Dr. Michel Aliani

Position: Professor
                Adjunct Professor in the Department of Physiology and Pathophysiology

University of Manitoba
Department of Human Nutritional Sciences
W575 Duff Roblin Building
Winnipeg, MB R3T 2N2 Canada

St Boniface Hospital Research Center
351 Taché Ave.
Winnipeg, MB, R2H 2A6 Canada

Phone No.:
(204) 474-8070 / (204) 235-3048
Fax No.: (204) 474-7592

E-mail: michel.aliani@umanitoba.ca


Engineering degree in Agri-Food Biochemistry, CNAM, Paris, France
Ph.D. Queen’s University Belfast, UK.

Areas of Specialization:

  • Metabolomics
  • Meat Chemistry and Biochemistry
  • Mass Spectrometry and NMR techniques (HPLC, GC-MS, LC-MS-QTOF, LC-MS-NMR)
  • Sensory Evaluation of Food and Flavour Chemistry

Research Interests:

Development of acceptable functional foods destined to clinical trials

Metabolomics studies of biological fluids collected from nutritional interventions (animal and human studies) using LC-QTOF-MS, GC-MS and LC-MS-NMR techniques

Interview with CBC News:

What exactly are "natural flavours"?


Consumers are often reassured when their products contain "natural flavours", even if they're not really sure what they are. CBC's Blair Sanderson has a taste for answers.
Aired: Dec. 11, 2019


Current Research Projects

Title: Elucidating the role of low molecular weight peptides (< 1 kDa) as Maillard reactant flavour precursors in selected white and red meats using a flavouromics approach
Agency: NSERC Discovery Grant (2014-2019).

Title: Urinary and plasma metabolomics studies of fully characterized Saskatoon berry powder (SBP) fortified yogurt in healthy individuals
Agency: MAHRN (2015-2018).

Selected Publications:

R. Fahmi, D. Ryland, E. Sopiwnyk, M. Aliani. Sensory and physical characteristics of pan bread fortified with thermally treated split yellow pea (Pisum sativum L.) flour, Journal Food Science. Accepted, In Press (2019).

N. Ahmed, B. Kidane, L. Wang, G. Qing, L. Tan, G. Buduhan, S. Srinathan and M. Aliani. Non-invasive exploration of metabolic profile of lung cancer with Magnetic Resonance Spectroscopy and Mass Spectrometry, Contemporary Clinical Trials Communications 16 (2019) 100445.

Surendran A, Aliani M and Ravandi A, Metabolomic characterization of myocardial ischemia-reperfusion injury in ST-segment elevation myocardial infarction patients undergoing percutaneous coronary intervention. Scientific Reports Nature Research 9:doi.org/1038/s41598-41019-48227-41599 (2019).

Stamenkovic A, Ganguly R, Aliani M, Ravandi A and Pierce G, Overcoming the Bitter Taste of Oils Enriched in Fatty Acids to Obtain Their Effects on the Heart in Health and Disease. Nutrients 11:doi:10.3390/nu11051179  (2019).

Parikh M, Maddaford TG, Austria JA, Aliani M, Netticadan T and Pierce GN, Dietary Flaxseed as a Strategy for Improving Human Health. Nutrients 11:doi:10.3390/nul11051171 (2019).

S. Clark, D.D. Ramdath, B.V. King, K.E. O'Connor, M. Aliani, A. Hawke, A. Dunkan, Food type and lentil variety affect satiety responses but not food intake in healthy adults when lentils are substituted for commonly consumed carbohydrates, The Journal of Nutrition Accepted In Press (2019).

K.J. McClinton, M. Aliani, S. Kuny, Y. Sauve, M. Suh, Differential effect of a carotenoid-rich diet on retina function in non-diabetic and diabetic rats, Nutritional Neuroscience DOI: 10.1080/1028415X.2018.1563664 (2018).

Aghanoori M, Smith DR, Shariati-Ievari S, Ajisebutu A, Nguyen A, Desmond F, Calcutt NA, Aliani M and Fernyhough P. Insulin-like growth factor-1 augments mitochondrial function through AMPK to drive axonal repair and protect from sensory neuropathy in type 1 diabetes. Molecular Metabolism. Accepted in Press (2018).

Zhou R, Grant J, Goldberg E, Ryland D, Aliani M. Investigation of low molecular weight peptides (<1KDa) in chicken meat and their contribution to meat flavor formation. J Sci Food Agr. 2018; DOI 10.1002/jsfa.9362.

Ryland D, Taylor C, Zahradka P, Bell RC and Aliani M. Acceptability of pulse fortified foods by two groups: participants in a clinical trial and participants in a consumer acceptability panel Foods. 2018; Accepted in Press.

Santiago A, Ryland D, Cui SM, Blewett H and Aliani M. Effect of milled flaxseed and storage conditions on sensory properties and selected bioactive compounds in banana and cinnamon muffins used in a clinical trial. J Sci Food Agr. 2018; https://doi.org/10.1002/jsfa.9253.

Ramdath DD, Wolever TM, Ryland D, Siow YL, Hawke A, Taylor C, Zahradka P and Aliani M, Effect of processing on postprandial glycemic response and consumer acceptability of lentil containing food items.  Foods 2018, 7, 76; doi:10.3390.

Ball HC, Shariati-Ievari S, Cooper LN and Aliani M, Comparative metabolomics of aging in a long-lived bat: Insights into the physiology of extreme longevity. PLoS One. 2018 May 1;13(5):e0196154. doi: https://doi.org/10.1371/journal.pone.0196154

Bell RC, Zahradka P, Aliani M, Liang YZ, McCargar LJ, Chan C, Ozga J, Proctor S, Wishart D and Taylor C, Dried beans lower cholesterol and glycated hemoglobin while peas lower blood pressure in adults with mild hypercholesterolemia. Faseb J 31 2017.

Goldberg, E and Aliani M (2017) Metabolomics and fetal alcohol spectrum disorder: A Mini-Review. Biochemistry and Cell Biology. DOI: 10.1139/bcb-2017-0080

Grant J, Ryland D, Isaak CK, Prashar S, Siow YL, Taylor CG, Aliani M (2017) Effect of addition of Saskatoon berry syrup and vitamin D3 fortification on the flavor profile, acceptability and antioxidant properties of rooibos tea Journal of Food Science 13 FEB 2017, DOI: 10.1111/1750-3841.13646

Book: Aliani, M. and Eskin, M. N. A., Bitterness: Perception, Chemistry and Food Processing. Wiley Blackwell, IFT Press: Oxford.
Click here for more information (.pdf)

Ahmed, N.; Beazabe, T.; Ijare, O.; Myers, R.; Aliani, M.; Alomran, R.; Aliani, M.; Nugent, Z.; Banerji, S.; Kim, J.; Qing, G.; Bshouty, Z., Metabolic Signatures of Lung Cancer in Sputum and Exhaled Breath Condensate Detected by 1H Magnetic Resonance Spectroscopy: A Feasibility Study. Magnetic Resonance Insights 2016, 9 29-35.

Hanson, G. M.; Zahradka, P.; Taylor, G. C.; Aliani, M., Identification of urinary metabolites with potential blood pressure lowering effects in lentil-fed spontaneously hypertensive rats. European Journal of Nutrition 2016, DOI 10.1007/s00394-016-1319-5.

Austria, J. A.; Aliani, M.; Malcolmson, L. J.; Dibrov, E.; Blackwood, D. P.; Maddaford, T. G.; Guzman, R.; Pierce, G. N., Daily choices of functional foods supplemented with milled flaxseed by a patient population over one year. Journal of Functional Foods 2016, 26, 772-780.

Erin Goldberg, Kun Wang, Jessica Goldberg and M. Aliani. 2016 Accepted In Press. " Factors affecting the orthonasal and retronasal perception of flavors: A review."  Journal of Critical Reviews in Food Science and Nutrition

Shariati-Ievari, S., T. Nicholson, D. Ryland, A. L. Edel, M. Suh, and M. Aliani. 2016 Accepted In Press. "Sensory and physico-chemical studies of thermally micronized chickpea (Cicer arietinum) and green lentil (Lens culinaris) flours as binders in low-fat beef burgers."  Journal of Food Science.

Onuh, John O., A. T. Girgih, I. Nwachukwu, S. Ievari-Shariati, P. Raj, T. Netticadan, E. R. Aluko, and M. Aliani. 2016, 22 (20-23). "A metabolomics approach for investigating urinary and plasma changes in spontaneously hypertensive rats (SHR) fed chicken skin protein hydrolysates diets."  Journal of Functional Foods.

Goldberg, E., D. Ryland, M. Aliani, and J. House. (2016) "Interactions between canola meal and flaxseed oil in the diets of white Lohmann hens on fatty acid profile and sensory characteristics table eggs."  Poultry Science. 0:1-8.

Onuh, John O., A. T. Girgih, I. Nwachukwu, S. Ievari-Shariati, P. Raj, T. Netticadan, E. R. Aluko, and M. Aliani. 2016 Accepted In Press. "A metabolomics approach for investigating urinary and plasma changes in spontaneously hypertensive rats (SHR) fed chicken skin protein hydrolysates diets." Journal of Functional Foods.

Grant, J., K. Whitehurst, C. G. Taylor, P. Zahradka, and M. Aliani. 2015. "Urinary metabolomics profile of genetically obese rats using liquid chromatography quadrupole time-of-flight mass spectrometry."  Jacobs Journal of Biomarkers 1(3):015.

Mughal W, et al. (2015). A conserved MADS-box phosphorylation motif regulates differentiation and mitochondrial function in skeletal, cardiac, and smooth muscle cells. Cell Death & Disease. doi:10.1038/cddis.2015.306.

Edel AL, Aliani M, Pierce NG (2015) Stability of Bioactives in Flaxseed and Flaxseed-Fortified Foods. Food Research International 77 (2015) 140–155.

Edel AL, Pierce GN, Aliani M (2015) Age-dependency in the metabolism of flaxseed lignans by healthy adults. Journal of Functional Foods. 17:948-957.

Mayengbam, S., House, J. D., & Aliani, M. (2015). A non-targeted metabolomic approach to identify potential plasma lipophilic biomarkers of inadequate vitamin B6 status, induced by low B6 intake, exposure to the anti-B6 factor 1-amino D-proline, or their interaction, in a rat model. European Journal of Nutrition. DOI 10.1007/s00394-015-0934-x.

Troy J Pereira, et al. (2015, Accepted In Press). Maternal obesity characterized by gestational diabetes increases susceptibility of rat offspring to hepatic steatosis via a disrupted liver metabolome. The Journal of Physiology. doi: 10.1113/JP270429

Edel, A. L., Patenaude, A. F., Richard, M. N., Dibrov, E., Austria, J. A., Aukema, H. M., Pierce. G. N., Aliani, M. (2015). The effect of flaxseed dose on circulating concentrations of alpha-linolenic acid and secoisolariciresinol diglucoside derived enterolignans in young, healthy adults. European Journal of Nutrition.

Edel, A. L., et al. (2015). Dietary flaxseed lowers circulating cholesterol independently and also increases the effects of cholesterol-lowering medications in patients with peripheral artery disease. The Journal of Nutrition, Doi: 10.3945/jn.114.204594.

Onuh, O. J., Girgih, A. T., Malomo, S. A., Aluko, E. R., & Aliani, M. (2015). Kinetics of in vitro renin and angiotensin converting enzyme inhibition by chicken skin protein hydrolysates and their blood pressure lowering effects in spontaneously hypertensive rats. Journal of Functional Foods, 14:133-43.

Mayengbam, S., Raposo, S., Aliani, M., & House, J. (2014). Oral exposure to the anti-pyridoxine compound 1-amino D-proline further perturbs homocysteine metabolism through the transsulphuration pathway in moderately vitamin B6-deficient rats. Journal of Nutritional Biochemistry, S0955-2863(14)00242-3.

Caligiuri, S. P. B., Edel, A. L., Aliani, M., & Pierce, G. N. (2014). Flaxseed for hypertension: implications for blood pressure regulation. Current Hypertension, 16(12), 499.

Clark, J., Rech, L., Nazia Chaity, N., Sihag, J., Taylor, C. G., & Aliani, M. (2014). Possible deleterious hormonal changes associated with low sodium diets: A Review. Nutrition Reviews, 73(1), 22-35.

Durunna, O. N., Block, H. C., Iwaasa, A. D., Scott, S. L., Robins, C., Khakbazan, M., . . . Lardner, H. A. (2014). Impact of calving season and finishing systems on steer post-weaning performance, carcass characteristics and steak qualities. Canadian Journal of Animal Science, 94(4), 583-593.

Mayengbam, S., Yang, H., Barthet, V., Aliani, M., & House, J. D. (2014). Identification, characterization and quantification of an anti-pyridoxine factor from flax seed using Ultra High Performance Liquid Chromatography-Mass Spectrometry. Journal of Agricultural and Food Chemistry, 62(2), 419-426.

Goldberg, E., Ryland, D., Gibson, R., Aliani, M., & House, J. (2013 ). Designer laying hen diets to improve egg fatty acid profile and maintain sensory quality. Food Science and Nutrition, 1, 324-335. doi: doi: 10.1002/fsn3.47

Holub, B., Mutch, D., Pierce, G. N., Rodriguez, D., Aliani, M., Innis, S. M., . . . Couture, P. (2014). Proceedings from the 2013 Canadian Nutrition Society Conference on Advances in Dietary Fats and Nutrition. Applied Physiology, Nutrition, and Metabolism, 39(7), 754-762.

Onuh, O. J., Girgih, A. T., Aluko, R. E., & Aliani, M. (2013a). In vitro antioxidant properties of chicken skin enzymatic protein hydrolysates and its membrane fractions. Food Chemistry, 150, 366–373.

Onuh, O. J., Girgih, A. T., Aluko, R. E., & Aliani, M. (2013b). Inhibitions of renin and angiotensin converting enzyme activities by enzymatic chicken skin protein hydrolysates. Food Research International, 53, 260-267.

Rodriguez-Leyva, D., Weighell, W., Edel, A. L., LaVallee, R., Dibrov, E., Pinneker, R., . . . Pierce, G. N. (2013). Potent antihypertensive action of dietary flaxseed in hypertensive patients. Hypertension, 62(6), 1081-1089.

Surendiran, G., ChunYan, G., Le, K., Zhaohui, Z., Askarian, F., Othman, R., . . . Moghadasian, H. M. (2013). Wild rice (Zizania palustris L.) prevents atherogenesis in LDL receptor knockout mice. Atherosclerosis, 230(2), 284-292.

Williamson, J., Ryland, D., Suh, M., & Aliani, M. (2014). The effect of chilled conditioning at 4ºC on selected water and lipid-soluble flavor precursors in Bison bison longissimus dorsi muscle and their impact on sensory characteristics. Meat Science, 96, 236-246.

Young, J. K., Giesbrecht, H. E., Eskin, M. N. A., Aliani, M., & Suh, M. (2014). Nutrition implications for Fetal Alcohol Spectrum Disorder. Advances in Nutrition, 5(6), 675-692.

Li, S., M, Aliani, and R.A. Holley. 2013. Sensory evaluation of dry-fermented sausage containing ground deodorized yellow mustard. J. Food Sci. 78:S1595-S1601.

Onuh OJ, Girgih AT, Aluko ER, Aliani M. 2013. Inhibitions of renin and angiotensin converting enzyme activities by enzymatic chicken skin protein hydrolysates. Food Research International 53:260-267.

Goldberg, E., Ryland, D., Gibson, R., Aliani, M., and House, J., 2013 Fatty acid profile and sensory characteristics of table eggs from laying hens fed designer diets to increase yolk docosahexaenoic acid (DHA) while decreasing omega-6 fatty acids: Food Science and Nutrition, 1:324-35.

Aliani, M., Udenigwe, C. C., Girgih, A. T., Pownall, T. L., Bugera, J. L., and Eskin, M. N. A., 2013, Aroma and taste perceptions with alzheimer and stroke: Critical Reviews in Food Science and Nutrition, v. 53, p. 760-769.

Michel Aliani , Chibuike C. Udenigwe , Abraham T. Girgih , Trisha L. Pownall , Jacqeline L. Bugera & Michael N. A. Eskin (2013): Zinc Deficiency and Taste Perception in the Elderly, Critical Reviews in Food Science and Nutrition, 53:3, 245-250

Aliani, M., Ryland, D., Williamson, J., & Rempel, N. (2013). The synergistic effects of ribose, carnosine and ascorbic acid on the sensory and physico-chemical characteristics of minced bison meat. Food Science & Nutrition, DOI: 10.1002/fsn3.25.

Aliani, M., Farmer, L. J., Kennedy, J. T., Moss, B. W., & Gordon, A. (2013). Post-slaughter changes in ATP metabolites, reducing and phosphorylated sugars in chicken meat. Meat Science, 94(55-62).

Edel, A. L., Aliani, M., & Pierce, G. N. (2013). Supported liquid extraction in the quantitation of plasma enterolignans with application to flaxseed consumption in healthy adults using isotope dilution GC/MS. Journal of Chromatography B, 912, 24-32

Sapirstein, H., Sidhu, S., & Aliani, M. (2012). Discrimination of Volatiles of Refined and Whole Wheat Bread Made from Red and White Wheat Bran Using an Electronic Nose. Journal of Food Science, 2012;77:S399-S406.

Goldberg EM, Gakhar N, Ryland D, Aliani M, Gibson RA and House JD. (2012) Fatty acid profile and sensory characteristics of table eggs from laying hens fed hempseed and hempseed oil. Journal of Food Science. In Press.

Aliani, M., Ryland, D., and Pierce, G.N. (2012) Effect of flax addition on the flavor profile and acceptability of bagels. Journal of Food Science, 71, S62-S70.

Rodriguez-Leyva, D., Zahradka, P., Ramjiawan, B., Guzman, R., Aliani, M. & Pierce, G. N. (2011) The effect of dietary flaxseed on improving symptoms of cardiovascular disease in patients with peripheral arterial disease: The FLAX-PAD Study. Contemporary Clinical Trials 2011; 32:724-730.

Aliani, M.;
Ryland, D.; Pierce, G., (2011) Effect of flax addition on the flavor profile of muffins and snack bars, Food Research International 44, 2489-2496.

Aliani, M. ; Udenigwe, C. ; Girgih, A.; Pownall, T. L,; Bugera, J. L.; Eskin, M. N. A. Aroma and taste perceptions with Alzheimer and. Critical Reviews in Food Science and Nutrition. 2010. Accepted.

Aliani, M., Kennedy, J.T., McRoberts, C.W., & Farmer, L.J. 2008. Formation of flavor precursors by the AMP pathway in chicken meat. In: Blank, I., Wust, M., & Yeretzian, C. (Eds). Expression of Multidisciplinary Flavour Science. Proceedings of The XIIth Weurman Flavor Research Symposium. Interlaken, Switzerland: Institut fur Chemie und Biologische Chemie, pp. 288-292.

Khattab, R.; Eskin, N. A. M.; Aliani, M.; Thiyam, U.; Determination of Sinapic Acid Derivatives in Canola Extracts using High-Performance Liquid Chromatography. Journal of the American Oil Chemists Society. 2010. 87:147–155.

Eskin, N. A. M, Aliani, M. Enzymatic degradation of food. In 'Enzymatic Deterioration of Plant Foods' edited by Skibstead, 2010. 519-538

Aliani, M.; Farmer, L. J. A post-column derivatization method for determination of reducing and phosphorylated sugars in chicken by high performance liquid chromatography. Journal of Agricultural and Food Chemistry 2002, 50, 2760-2766.

Aliani, M.; Farmer, L. J. Precursors of chicken flavor. I. Determination of some flavor precursors in chicken muscle. Journal of Agricultural and Food Chemistry 2005, 53, 6067-6072.

Aliani, M.; Farmer, L. J. Precursors of chicken flavor. II. Identification of key flavor precursors using sensory methods. Journal of Agricultural and Food Chemistry 2005, 53, 6455-6462.

Aliani, M.; Farmer, L. J. Studies on the formation of chicken flavor. Feedinfo News Service Scientific Reviews February 2006, Available form URL: http://www.feedinfo.com/.

Website: The formation of chicken flavor, an introduction by Michel Aliani http://chicken-flavor.tripod.com/.