kumar (PI) and Drs. Kangmin Duan and George Hausner (Co-PIs) received a one-year University Collaborative Research Program (UCRP) operating grant, $25,0000.
Title: Purification and characterization of a novel antibiotic compound from a fungal isolate.


2016 July - December

GRANTS

Dr. Ayush Kumar received a CIHR project grant, $100,000.
Title: Functional and Biochemical Characterization of the Assembly of Multidrug Resistance Tripartile Pump in Pseudomonas aeruginosa.

Dr. Prashen Chelikani received a two-year MITACS Accelerate Cluster grant, $416,000.
(Co-applicant: Dr. Anthony Iacopino)
Title: Enhanced and Conformation Specific G protein-coupled receptors (GPCRs) Expression for Autoimmune Diagnostics.

Three pilot grants from the following MCSB members were funded on a matching basis with other funding sources.

Drs. Ayush Kumar and Kangmin Duan
Title: Purification and characterization of a novel antibiotic compound from a fungal isolate.

Drs. John Sorenson, Shyamala Dakshinamurti and Raj Bhullar
Title: The design and synthesis of isoform selective activators of adenylyl cyclase and the effect on persistent pulmonary hypertension of the newborn.

Drs. Rotimi Aluko and Prashen Chelikani
Title: Sensors for the electronic tongue (e-tongue)

MEDIA

Dr. Prashen Chelikani's opinion on bitter blockers in Metronews and WIRED magazine

Dr. Ayush Kumar's discovery of novel hybrid antibiotics, news article


2016 April – June

Dr. Bob Scroth received a 4-yr CIHR Embedded Clinician Researcher Salary Award, $300,000.
Title: Improving access to oral health care and oral health care delivery for vulnerable young children in Manitoba.

Dr. Shyamala Dakshinamurti received a two-year mid-career operating grant from Research Manitoba, $150,000.
Title: Pulmonary Arterial Hypoxia and Adenylyl Cyclase Mediated Signaling in Neonatal Pulmonary Hypertension.

Dr. Ayush Kumar's discovery of antibiotic resistance bacteria in a Manitoba First Nation's water, news article on CBC and CTV news


2016 January – March

Dr. Rotimi Aluko (along with Dr. Peter Jones) received a three-year operating grant from the Heart and Stroke Foundation of Canada, $232,148.
Title: Evaluating the anti-hypertensive properties of whole hemp (Cannabis sativa L.) protein and hemp protein hydrolysate derived bioactive peptides in healthy participants with mild or moderate hypertension.

Dr. Bob Scroth (along with PIs Drs Martin Chartier and Mary Mcnally) received a two-year operating grant from CIHR. $250,000.
Title: A mixed methods evaluation of Health Canada's Children's Oral Health Initiative (COHI). Does it lead to improved oral health for young First Nations and Inuit children?

PhD Candidate Ms. Anjali Bhagirath secured second place in the 2016 Three Minute Thesis (3MT) competition at University of Manitoba.

MCSB graduate students Ms. Anjali Bhagirath and Crystal Sidhu received prizes for oral and poster presentations at the Dentistry Research Day, Annual Manitoba Dental Association Convention, Convention Centre, Winnipeg. January 2016.


2015 October – December

Dr. Sai Prasad Pydi, alum of Dr. Chelikani's lab, recieves the NIDDK Nanacy Nossal Fellowship Award at National Institutes of Health (NIH), USA

Graduate student Ifeanyi D. Nwachukwu from Dr. Rotimi Aluko’s lab is one of the 2015 Vanier Scholars.

Dr. Chelikani’s opinion on the taste of Nutella in Maclean's magazine, November 2015.

Dr. Kumar’s interview on 680CJOB discussing the problems of antibiotic resistance