PLNT 4330 INTERMEDIATE GENETICS

FALL 2010

INSTRUCTOR: Dr. M. Tahir
OFFICE: 305 Agriculture Building (Department of Plant Science)
E-mail: tahir@cc.umanitoba.ca Telephone: 474-6076
OFFICE HOURS: By appointment

Lectures: 11:30 Mon, Wed, Fri 134 Agriculture Building
Tutorials: 2:30 Fri 134 Agriculture Building

TA for Tutorials: Roger Watts
306 Agriculture Building
Email: umwatts4@cc.umanitoba.ca
Phone: 226-8400


Objectives:
1. To introduce the student to additional genetic information and concepts beyond an introductory course.
2. To familiarize the student with plant genetics terminology and concepts.
3. To prepare the student for further undergraduate and graduate courses in genetics.

SUBJECT MATTER OF COURSE:
The course covers a broad spectrum of topics in genetics including:
Altered segregation large changes in genetic material cytoplasmic genetics
Statistics population genetics mutations
Linkage quantitative genetics genetic engineering
Plant examples are used whenever possible.

REQUIRED TEXTBOOK:
Stansfield, W. D. (2010) GENETICS 5th Edition. Schaum’s Outline Series. McGraw-Hill Inc. Toronto
AVAILABLE AT THE UNIVERSITY BOOKSTORE

GRADING SYSTEM:

SCHEDULE:


Tutorial Exam I,
15%, Friday, October 22, 2010

Midterm Lecture Exam, 25%, Friday, October 29, 2010

Tutorial Exam II, 15%, Friday, December 03, 2010

Final Lecture Exam, 45%, Scheduled by Student Records in the December examination period.

Grades from the Class Mid-Term will be available prior to the voluntary withdrawal deadline of November 17, 2010.

Academic Regulations and Policy:
NOTE: Students are reminded that academic dishonesty including plagiarism, cheating and examination impersonation is subject to severe academic penalties as outlined in the 2010 – 2011 University of Manitoba Undergraduate Calendar, Section 8.

8.1 Plagiarism and Cheating
Plagiarism or any other form of cheating in examinations, term tests or academic work is subject to serious academic penalty (e.g. suspension or expulsion from the faculty or university). Cheating in examinations or tests may take the form of copying from another student or bringing unauthorized materials into the exam room (e.g., crib notes, pagers or cell phones). Exam cheating can also include exam impersonation. (Please see Section 5.2.9 on Exam Personation). A student found guilty of contributing to cheating in examinations or term assignments is also subject to serious academic penalty.
To plagiarize is to take ideas or words of another person and pass them off as one's own. In short, it is stealing something intangible rather than an object. Plagiarism applies to any written work, in traditional or electronic format, as well as orally or verbally presented work. Obviously it is not necessary to state the source of well known or easily verifiable facts, but students are expected to appropriately acknowledge the sources of ideas and expressions they use in their written work, whether quoted directly or paraphrased. This applies to diagrams, statistical tables and the like, as well as to written material, and materials or information from Internet sources.
To provide adequate and correct documentation is not only an indication of academic honesty but is also a courtesy which enables the reader to consult these sources with ease. Failure to provide appropriate citations constitutes plagiarism. It will also be considered plagiarism and/or cheating if a student submits a term paper written in whole or in part by someone other than him/herself, or copies the answer or answers of another student in any test, examination, or take-home assignment.
Working with other students on assignments, laboratory work, take-home tests, or on-line tests, when this is not permitted by the instructor, can constitute Inappropriate Collaboration and may be subject to penalty under the Student Discipline By-Law.
An assignment which is prepared and submitted for one course should not be used for a different course. This is called "duplicate submission" and represents a form of cheating because course requirements are expected to be fulfilled through original work for each course.
When in doubt about any practice, ask your professor or instructor.

LECTURE OUTLINE

Topics

I. Review of Mendelian Principles

1. Nucleic acids, mitosis, meiosis and gametogenesis
2. Segregation, assortment, dominance relationships, multiple allelic series


II. Altered Segregation

3. Altered segregation I
4. Altered segregation II
5. Gene interaction - epistasis


III. Statistics in Genetics

6. Probability, chi squared tests
7. Distributions and minimum family size


IV. Gene linkage, Recombination and Mapping

8. Detection of linkage
9. Gene mapping in diploids I
10. Gene mapping in diploids II
11. Linkage and mapping in fungi
12. Linkage and mapping in bacteria

V. Large Changes in Genetic Material

13. Variation in chromosome numbers
14. Segregation and linkage in polyploids I


15. Segregation and linkage in polyploids II
16. Changes in chromosome structure

VI. Genes in Populations

17. Gene frequencies and equilibrium
18. Factors operating to direct change I
19. Factors operating to direct change II
20. Factors operating to direct change III
21. Factors operating to direct change IV
22. Inbreeding

 


VII. Quantitative Genetics

23. Is part of continuous variation heritable?
24. Analysis of quantitative characters using means
25. Analysis of quantitative characters using variances
26. Genetic and Molecular Markers
27. Analysis of quantitative trait loci using molecular markers
28. Applications in Plant and Animal Improvement

VIII. Cytoplasmic Genetics

29. Maternal effects and cytoplasmic inheritance
30. Mitochondria and plastid gene transmission and recombination
31. Cytoplasmic male sterility systems and plant breeding


IX. Mutation, Genetic Engineering

32. Gene mutation
33. Induced genetic changes
34. Genetic engineering and crop improvement I
35. Genetic engineering and crop improvement II


Review / Final Lecture Exam Preparation